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  • Duke University Department of Molecular Genetics & Microbiology
    HIV 1 infected individuals PLoS Pathog 2010 Feb 26 6 2 e1000781 Fellay J Thompson AJ Ge D Gumbs CE Urban TJ Shianna KV Little LD Qiu P Bertelsen AH Watson M Warner A Muir AJ Brass C Albrecht J Sulkowski M McHutchison JG Goldstein DB ITPA gene variants protect against anaemia in patients treated for chronic hepatitis C Nature 2010 Mar 18 464 7287 405 8 Heinzen EL Need AC Hayden KM Chiba Falek O Roses AD Strittmatter WJ Burke JR Hulette CM Welsh Bohmer KA Goldstein DB Genome wide scan of copy number variation in late onset Alzheimer s disease J Alzheimers Dis 2010 Jan 19 1 69 77 Fellay J Ge D Shianna KV Colombo S Ledergerber B Cirulli ET Urban TJ Zhang K Gumbs CE Smith JP Castagna A Cozzi Lepri A De Luca A Easterbrook P Günthard HF Mallal S Mussini C Dalmau J Martinez Picado J Miro JM Obel N Wolinsky SM Martinson JJ Detels R Margolick JB Jacobson LP Descombes P Antonarakis SE Beckmann JS O Brien SJ Letvin NL McMichael AJ Haynes BF Carrington M Feng S Telenti A Goldstein DB NIAID Center for HIV AIDS Vaccine Immunology CHAVI Common genetic variation and the control of HIV 1 in humans PLoS Genet 2009 Dec 5 12 e1000791 Idaghdour Y Czika W Shianna KV Lee SH Visscher PM Martin HC Miclaus K Jadallah SJ Goldstein DB Wolfinger RD Gibson G Geographical genomics of human leukocyte gene expression variation in southern Morocco Nat Genet 2010 Jan 42 1 62 7 Yoon W Ma BJ Fellay J Huang W Xia SM Zhang R Shianna KV Liao HX Haynes BF Goldstein DB NIAID Center for HIV AIDS Vaccine Immunology A polymorphism in the HCP5 gene associated with HLA B 5701 does not restrict HIV 1 in vitro AIDS 2010 Jan 2 24 1 155 7 Chaudhry AS Urban TJ Lamba JK Birnbaum AK Remmel RP Subramanian M Strom S You JH Kasperaviciute D Catarino CB Radtke RA Sisodiya SM Goldstein DB Schuetz EG CYP2C9 1B promoter polymorphisms in linkage with CYP2C19 2 affect phenytoin autoinduction of clearance and maintenance dose J Pharmacol Exp Ther 2010 Feb 332 2 599 611 Need AC Goldstein DB Next generation disparities in human genomics concerns and remedies Trends Genet 2009 Nov 25 11 489 94 Manolio TA Collins FS Cox NJ Goldstein DB Hindorff LA Hunter DJ McCarthy MI Ramos EM Cardon LR Chakravarti A Cho JH Guttmacher AE Kong A Kruglyak L Mardis E Rotimi CN Slatkin M Valle D Whittemore AS Boehnke M Clark AG Eichler EE Gibson G Haines JL Mackay TF McCarroll SA Visscher PM Finding the missing heritability of complex diseases Nature 2009 Oct 8 461 7265 747 53 Review Urban TJ Weintrob AC Fellay J Colombo S Shianna KV Gumbs C Rotger M Pelak K Dang KK Detels R Martinson JJ O Brien SJ Letvin NL McMichael AJ Haynes BF Carrington M Telenti A Michael NL Goldstein DB CCL3L1 and HIV AIDS susceptibility Nat

    Original URL path: http://mgm.duke.edu/faculty/goldstein/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    focused on the plasma membrane ATPase and cycloheximide resistant temperature sensitive lethal mutations of Saccharomyces cerevisiae Post doctoral work followed first with Masayasu Nomura U C Irvine focusing on genetic analysis of RNA polymerase I of S cerevisiae and subsequently with Ron Davis Stanford focusing on both genomics and the development of S cerevisiae as a model pathogen Dr McCusker moved to Duke in 1995 and is a member of

