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  • Duke University Department of Molecular Genetics & Microbiology
    in 2004 under the direction of Dr Radek Skoda He then spent two years at the Harvard Medical School Department of Genetics as a postdoctoral fellow with Dr William Dietrich before joining Dr Michael Starnbach s lab in the Department of Microbiology and Molecular Genetics Dr Coers was awarded a Young Scientist Award from the Swiss Society of Hematology in 2003 a Jane E Raulston Award from the Chlamydia Basic

    Original URL path: http://mgm.duke.edu/news/coers.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Department of Molecular Genetics and Microbiology Inositol is abundant in the human brain and in the fluid that bathes it cerebral spinal fluid which may be why this fungus has a predilection to infect the brain and cause meningitis Heitman said It has the machinery to efficiently move sugar molecules inside of its cells and thrive The findings on Cryptococcus genes were published online this week in the inaugural issue of mBio a new open access microbiology journal This specialized brain attack likely occurred because these fungi adapted to grow on plants in the wild which also are abundant in inositol said lead author Chaoyang Xue PhD formerly a postdoctoral research associate in the Heitman lab and now an assistant professor at the Public Health Research Institute at the University of Medicine and Dentistry of New Jersey In fact this pathogenic yeast has more inositol transporters than all other fungi we have compared it to in the fungal kingdom based on what we know from genome research The team of researchers discovered that inositol stimulates Cryptococcus to sexually reproduce A connection between the high concentration of free inositol and fungal infection in the human brain is suggested by our studies Xue said Establishing such a connection could open up a new way to control this deadly fungus Cryptococcus love for sugar may also be a fungal Achilles heel Heitman said Now scientists may be able to target the fungi by developing ways to put them on the fungal equivalent of an Atkin s low carbohydrate diet so they will stop multiplying He said researchers could use the new findings to devise different types of strategies to block Cryptococcus infections These studies will be reported in the inaugural issue of the journal mBio which will be launched in May by the

    Original URL path: http://mgm.duke.edu/news/heitman_4.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Thursday April 8 2010 8 55am Bryan Cullen PhD Duke Opening Remarks 9 00am Robert H Silverman PhD Cleveland Clinic Implications for the Human Retrovirus XMRV in Prostate Cancer 9 45am Paul Bieniasz PhD The Rockefeller University Tethering Virions Battles at the Cell Surface Between Enveloped Viruses and Their Hosts 10 30am Break 11 00am Ann Palmenberg PhD University of Wisconsin Madison What We Learned from Sequencing Every Human Rhinovirus

    Original URL path: http://mgm.duke.edu/news/human_viruses.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    and mentoring and for his exemplary commitment to the education of graduate students within Basic Science Departments and Graduate Training Programs of the School of Medicine The award is named for Gordon G Hammes PhD Professor of Biochemistry and University Distinguished Professor who served as Vice Chancellor for Academic Affairs from 1991 through 1998 During his tenure as Vice Chancellor Professor Hammes led a number of major initiatives to improve

    Original URL path: http://mgm.duke.edu/news/marchuk.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    member of EMBO He has received many awards including the Swiss Bridge Prize Award for Cancer Research in 2001 and again in 2009 the Louis Jeantet Prize for Medicine in 2007 and the Novartis medal and prize from the Biochemical Society in 2008 Stephen C West PhD Cancer Research UK London Research Institute Clare Hall Laboratories South Mimms Herts EN6 3LD UK stephen west cancer org uk Seminar TBA 4 00pm 5 15pm 103 Bryan Research Building Reception to follow lecture Download flyer PDF 180KB The annual McGinnis Memorial Lecture was established by the staff and students of the Departments of Microbiology and Immunology in 1979 to honor the memory of James William McGinnis Jr Jim was born March 13 1951 in Greensboro N C He grew up in Cary graduated from Phillips Academy Andover Mass received a B S degree in Chemistry from Stanford University in 1973 completed the first year of medical school at Duke transferred to the Department of Microbiology and Immunology and was a doctoral candidate here at the time of his death March 11 1978 in a canoeing accident His research involved in vitro translation and RNase III processing of avian tumor virus RSV RNA

    Original URL path: http://mgm.duke.edu/news/mcginnis.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    their records of scientific achievement and original contributions that have advanced microbiology The Academy serves as a resource to governmental agencies industry ASM and the larger scientific and lay communities by convening colloquia to address critical issues in microbiology Through its sponsorship of the American College of Microbiology the Academy certifies outstanding microbiologists and immunologists in clinical and industrial specialties and accredits postdoctoral training programs in clinical and public health

    Original URL path: http://mgm.duke.edu/news/robertson.html (2014-06-13)
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  • Duke University Center for Microbial Pathogenesis
    at NSF for more than 22 years and was considered the patron saint of genetics and friend of many geneticists She was primarily interested in the science and because of this interest championed the funding of the genomic sequencing of Arabidopsis and research in Drosophila Nasser was especially supportive of young scientists particularly those who were beginning their careers and those who were pursuing new areas of genetic inquiry O Meara works in the laboratory of J Andrew Alspaugh MD Associate Professor in the Department of Medicine Division of Infectious Diseases Project Summary The Rim101 transcription factor regulates capsule iron and virulence in C neoformans In order for Cryptococcus neoformans to cause disease it must be able to respond to the hostile environment of a human host Towards this end C neoformans integrates signals from two conserved signaling cascades the cAMP PKA and RIM pathways to activate the Rim101 transcription factor We recently demonstrated that PKA phosphorylation is required for Rim101 truncation and localization to the nucleus New deep RNA sequencing data provides evidence that Rim101 shares extensive downstream targets with PKA further demonstrating the novel interaction between CnRim101 and PKA When examining the role of Rim101 in mouse models

    Original URL path: http://mgm.duke.edu/microbial/news/omeara_2.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    at Chapel Hill will organize the Federation of American Societies for Experimental Biology FASEB conference as co chair and chair respectively As with previous conferences the 2011 FASEB Microbial Pathogenesis meeting will showcase the breadth and depth of the discipline with seminars from leading scientists in the field This long standing meeting bridges all disciplines of microbial pathogenesis including bacteriology virology parasitology mycology and immunology Its value to the scientific community is unique and cross disciplinary stimulating integration of multiple approaches Historically this meeting has brought leading young investigators to the attention of the broader community and has promoted new directions including development and application of heterologous host models analysis of new and emerging pathogens and novel appreciation of the diversity of host defenses As in past meetings the organizers seek to actively involve leading journal editors from the field including investigators who serve as editors and editorial board members and professional editors for Nature Nature Reviews Microbiology Cell Host Microbe PLoS Pathogens Molecular Microbiology mBio Eukaryotic Cell Infection Immunity the Journal of Bacteriology and the Journal of Virology and Virulence This forum effectively brings scientists and editors together to promote the dissemination of scientific advances and also provide insight

    Original URL path: http://mgm.duke.edu/news/faseb.html (2014-06-13)
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