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  • Duke University Center for Microbial Pathogenesis
    in clinical research and certification in clinical tropical medicine He is currently an assistant professor at Duke University in the division of infectious diseases Funded by a K23 Award from the National Institutes of Health he has published more than 35 peer reviewed original manuscripts in his current area of research interest staphylococcus pathogenesis He was recently awarded the Junior Physician Investigator Award by the American Federation of Medical Research the ICAAC Young Investigator Award and the Glaxo SmithKline Junior Faculty Award In addition he serves on the the editorial board for the journal Virulence His research interests focus on the question What makes some patients with bacteremia do poorly while others do well In order to approach this question he has generated and continues to generate large prospective cohorts of patients with bacteremia due to gram positive S aureus and gram negative enterobacteriacea organisms In addition to clinical data the corresponding bloodstream isolate and patient DNA and serum are being catalogued from these patients His immediate research objective is to identify important determinants of poor clinical outcome among patients with both gram positive S aureus and gram negative enterobacteriacea bacteremia utilizing a large cohort of well characterized patients corresponding

    Original URL path: http://mgm.duke.edu/microbial/bacteriology/fowler/bio.htm (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    Vance Fowler Jr MD MHS Professor Department of Medicine Division of Infectious Diseases biography publications website Lab members Pam Brown RN 684 4487 0212 Hospital South Kimberly Cozart 684 4487 0212 Hospital South Hitesh Dehsmukh 684 4487 0212 Hospital South

    Original URL path: http://mgm.duke.edu/microbial/bacteriology/fowler/lab.htm (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    Jr Native Valve Endocarditis due to Coagulase Negative Staphylococci Report of 99 episodes from the International Collaboration on Endocarditis Merged Database Clinical Infectious Diseases 2004 39 1527 1530 Fowler VG Jr Justice A Moore C Benjamin D Campbell S Woods CW Reller LB Corey GR Day NPJ Peacock SJ Risk Factors For Hematogenous Complications of Intravascular Catheter Associated Staphylococcus aureus Bacteremia Clinical Infectious Diseases 2005 40 695 703 Fowler VG Jr Miro JM Hoen B Cabell CH Abrutyn E Rubinstein E Corey GR Spelman D Bradley SF Barsic B Pappas PA Anstrom KJ Wray D Fortes CQ Anguera I Athan E Jones P van der Meer JTM Elliott TSJ Levine DP and Bayer AS Staphylococcus aureus Endocarditis throughout the World A Consequence of Medical Progress From the International Collaboration on Endocarditis Prospective Cohort Study JAMA 2005 293 3012 3021 Selected as one of the top 10 Papers in Infectious Diseases for the year at the 43rd Annual IDSA Meeting Oct 2005 Miro J Cabell C Olaison L Hoen B Eykyn S Raoult D Chen A Woods CW Abrutyn E Wang A Corey GR and Fowler VG Jr Staphylococcus aureus Infective Endocarditis Report from the ICE Investigators Clinical Infectious Diseases 2005 41 507 514 Fowler VG Jr Boucher HW Corey GR Abrutyn E Karchmer AW Rupp ME Levine DP Chambers HF Tally FP Vigliani G Cabell CH Link AS DeMeyer I Filler SG Zervos M Cook P Parsonnet J Bernstein JM Price CS Forrest G Fatkenheuer G Gareca M Rehm SJ Brodt HR Tice A Cosgrove SE Daptomycin versus Standard Therapy for Staphylococcus aureus Bacteremia and Endocarditis New England Journal of Medicine 2006 7 653 665 Stryjewski ME Szczech LA Benjamin DK Inrig JK Kanafani ZA Engemann JJ Chu VH Reller LB Corey GR and Fowler VG Jr Use of Vancomycin or First Generation Cephalosporins in the Treatment of Hemodialysis dependent Patients with Methicillin Susceptible Staphylococcus aureus Bacteremia Clinical Infectious Diseases 2007 44 190 196 Aksoy O Sexton DJ Wang A Pappas PA Kourany W Chu VH Fowler VG Jr Woods CW Engemann JJ Corey GR Harding BS Cabell CH Early Surgery in Patients with Infective Endocarditis A Propensity Score Analysis Clinical Infectious Diseases 2007 44 364 372 Kanafani Z Federspiel JJ and Fowler VG Jr Infective Endocarditis Caused by Daptomycin Resistant Enterococcus faecalis Scandanavian Journal of Infectious Diseases 2007 39 75 77 Yongsunthon R Fowler VG Jr Lower BH Vellano FP Reller LB Corey GR Alexander E and Lower S Correlation between fundamental binding forces and clinical prognosis of Staphylococcus aureus infections of medical implants Langmuir 2007 23 2289 2292 Wang A Athan E Pappas PA Fowler VG Jr Olaison L Pare C Almirante B Munoz P Rizzi M Naber C Logar M Tattevin P Iarussi DL Selton Suty C Braun Jones S Casabe J Morris A Corey GR and Cabell CH Contemporary Clinical Profile and Outcome of Prosthetic Valve Endocarditis JAMA 2007 297 1354 1361 Fowler VG Jr Nelson CL McIntyre LM Kreiswirth BN Monk A Archer GL Federspiel

    Original URL path: http://mgm.duke.edu/microbial/bacteriology/fowler/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Photo Gallery Other Photos Duke PhD Hooding Ceremony May 2009 Left to right Robert Bastidas Raphael Valdivia Laura Fuhrman Kris Spaeth Doug Marchuk Amy Akers and Joe Heitman Previous Next