    Original URL path: http://mgm.duke.edu/faculty/mccusker/bio.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Faculty and Research John H McCusker PhD Associate Professor research biography lab members publications lab website Lab members John McCusker Associate Professor Stanislav Kozmin Research Associate Senior

    Original URL path: http://mgm.duke.edu/faculty/mccusker/lab.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    2009 A multispecies based taxonomic microarray reveals interspecies hybridization and introgression in Saccharomyces cerevisiae FEMS Yeast Res 9 143 152 Epub 2008 Nov 24 Abstract Sinha H L David R C Pascon S Clauder Munster S Krishnakumar M Nguyen G Shi J Dean R W Davis P J Oefner J H McCusker and L M Steinmetz 2008 Sequential elimination of major effect contributors identifies additional quantitative trait loci conditioning high temperature growth in yeast Genetics 180 3 1661 1670 Epub 2008 Sep 9 Abstract Kingsbury J M and J H McCusker 2008 Threonine biosynthetic genes are essential in Cryptococcus neoformans Microbiology 154 2767 2775 Abstract Wei W J H McCusker R W Hyman T Jones Y Ning Z Cao Z Gu D Bruno M Miranda M Nguyen J Wilhelmy C Komp R Tamse X Wang P Jia P Luedi P J Oefner L David F S Dietrich Y Li R W Davis and L M Steinmetz 2007 Genome sequencing and comparative analysis of Saccharomyces cerevisiae strain YJM789 Proc Natl Acad Sci USA 104 31 12825 12830 Epub 2007 Jul 25 Abstract Kingsbury J M A L Goldstein and J H McCusker 2006 The role of nitrogen and carbon transport regulation and metabolism genes for Saccharomyces cerevisiae survival in vivo Eukaryotic Cell 5 816 824 Abstract Sinha H B P Nicholson L S Steinmetz and J H McCusker 2006 Complex genetic interactions in a quantitative trait locus PLoS Genetics 2 2 e13 Abstract Pascon R C T M Ganous J M Kingsbury G M Cox and J H McCusker 2004 Cryptococcus neoformans methionine synthase expression analysis and requirement for virulence Microbiology 150 3013 3023 Abstract Kingsbury J M Z Yang T M Ganous G M Cox and J H McCusker 2004 A novel chimeric spermidine synthase saccharopine dehydrogenase SPE3 LYS9 gene

    Original URL path: http://mgm.duke.edu/faculty/mccusker/pubs.htm (2014-06-13)
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  • The McCusker Lab
    The McCusker laboratory works with the yeast Saccharomyces cerevisiae using genetic techniques to study three areas novel antifungal drug targets aging chronological life span and quantitative genetics

    Original URL path: http://mgm.duke.edu/faculty/mccusker/lab/ (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Biology and Chemistry at Montclair State University As an undergraduate I worked in the laboratories of David Zacharias at the Whitney Laboratory for Marine Bioscience UF in 2007 Ashley Chi at Duke in 2008 and Nevan Krogan at UCSF in 2009 I earned my BS in 2010 and came to Duke through the University Program in Genetics and Genomics that same year I am currently studying protein RNA dynamics in

    Original URL path: http://mgm.duke.edu/faculty/keene/lab/simone.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    biotech company Seqwright My research background varies from an ecological study of an invasive apple snail species to population genetics survey of a Ugandan rat population Perhaps it is not surprising that my scientific interests focus on locating those ecologically and or evolutionary important variations in phenotypes or behaviors and locating the variations at the regulatory genetic and developmental level that lead to those variations My passion remains in ecology

    Original URL path: http://mgm.duke.edu/faculty/petes/lab/moore.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    corn took me to Dartmouth College in Hanover NH After realizing my future did not involve plants or fruit flies I joined Dr George O Toole s laboratory and studied c di GMP mediated suppression of swarming motility in Pseudomonas aeruginosa Being a member of the O Toole laboratory was an invaluable experience for me and inspired me to continue my studies in microbial pathogenesis in graduate school I chose

    Original URL path: http://mgm.duke.edu/faculty/valdivia/lab/snavely.html (2014-06-13)
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