archive-edu.com » EDU » C » CASE.EDU

Total: 920

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".
  • Burning mouth syndrome is often difficult to diagnose | think:blog
    or dry feeling in the mouth Symptoms that disappear when eating Burning sensations may migrate across several oral areas Even if oral pain is present without these symptoms Pinto recommended consulting a dentist for a thorough exam of the teeth gums mouth and throat Between two and five percent of the U S population acquires BMS he said but the syndrome especially strikes women between age 50 and 70 and from three years before to 12 years after menopause Early research in BMS explored the association with local oral changes that could be corrected by dentists and the observed comorbidity with psychogenic disorders Changes in neurologic sensory function in patients with BMS and reported cases of secondary BMS to anemia diabetes vitamin deficiency and thyroid disorders triggered further exploration into peripheral neural changes and central nervous system brain mechanisms that could contribute to the causes of this condition Although the exact cause of BMS is unknown the suspected origin is deterioration of the nerves beneath the oral lining The deterioration isn t visible which explains why the mouth appears normal when examined and can delay diagnosis Pinto explained Still unproven is the role hormones may play in BMS given the link to menopause The pain from BMS often results in quality of life issues from poor nutrition to the sufferer withdrawing from social situations In some cases the pain is so severe it has driven people to commit suicide Pinto said Patients can receive relief with special mouthwashes analgesics and other topical and systemic treatments Pinto recently joined a research team to learn what postgraduate programs in dental schools are teaching about BMS The researchers report in the October issue of the Journal of the American Dental Association that BMS is being taught but more needs to be done Pinto

    Original URL path: http://blog.case.edu/think/2013/10/23/burning_mouth_syndrome_is_often_difficult_to_diagnose (2015-11-11)
    Open archived version from archive


  • CWRU’s Mandel School faculty to aid Romania’s outdated adoption process | think:blog
    process was in place But in the 1990s and later a new adoption system began to emerge to protect the children halt unscrupulous intercountry adoption practices and promote domestic adoptions While Romanian universities have been able to reestablish their social work programs they still provide limited information on clinical and practice issues in adoption This collaboration will help them strengthen their adoption curriculum and ultimately help lead to an increase in domestic adoptions Groza and Zoe Breen Wood assistant professor at the Mandel School will direct the collaboration that includes Karen Rosenberg a clinical supervisor of adoption programs in Cleveland and Groza s coauthor on the book Clinical Practice and Issues in Adoption The group also includes Romanian adoption experts Ana Muntean as onsite project director Cosmin Goian director of WUT s social work program and Roxana Ungureanu onsite project coordinator and a research assistant at the Research Center Based on Child Parent Interactions Wood said the program is modeled after continuing education programs offered to adoption workers in Cuyahoga County public and private social service agencies and is meant to strengthen the adoption competence of practitioners who work with adoptees and their families Starting in November Romanian child welfare workers with master s degrees in social work or psychology will be eligible for 10 three hour training sessions taught by Mandel School faculty and alumni by videoconference Each session focuses on a different aspect of the adoption process Muntean will provide interpretation when needed Attendees also will receive electronic copies of Groza s and Rosenberg s book translated to Romanian Romanian adoption workers will be taught the long term and short term effects of institutionalization on children to transition children from foster care to adoptive families to conduct interventions social and mental health services for adoptees at different ages and developmental stages and to match child qualities with parent expectations A sub group of these adoption workers will be chosen for six months of post training and special supervision earning a post master s certificate in adoption counseling Groza who traces his roots to Romania has worked for 22 years to improve conditions for Romanian children who were orphaned or abandoned Romania has realized that institutions are no longer a place to call home he said There is still work to be done but Romania is now a very different place than most people saw in the early 1990s Those institutions once housed children who were relinquished by parents who lacked financial means to support them At the time the Romanian government imposed a five children policy that required and rewarded all families to have at least that many children He said the government misled parents to think their children were better off under state care International and domestic pressure eventually forced Romania to reform and transition institutional care to foster families but the next step is to increase the number of permanent adoptive homes Groza said But adoption workers and families seeking to adopt need to understand the

