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  • Home | Columbia University Department of Systems Biology
    in ways that modulate nearby gene expression They are also associated with a range of medical conditions Announcement Department of Systems Biology Opens New Biotechnology Development Hub The new space will promote the design of new experimental methods for studying biological systems and enable an expansion of the Columbia Genome Center s next generation sequencing capabilities Awards and Grants Andrea Califano Named NCI Outstanding Investigator The seven year grant will support the development of systematic approaches for identifying the molecular factors that lead to cancer progression and to the emergence of drug resistance at the single cell level Education Columbia Launches Undergraduate Synthetic Biology Team For this year s International Genetically Engineered Machine Foundation iGEM competition the team used synthetic biology methods to engineer edible probiotic bacteria that could regulate hunger and digestion Announcement Faculty Members Join Department of Systems Biology and C2B2 Kam Leong Biomedical Engineering has joined the Department as an interdisciplinary faculty member while Yaniv Erlich Computer Science and Guy Sella Biological Sciences bring new expertise to C2B2 Education Graduate Course Focuses on Foundations of Deep Sequencing The new team taught course provides an understanding of both the experimental principles of next generation sequencing technologies and key statistical methods for analyzing the data they produce Upcoming Events Department of Systems Biology Announces 2015 2016 Seminar Series This year s visiting speakers series will include Anshul Kundaje Nevan Krogan Sarah Tishkoff Jef Boeke and others Click on the link above for the complete schedule and mark your calendars Research News Promising New Targets for Treating HER2 Positive Breast Cancer Systems biology approaches have identified a signaling pathway responsible for a subtype of aggressive breast cancer as well as FDA approved drugs capable of targeting it A clinical trial is now underway to test the findings Awards and Grants Saeed Tavazoie Wins Transformative Research Award With the support of the NIH s High Risk High Reward Research program Tavazoie will develop a new technology combining experimental and computational methods to map all pairwise molecular interactions in the cell In the Press Kyle Allison Featured in NIH Director s Blog A post authored by NIH Director Francis Collins highlights Dr Allison s ongoing efforts to isolate and study persistent bacteria which in the clinic can often instigate dangerous chronic infections that are difficult to eliminate Education Putting Blended Learning to the Test Electronic media offer valuable tools for learning but what is the best way to integrate such technologies within the traditional university setting Brent and Melissa Stockwell recently conducted an innovative formal trial to find out Awards and Grants Oliver Hobert Named Javits Neuroscience Investigator This prestigious grant supports investigators who have demonstrated exceptional achievement throughout their careers It will enable the Hobert Lab to investigate sex based differences in the regulation of neuronal identity Events and Seminars More Events January 20 2016 3 00pm Nevan Krogan University of California San Francisco More information February 24 2016 3 00pm Michael Katze University of Washington More information March 2 2016

    Original URL path: http://systemsbiology.columbia.edu/ (2016-01-01)
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  • About the Department | Columbia University Department of Systems Biology
    a faculty of more than two dozen members and onsite research infrastructure for high performance computing next generation sequencing and high throughput screening we conduct research to understand the behavior of complex biological networks and how small changes in those networks produce the diversity of life around us We also provide PhD education and postdoctoral training to increase understanding of systems biology and promote its use in biological research Our research begins from the principle that physiologic and pathologic traits emerge from interactions within complex systems of genes proteins cells epigenetic influences and other factors CISB researchers use recent advances in technology both to develop models of these systems and to validate them in the laboratory We also develop software for the analysis of biological data and make it available for use by other researchers around the world Doing this work requires investigators with a wide range of interests Our program includes specialists in molecular biology genetics computational biology and bioinformatics mathematics chemistry and chemical biology physics computer science and other fields CISB supports basic science research in computational biophysics and structural biology as well as the modeling of regulatory signaling and metabolic networks pattern discovery and recognition machine learning and functional genomics We also conduct research in disease related areas such as cancer infectious diseases metabolic disorders and neurodegenerative disease as well as stem cell and regenerative medicine This is a sample image caption Since its founding in 2010 the Columbia Initiative in Systems Biology has coordinated the activities of the Center for Computational Biology and Bioinformatics C2B2 and the Columbia Genome Center We are also the home of seven centers of excellence including the Center for Multiscale Analysis of Genomic and Cellular Networks MAGNet one of eight National Centers for Biomedical Computing and one of 12 interdisciplinary Centers for Cancer Systems Biology By uniting Columbia s computational expertise with capabilities in high throughput experimentation and novel chemical synthesis CISB has developed an integrated model for twenty first century biological research Related News March 18 2013 Harris Wang Joins Columbia Initiative in Systems Biology Harris Wang has joined Columbia University Medical Center as an Assistant Professor in the Columbia Initiative in Systems Biology and the Department of Pathology and Cell Biology His research focuses on understanding the evolution of the ecosystems that develop within heterogeneous microbial communities Using approaches from genome engineering DNA synthesis and next generation sequencing he studies how genomes in microbial populations form maintain themselves and change over time both within and across microbial communities His goal is to use synthetic biology approaches to engineer ecologies of microbial populations such as those found in the gut and elsewhere in the human body in ways that could improve human health Read More Share Research Columbia Genome Center Center for Computational Biology Bioinformatics C2B2 Center for Multiscale Analysis of Genomic Cellular Networks MAGNet Library of Integrated Network Based Cellular Signatures LINCS Cancer Target Discovery Development Center CTD2 Center for Topology of Cancer Evolution and Heterogeneity International Serious Adverse