    Original URL path: http://mgm.duke.edu/photos/other/image7.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Photo Gallery Other Photos Members of the Duke Medical Alumni Association honor John Perfect MD with the Distinguished Faculty Award at a luncheon on October 15 2010 Previous Next

    Original URL path: http://mgm.duke.edu/photos/other/image11.html (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    completed internal medicine residency clinical infectious disease fellowship and medical microbiology fellowship at Duke University Medical Center Her clinical interests are in the treatment of infections in transplant recipients and her research is clinically based She is a faculty member of the Duke Clinical Research Institute and is currently funded by the National Institutes of Health to study the prevention and diagnosis of fungal infections particularly in the solid organ and stem cell transplant populations One such ongoing investigation is a clinical trial to assess the safety of aerosolized amphotericin β lipid complex as prophylaxis for fungal disease in patients undergoing hematopoietic stem cell transplantation She has also collaborated with other centers to validate the galactomannan assay for the diagnosis of invasive aspergillosis an assay for the detection of 1 3 βD glucan for the diagnosis of multiple fungal pathogens as well as a probe using peptide nucleic acid fluorescent in situ hybridization for the identification of Candida albicans directly from blood culture bottles that show yeast on Gram stain She has served as the principal investigator at Duke for several multicenter trials investigating antifungal agents Dr Alexander has lectured nationally and internationally on fungal infections and has authored numerous

    Original URL path: http://mgm.duke.edu/microbial/mycology/alexander/bio.htm (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    Assistant Professor of Medicine Director Transplant Infectious Disease Services Head Clinical Mycology Laboratory biography publications website Lab members Rachel Addison MT ASCP MPH 118 CARL 668 5006 addis003 mc duke edu Emma Costea RN 118 CARL 668 0789 coste005 mc

    Original URL path: http://mgm.duke.edu/microbial/mycology/alexander/lab.htm (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    Reller LB Kaye KS Mortality associated with Burkholderia cepacia genomovar III among a cohort of patients with bacteremia under revision Paya C Humar A Dominguez E Washburn WK Blumberg E Alexander B Freeman R Heaton N Pescovitz M Efficacy and safety of valganciclovir vs oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients Am J of Transplantation 2004 4 4 611 620 Zaas AK Boyce M Schell W Alexander Lodge B Miller JL Perfect JR Risk of fungemia due to Rhodotorula and antifungal susceptibility testing of Rhodotorula isolates J Clin Micro 2003 41 11 5233 5235 Woods CW Bressler AM LiPuma JJ Alexander BD Clements DA Weber DJ Moore CM Reller LB Kaye KS Virulence associated with outbreak related strains of Burkholderia cepacia complex among a cohort of patients with bacteremia Clin Infect Dis 2004 38 1243 50 Alexander Lodge B Ashley ED Steele MP Perfect JR Aspergillus fumigatus empyema arthritis and calcaneal osteomyelitis in a lung transplant patient successfully treated with posaconazole J Clin Micro 2004 42 3 1376 1378 Boivin G Goyette N Gilbert C Roberts N Macey K Paya C Pescovitz M Humar A Dominguez E Washburn K Blumberg E Alexander B Freeman R Heaton N Covington E Absence of CMV resistance mutations following valganciclovir prophylaxis in a prospective multicenter study in solid organ transplant recipients J Infect Dis 2004 2004 189 1615 1618 Humar A Paya C Pescovitz M Dominguez E Washburn K Blumberg E Alexander B Freeman R Heaton N Mueller B Clinical utility of CMV viral load testing for predicting CMV disease in D R solid organ transplant recipients Am J of Transplantation 2004 4 644 649 Freeman R Paya C Pescovitz M Humar A Dominguez E Washburn K Blumberg E Alexander B Heaton N and the Valganciclovir Solid Organ Transplant Study Group Risk factors for cytomegalovirus viremia and disease developing after prophylaxis in high risk solid organ transplant recipients Transplantation 2004 78 12 1765 1773 Wiltshire H Hirankarn S Farrell C Paya C Pescovitz M Humar A Dominguez E Washburn K Blumberg E Alexander B Freeman R Heaton N and the Valganciclovir Solid Organ Transplant Study Group Pharmacokinetic profile of oral ganciclovir after its oral administration and from its prodrug valganciclovir in solid organ transplant recipients Clin Pharmacokinetics 2005 44 5 495 507 Wilson M Joyce M Hall L Reller L Roberts G Hall G Alexander B Procop G Mulitcenter evaluation of a Candida albicans PNA FISH Probe for blood cultures that grow yeasts J Clin Micro 2005 43 6 2909 12 Husain S Munõz P Forrest G Alexander B Somani J Brennan K Wagener M Singh N Infections due to Scedosporium apiospermum and Scedosporium prolificans in transplant recipients clinical characteristics and impact of antifungal agent therapy on outcome Clin Infect Dis 2005 40 89 99 Upton A Gugel A Leisenring W Limaye A Alexander B Hayden R Marr K Reproducibility of low galactomannan enzyme immunoassay index values tested in multiple laboratories J Clin Micro 2005 In press Ostrosky Zeichner

    Original URL path: http://mgm.duke.edu/microbial/mycology/alexander/pubs.htm (2014-06-13)
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