    Original URL path: http://blog.case.edu/think/2013/10/23/cwruas_mandel_school_faculty_to_aid_romaniaas_outdated_adoption_process (2015-11-11)
    Open archived version from archive

  • Justices to Consider EPA Air Pollution Regulation | think:blog
    motor vehicles triggered permitting requirements under the Clean Air Act for stationary sources that emit greenhouse gases According to Adler the question now before the Court is whether the EPA correctly determined that its own decision to regulate greenhouse gas GHG emissions from motor vehicles automatically gave the agency authority to regulate emissions from stationary sources as well such as power plants and oil refineries The EPA regulations are among measures President Obama sought to reduce climate change A federal appeals court in Washington upheld the rules issued by the EPA in 2012 under the Clean Air Act rejecting challenges to the first ever federal regulations governing GHG emissions By agreeing to hear the legal claims raised by states and business groups the Court will have the opportunity to clarify the reach of its 2007 decision in Massachusetts v EPA in which the Court held GHG emissions could be regulated as pollutants under the Clean Air Act The grant is welcome despite the limitations Adler said Many of the questions for which industry sought review such as whether the EPA properly considered the relevant scientific research or set permissible standards for vehicular emissions under Section 202 of the Clean Air Act were not cert worthy Adler is the inaugural Johan Verheij Memorial Professor of Law and director of the Center for Business Law Regulation at the Case Western Reserve University School of Law where he teaches courses in environmental administrative and constitutional law Adler has written or edited four books on environmental policy and has had his scholarship cited by the Supreme Court He participated in an amicus brief of legal academics urging the Court to grant certiorari in this case Reporters and editors note More information about Jonathan H Adler is available at his Case Western Reserve University School

    Original URL path: http://blog.case.edu/think/2013/10/22/justices_to_consider_epa_air_pollution_regulation (2015-11-11)
    Open archived version from archive

  • CWRU researchers make nanodiamonds in ambient conditions | think:blog
    pressure and high temperature a process known as chemical vapor deposition that is now used to make coatings on computer disks and razor blades Sankaran s specialty meanwhile is making nanoparticles using cool microplasmas It usually requires high pressures and high temperatures to convert graphite to diamond or a combination of hydrogen gas and a heated substrate to grow diamond rather than graphite But at the nanoscale surface energy makes diamond more stable than graphite Sankaran explained We thought if we could nucleate carbon clusters in the gas phase that were less than 5 nanometers they would be diamond instead of graphite even at normal pressure and temperature After several ups and downs with the effort the process came together when Kumar joined Sankaran s lab The engineers produced diamond much like they d produce carbon soot They first create a plasma which is a state of matter similar to a gas but a portion is becoming charged or ionized A spark is an example of a plasma but it s hot and uncontrollable To get to cooler and safer temperatures they ionized argon gas as it was pumped out of a tube a hair width in diameter creating a microplasma They pumped ethanol the source of carbon through the microplasma where similar to burning a fuel carbon breaks free from other molecules in the gas and yields particles of 2 to 3 nanometers small enough that they turn into diamond In less than a microsecond they add hydrogen The element removes carbon that hasn t turned to diamond while simultaneously stabilizing the diamond particle surface The diamond formed is not the large perfect crystals used to make jewelry but is a powder of diamond particles Sankaran and Kumar are now consistently making high quality diamonds averaging 2 nanometers in diameter The researchers spent about a year of testing to verify they were producing diamonds and that the process could be replicated Kumar said The team did different tests themselves and brought in Yap s lab to analyze the nanoparticles by Raman spectroscopy Currently nanodiamonds are made by detonating an explosive in a reactor vessel to provide heat and pressure The diamond particles must then be removed and purified from contaminating elements massed around them The process is quick and cheap but the nanodiamonds aggregate and are of varying size and purity The new research offers promising implications Nanodiamonds for instance are being tested to carry drugs to tumors Because diamond is not recognized as an invader by the immune system it does not evoke resistance the main reason why chemotherapy fails Sankaran said his nanodiamonds may offer an alternative to diamonds made by detonation methods because they are purer and smaller The group s process produces three kinds of diamonds about half are cubic the same structure as gem diamonds a small percentage are a form suspected of having hydrogen trapped inside and about half are lonsdaleite a hexagonal form found in interstellar dust but rarely found on Earth