    Original URL path: http://systemsbiology.columbia.edu/about-the-department (2016-01-01)
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  • Department Overview | Columbia University Department of Systems Biology
    of life around us We also provide graduate education and postdoctoral training to increase understanding of systems biology and promote its use in biological research Download a pdf of our 2015 brochure hi resolution 9 MB low resolution 1 MB Our research begins from the principle that physiologic and pathologic traits emerge from interactions within complex systems of genes proteins cells epigenetic influences and other factors Our researchers use recent advances in technology both to develop models of these systems and to validate the accuracy of these models in the laboratory We also develop software for the analysis of biological data and make it available for use by other researchers around the world through a platform called geWorkbench Doing this work requires investigators with a wide range of interests Our program includes specialists in molecular biology genetics computational biology and bioinformatics structural biology mathematics chemistry and chemical biology physics computer science and other fields The Department of Systems Biology supports basic science research in computational biophysics and structural biology as well as the modeling of regulatory signaling and metabolic networks pattern discovery and recognition machine learning and functional genomics We also conduct research in disease related areas such as cancer infectious diseases metabolic disorders and neurodegenerative disease as well as stem cell and regenerative medicine The Department of Systems Biology coordinates the activities of the Center for Computational Biology and Bioinformatics and the Columbia Genome Center We are also the home of six centers of excellence including the Center for Multiscale Analysis of Genomic and Cellular Networks MAGNet one of eight National Centers for Biomedical Computing and one of 12 interdisciplinary Centers for Cancer Systems Biology By uniting Columbia s computational expertise with capabilities in high throughput experimentation and novel chemical synthesis the Department of Systems Biology has developed an

    Original URL path: http://systemsbiology.columbia.edu/department-overview (2016-01-01)
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  • News | Columbia University Department of Systems Biology
    Saville The Columbia University Department of Systems Biology has opened a new experimental research hub focused on biotechnology development Occupying one and a half floors in the Mary Woodard Lasker Biomedical Research Building at Columbia University Medical Center the facility will promote the design and implementation of new experimental methods for the study and engineering of biological systems It will also enable a substantial expansion of Columbia s next generation genome sequencing capabilities The first occupants of the new facility are the laboratories of Department of Systems Biology Assistant Professors Sagi Shapira Peter Sims and Harris Wang along with the Genome Sequencing and Analysis Center of the JP Sulzberger Columbia Genome Center The community is slated to grow as currently unoccupied space will soon accommodate additional Columbia University faculty labs that are also developing new biotechnologies Read More Share November 6 2015 Andrea Califano Named NCI Outstanding Investigator Andrea Califano the Clyde and Helen Wu Professor of Chemical Systems Biology and Chair of the Columbia University Department of Systems Biology has been named a recipient of a National Cancer Institute Outstanding Investigator Award The seven year grant will support the development of systematic approaches for identifying the molecular factors that lead to cancer progression and to the emergence of drug resistance at the single cell level Read More Share November 3 2015 Columbia Launches Undergraduate Synthetic Biology Team The Columbia University 2015 iGEM Team l r Hudson Lee Suppawat Kongthong Jacky Cheung Kenya Velez Samuel Magaziner and faculty moderator Harris Wang A team of undergraduate students based at Columbia University for the first time participated in this year s International Genetically Engineered Machine Foundation iGEM competition Supervised by Department of Systems Biology Assistant Professor Harris Wang the team spent this past summer developing a project that used synthetic biology methods to engineer an edible probiotic consortium of bacteria that could regulate hunger and digestion In September they presented their results at the iGEM Giant Jamboree in Boston MA where they received a silver medal for their efforts For more informtion about their project see the Columbia iGEM Team website I think it s fantastic that this ambitious group of undergraduates worked so hard to represent Columbia University on this international stage says Dr Wang Columbia has one of the great undergraduate colleges and now that we have a critical mass of interested students and faculty laboratories with expertise in synthetic biology we think iGEM offers a valuable opportunity to compete with and learn from teams at other leading institutions Read More Share October 30 2015 Faculty Members Join Department of Systems Biology and C2B2 The Department of Systems Biology and Center for Computational Biology and Bioinformatics are pleased to announce that three Columbia University faculty members have recently joined our community Kam Leong the Samuel Y Sheng Professor of Biomedical Engineering at Columbia University is now an interdisciplinary faculty member in the Department of Systems Biology In addition Yaniv Erlich and Guy Sella are now members of the Center for

