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  • Duke University Department of Molecular Genetics & Microbiology
    lingfeng meng duke edu Research Interests Nervous systems are generally composed of neurons and glia Although glia are as numerous as neurons in vertebrate research on neurons marched on while glia languished In C elegans RME neurons form gap junctions with six glial cells the GLR cells which is an ideal model to study the relationship between neurons and glia in vivo Combined with tools of genetic and single synapse

    Original URL path: http://mgm.duke.edu/faculty/yan/lab/meng.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    against Foot and Mouth Disease Virus for in process control estimation of antigen in vaccine manufacturing at Indian Immunologicals limited India By the end of my graduate program in 2010 I got the opportunity to develop serological and non serological techniques for Bloodmeal analysis of mosquito at the National Institute of Malaria Research India My immense interest in Infectious Diseases and Virology made me delve further into this field With this notion I moved to Georgetown University and joined the laboratory of Radhakrishnan Padmanabhan as a Research Scholar Here my research focused on site specific labeling of dengue viral proteins using a flourophore ligase and on the mechanism of various chemical inhibitors targeting different viral proteins Then I steered my journey to Madison WI where I found myself in a more exciting ambiance As a research specialist in the laboratory of Nathan Sherer at the McArdle Laboratory for Cancer Research University of Wisconsin I studied the viral and cellular determinants that underlie a species specific block to HIV 1 replication in mouse cells Viruses display remarkable specificity in both the host species and the cell types that they infect Understanding this specificity reveals insight into the basic host components that

    Original URL path: http://mgm.duke.edu/faculty/horner/lab/aligeti.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    caused by mutation of certain threonine biosynthetic enzymes in both S cerevisiae and C albicans In 2010 I joined the Heitman group in collaboration with Sheldon Pinnell Duke Department of Dermatology to focus on novel strategies for the treatment of dermatophytic fungal infections Dermatophytic infections such as those caused by Trichophyton species are the most common cause of superficial mycoses worldwide yet the limited range of therapeutic drugs available are fraught with problems such as high price toxicity and or poor efficacy Publications Kingsbury J M Sen N D Heitman J Cardenas M E Endolysosomal membrane trafficking complexes drive nutrient dependent TORC1 signaling to control cell growth in Saccharomyces cerevisiae Submitted to Genetics Gioti A Nystedt B Li W Xu J Andersson A Averette A F Munch K Wang X Kappauf C Kingsbury J M Kraak B Walker L A Johansson H J Holm T Lehtio J Stajich J E Mieczkowski P Kahmann R Kennell J C Cardenas M E Lundeberg J Saunders C W Boekhout T Dawson T L Munro C A de Groot P W Butler G Heitman J Scheynius A 2013 Genomic insights into the atopic eczema associated skin commensal yeast Malassezia sympodialis MBio 4 e00572 00512 Kingsbury J M Heitman J Pinnell S R 2012 Calcofluor white combination antifungal treatments for Trichophyton rubrum and Candida albicans PLoS One 7 e39405 Kingsbury J M McCusker J H 2010 Homoserine toxicity in Saccharomyces cerevisiae and Candida albicans homoserine kinase thr1 mutants Eukaryotic Cell 9 717 728 Featured as Eukaryotic Cell Article of Significant Interest and June 2010 Microbe Magazine Journal Highlights Kingsbury J M McCusker J H 2010 Fungal homoserine kinase thr1 mutants are attenuated in virulence and die rapidly upon threonine starvation and serum incubation Eukaryotic Cell 9 729 737 Featured as Eukaryotic Cell Article of Significant

    Original URL path: http://mgm.duke.edu/faculty/cardenas/lab/kingsbury.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    of his graduate career He joined the Rawls lab in 2012 where he is finishing his thesis project on microbial control of host transcription When away from the bench Jim enjoys spending his time hiking canoeing or playing tennis Publications Sec14 Like PITPs Couple Lipid Metabolism with Phosphoinositide Synthesis to Regulate Golgi Functionality Mousley CJ Davison JM Bankaitis VA Subcell Biochem 2012 59 271 87 Devising powerful genetics biochemical and

    Original URL path: http://mgm.duke.edu/faculty/rawls/lab/davison.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Grohman JK Gorelick RJ Lickwar CR Lieb JD Bower BD Znosko BM Weeks KM Science 2013 Apr 12 340 6129 190 5 Epub 2013 Mar 7 Genome wide protein DNA binding dynamics suggest a molecular clutch for transcription factor function Lickwar CR Mueller F Hanlon SE McNally JG Lieb JD Nature 2012 Apr 11 484 7393 251 5 The Set2 Rpd3S pathway suppresses cryptic transcription without regard to gene length

    Original URL path: http://mgm.duke.edu/faculty/rawls/lab/lickwar.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    loci associated with obesity however the mechanisms of action by which associated loci influence obesity are largely unknown The central goal of my research in the Rawls lab is to investigate the role of novel genes implicated in obesity and to identify how these loci act to increase susceptibility and disease progression To this end we are using high resolution in vivo imaging and functional genetics in zebrafish Grant Support 2013 2014 Plexin D1 Regulates Visceral Adipose Tissue Growth in Zebrafish American Heart Association Postdoctoral Fellowship 13POST16930097 2011 2013 In Vivo Analysis of Adipose Tissue Morphogenesis in Zebrafish American Heart Association Postdoctoral Fellowship 11POST7360004 Publications Minchin JE Williams VC Hinits Y Low SH Tandon P Fan CM Rawls JF and Hughes SM 2013 Oesophageal and sternohyal muscle fibres are novel Pax3 dependent migratory somite derivatives essential for ingestion Development 140 2972 84 McMenamin SK Minchin JE Gordan TN Rawls JF and Parichy DM 2013 Dwarfism and increased adiposity in the growth hormone 1 mutant vizzini Endocrinology 154 1476 87 Equal Contributions Minchin JE and Rawls JF 2011 In vivo analysis of white adipose tissue in zebrafish Methods in Cell Biology 105C 63 86 Valasek P Theis S DeLaurier A Hinits

    Original URL path: http://mgm.duke.edu/faculty/rawls/lab/minchin.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Photo Gallery Other Photos John R Perfect MD poses with his family at the Duke Medical Alumni Association luncheon on October 15 2010 Previous Next

    Original URL path: http://mgm.duke.edu/photos/other/image12.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    C 27710 Phone 919 664 2857 Fax 919 684 2790 Email daphne ezer duke edu I am a junior who is double majoring in computer science and biology I am interested in systems biology in particular in epigenetics and gene

    Original URL path: http://mgm.duke.edu/faculty/dietrich/lab/ezer.html (2014-06-13)
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