    Original URL path: http://blog.case.edu/think/2013/10/21/cwru_researchers_make_nanodiamonds_in_ambient_conditions (2015-11-11)
    Open archived version from archive

  • CWRU researchers test biofeedback device in lowering grandmothers’ stress | think:blog
    negative emotions and depressive thoughts and help grandmothers cope with the added responsibilities While the study was small it showed promise in that self reported stress and negative thoughts were reduced during and after using the device The researchers report their findings in the article Heart Rate Variability Biofeedback in Grandmothers Raising Grandchildren Effects on Stress Emotions and Cognition in the special issue of Biofeedback from the Association for Applied Psychophysiology Biofeedback The researchers wanted the grandmothers to become more aware of how their bodies react to stress to help reduce the tension and associated heath risks such as high blood pressure heart disease and depression The grandmothers were recruited with flyers in health centers churches and businesses The average age of the women was 58 ranging from 42 to 68 and average income was 50 000 The study group was evenly divided racially by African Americans and Caucasians and by educational level of those who have a college degree and those who do not The grandmothers used the device at home for four weeks They were taught to insert their left index finger into the sensor clip on the devise that detects their pulse rate and while doing so to inhale and exhale slowly while observing waves on the device s screen Thus over time they learn to coordinate their breathing with their heart rate The women provided information about their perceived stress negative emotions and depressive thoughts by questionnaire Researchers then collected data from the device in four face to face interviews spaced six weeks apart The first significant improvement came two weeks after using the device and also at eight and 14 weeks The researchers suggest that the noticeable reduction in stress warrants a larger study print e mail feeds connect Get in touch with Case Western

    Original URL path: http://blog.case.edu/think/2013/10/07/cwru_researchers_test_biofeedback_device_in_lowering_grandmothersa_stress (2015-11-11)
    Open archived version from archive

  • Making a better, cheaper green-energy magnet | think:blog
    the carbon concentration in stainless steel way beyond the usual equilibrium solubility limit We ve had to go to the old literature to learn what materials the industry was working on before rare earth metals came along and why everybody has failed at producing a powder made of the material with the highest known magnetic remanence Matthiesen said Remanence is the strength of the magnetic field a material produces after the material is magnetized The higher the remanence the smaller the mass of material needed to convert mechanical and electrical energy in a generator or vice versa in a motor In seeking a solution the engineers returned to the science used to make ancient samurai swords which had a hard sharp but brittle cutting edge on a flexible blade Centuries after manufacturing had begun scientists understood that the flexible blade was cooled slowly but the edge was cooled rapidly which resulted in a steel packed with carbon atoms differently than the slow cooled steel After World War II Cambridge University scientist Kenneth H Jack used X rays to understand the structural changes He found that the distribution of iron and carbon atoms in an alloy and the distribution of iron and nitrogen atoms in a second alloy were nearly identical when cooled the same way Rapidly cooling the iron nitrogen alloy produced a form of Fe16N2 called alpha prime which is a disordered form meaning it s nitrogen atoms are randomly arranged When heated again the compound turns into another form of Fe16N2 called alpha double prime This form contains the same concentration of nitrogen atoms but they re arranged in an order that yields a higher concentration of unpaired electrons Unpaired electrons are essential to magnetic remanence Jack didn t mention magnetic properties in his reports but Japanese researchers found when they produced a thin film of pure alpha double prime to make a computer hard drive that the compound has the highest remanence of any material known So far however no one has been able to make powder that could be used to manufacture large industrial magnets Scientists have been unable to dissolve enough nitrogen into iron to fully transform the solid solution into A partial transformation results in a correspondingly weaker magnet Matthiesen believes fellow materials science and engineering professors Frank Ernst Arthur Heuer and Gary Michal may have found the keys During the last decade they developed a way to dissolve carbon or nitrogen in stainless steel that exceeds the natural equilibrium solubility limit up to 100 000 fold We believe that combining all these bits of information will enable us to make bulk powders of with properties to make a practical magnet and replace neodymium iron boron magnets Matthiesen said With the new round of funding the group has added Ames National Laboratory in Ames Iowa to the effort The Ames Lab is providing a starting powder of specially engineered spherical alloy particles The engineers will design and build a fluidized bed reactor at Case