    Original URL path: http://systemsbiology.columbia.edu/news (2016-01-01)
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  • Events | Columbia University Department of Systems Biology
    Center Genome Sequencing and Analysis High Throughput Screening Medium Throughput Screening People Software Overview Software List Careers Contact Us Search News News Publications Events People Site Search Search Systems Biology Home Columbia University Department of Systems Biology Columbia University Medical Center Home About Events About Overview News Events Careers Current Job Openings Contact Us January 20 2016 3 00pm Nevan Krogan University of California San Francisco More information February 24 2016 3 00pm Michael Katze University of Washington More information March 2 2016 3 00pm Gustavo Stolovitzky IBM Thomas J Watson Research Center More information March 23 2016 3 00pm Sumit Chanda Burnham Institute for Medical Research More information April 6 2016 3 00pm Sarah Tishkoff University of Pennsylvania More information April 27 2016 3 00pm Paul Spellman Oregon Health Science University More information May 11 2016 3 00pm Greg Hannon Cold Spring Harbor Laboratory More information May 25 2016 3 00pm Jef Boeke NYU Langone Medical Center More information 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2006 2005 2004 Research Columbia Genome Center Center for Computational Biology Bioinformatics C2B2 Center for Multiscale Analysis of Genomic Cellular Networks MAGNet Library of Integrated Network Based Cellular Signatures LINCS Cancer Target Discovery Development Center CTD2 Center for Topology of Cancer Evolution and Heterogeneity International Serious Adverse Event Consortium iSAEC Infrastructure Genome Sequencing and Analysis High Throughput Screening Medium Throughput Screening Information Technology DSBIT Education Training Graduate Education Postdoctoral Training About the Department News Events Contact Careers People Software Columbia University Medical Center Columbia University Columbia University Medical Center 2015 Columbia University Medical Center Columbia University Department of Systems Biology Irving Cancer Research Center 1130 St Nicholas Avenue New York NY 10032 212 851 5208 Overview News Events Col 2 Careers Current Job Openings Contact Us About Our Research Accomplishments

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  • Careers | Columbia University Department of Systems Biology
    the links below to find currently available opportunities You can also visit our page of Current Job Openings Research and Administrative Staff More information The Columbia University Medical Center human resources office maintains a current list of open positions for faculty laboratory research staff and administrative staff Postdoctoral Training More information The Columbia University Department of Systems Biology offers postdoctoral training opportunities for early career scientists interested in pursuing research in systems and computational biology Graduate Education More information Through courses laboratory rotations and doctoral research graduate students at Columbia learn to move smoothly between the worlds of experimentation and computation and develop the skills necessary to make significant contributions at the cutting edge of biomedical research Opportunities for Undergraduates If you are an undergraduate student with a strong scientific background and an interest in pursuing research in systems and computational biology the Department of Systems Biology offers opportunities to gain valuable experience ICBP Summer Internship Program More information As a member of the National Cancer Institute s Integrated Cancer Biology Program Columbia University offers opportunities for college sophomores juniors and seniors to spend a summer working in laboratories doing cancer research Summer Program for Under Represented Students SPURS More information SPURS awards fellowships to undergraduates from diverse and economically disadvantaged backgrounds giving the opportunity to spend a summer working in a laboratory at Columbia University Students gain knowledge about biology and biomedical research as well as valuable experience designing experiments making presentations and posters and participating in journal clubs and seminars Research Columbia Genome Center Center for Computational Biology Bioinformatics C2B2 Center for Multiscale Analysis of Genomic Cellular Networks MAGNet Library of Integrated Network Based Cellular Signatures LINCS Cancer Target Discovery Development Center CTD2 Center for Topology of Cancer Evolution and Heterogeneity International Serious Adverse Event Consortium iSAEC Infrastructure

    Original URL path: http://systemsbiology.columbia.edu/careers (2016-01-01)
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  • Current Job Openings | Columbia University Department of Systems Biology
    Student Seminars Affiliated PhD Programs Training Program Financial Support Individual Development Plan FAQ How to Apply Contact Us Col 4 Postdoctoral Training Opportunities for Undergraduates Infrastructure Department of Systems Biology Information Technology DSBIT High Performance Computing Data Storage Colocation and Server Hosting Virtual Server Hosting Desktop Support Pricing Staff Contact Columbia Genome Center Genome Sequencing and Analysis High Throughput Screening Medium Throughput Screening People Software Overview Software List Careers Contact Us Search News News Publications Events People Site Search Search Systems Biology Home Columbia University Department of Systems Biology Columbia University Medical Center Home About Careers Careers Current Job Openings About Overview News Events Careers Current Job Openings Contact Us Currently there are no jobs listings Please visit again soon Research Columbia Genome Center Center for Computational Biology Bioinformatics C2B2 Center for Multiscale Analysis of Genomic Cellular Networks MAGNet Library of Integrated Network Based Cellular Signatures LINCS Cancer Target Discovery Development Center CTD2 Center for Topology of Cancer Evolution and Heterogeneity International Serious Adverse Event Consortium iSAEC Infrastructure Genome Sequencing and Analysis High Throughput Screening Medium Throughput Screening Information Technology DSBIT Education Training Graduate Education Postdoctoral Training About the Department News Events Contact Careers People Software Columbia University Medical Center Columbia University Columbia University Medical Center 2015 Columbia University Medical Center Columbia University Department of Systems Biology Irving Cancer Research Center 1130 St Nicholas Avenue New York NY 10032 212 851 5208 Overview News Events Col 2 Careers Current Job Openings Contact Us About Our Research Accomplishments Publications Supporting the Systems Biology Community Research Centers Center for Computational Biology and Bioinformatics C2B2 Faculty Columbia Genome Center Genome Sequencing and Analysis Getting Started Defining Your Experiment Submitting Your Samples Data Analysis Pricing Frequently Asked Questions High Throughput Screening Automation Detection Microscopy Screening Libraries Informatics Policies Medium Throughput Screening NYSTEM Stem Cell

    Original URL path: http://systemsbiology.columbia.edu/current-job-openings (2016-01-01)
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  • Contact Us | Columbia University Department of Systems Biology
    Biology Home Columbia University Department of Systems Biology Columbia University Medical Center Home Contact Us About Overview News Events Careers Current Job Openings Contact Us The Columbia University Department of Systems Biology is based at Columbia University Medical Center located in the Washington Heights neighborhood of New York City Our faculty are located at CUMC and at the main campus of Columbia University To find specific faculty members or other members of the department please visit People Department of Systems Biology Columbia University Department of Systems Biology Irving Cancer Research Center 1130 St Nicholas Avenue 8th Floor New York NY 10032 General Inquiries 212 851 5208 Queries about PhD Education education c2b2 columbia edu Columbia Genome Center more information JP Sulzberger Columbia Genome Center Russ Berrie Medical Science Pavilion 1150 St Nicholas Avenue New York NY 10032 For all queries regarding genome sequencing data analysis high throughput screening or high content microscopy please contact us at genome columbia edu Advanced Research Computing Services ARCS more information Interim Director Orlando Aquino oa2134 cumc columbia edu Center for Multiscale Analysis of more information Genomic and Cellular Networks MAGNet Scientific Matters Aris Floratos af2202 cumc columbia edu Administrative Matters Darren Averett dja2116 cumc columbia edu Research Columbia Genome Center Center for Computational Biology Bioinformatics C2B2 Center for Multiscale Analysis of Genomic Cellular Networks MAGNet Library of Integrated Network Based Cellular Signatures LINCS Cancer Target Discovery Development Center CTD2 Center for Topology of Cancer Evolution and Heterogeneity International Serious Adverse Event Consortium iSAEC Infrastructure Genome Sequencing and Analysis High Throughput Screening Medium Throughput Screening Information Technology DSBIT Education Training Graduate Education Postdoctoral Training About the Department News Events Contact Careers People Software Columbia University Medical Center Columbia University Columbia University Medical Center 2015 Columbia University Medical Center Columbia University Department of Systems Biology Irving

    Original URL path: http://systemsbiology.columbia.edu/contact (2016-01-01)
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