    Original URL path: http://blog.case.edu/think/2013/10/07/making_a_better_cheaper_greenenergy_magnet (2015-11-11)
    Open archived version from archive

  • Feds fund concept for cheaper, better titanium made in U.S. | think:blog
    applications in aerospace transportation and defense However the current process used to refine titanium from ore is extremely energy intensive making titanium expensive thus limiting its widespread use Our project if successful will lower the cost of titanium by up to 60 percent said Rohan Akolkar associate professor of chemical engineering and the principal investigator on the project Akolkar s team which also includes Uziel Landau professor and chair of chemical engineering and Mark De Guire associate professor of materials science and engineering will work towards demonstrating feasibility of their idea in the next year The CWRU team proposes to use an electrolytic process called electrowinning to directly extract titanium from molten titanium salts A specialized electrochemical reactor will be designed and built at CWRU to facilitate a stable electrowinning process to produce the metal Much of the cost associated with extracting titanium via conventional non electrolytic routes lies in processing the sacrificial reducing agent which is typically magnesium In our direct electrolytic process magnesium is not required Akolkar said This reduces cost reduces energy consumption and simplifies the overall process The electrolytically extracted titanium is expected to contain fewer impurities and therefore have superior mechanical properties as extracted The team s process has the potential of considerably expanding the domestic titanium production industry which is important to U S security It can boost manufacturing and lower the reliance on titanium imports which come mostly from Russia print e mail feeds connect Get in touch with Case Western Reserve University s media relations team Contact information photos news releases and more are available on our site Posted by Kevin Mayhood October 3 2013 11 57 AM News Topics Official Release advertising archives letters to the editor story tips subscribe search more to think about What makes you think Share photos

    Original URL path: http://blog.case.edu/think/2013/10/03/feds_fund_concept_for_cheaper_better_titanium_made_in_us (2015-11-11)
    Open archived version from archive

  • CWRU researchers probe brain implant failure and countermeasure | think:blog
    Western Reserve School of Medicine and a neurologist at the Louis Stokes Cleveland Veterans Administration Medical Center They will test microelectrodes commonly associated with brain computer interfacing applications Brain cells are damaged when any electrode is implanted which causes pro inflammatory molecules to accumulate around the electrode surface in turn causing the adjacent neurons to degenerate and compromising of the blood brain barrier Damaged cells and infiltrating blood components exacerbate the immune response and cause more neurons to die The electrodes can only record from healthy neurons close to the electrodes When the closest neurons die the devices fail to record high quality signals required to control devices Capadona explained The group is targeting a participant in the innate immune response a gene called cluster of differentiation 14 referred to as CD14 In work done while seeking this grant the group found CD14 coordinates immune cell recognition and binding of damaged cells and blood serum proteins part of the inflammatory response they believe eventually interferes with implants In testing the researchers gave models of mutant and healthy mice a CD14 antagonist that appears to inhibit the gene The result neuron loss around implanted electrodes was prevented They also found that when CD14 pathways were over stimulated the quality of neural recordings suffered The group will soon begin testing whether a drug can improve outcomes We have identified a drug that s been approved for another clinical use but which we believe patients can take and enable brain computer interfaces to work longer Capadona said The team will test whether their approach works like an anti rejection drug used by transplant patients affecting a specific pathway involving CD14 in a way that prevents the inflammatory immune response from killing the cells that the implant is trying to communicate with Additionally the

    Original URL path: http://blog.case.edu/think/2013/10/02/cwru_researchers_probe_brain_implant_failure_and_countermeasure (2015-11-11)
    Open archived version from archive



  •