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  • Duke University Department of Molecular Genetics & Microbiology
    Williams J S Li Y C Clark A B Cho J E Kunkel T A Pommier Y and Jinks Robertson S 2011 Mutagenic processing of ribonucleotides in DNA by yeast topoisomerase I Science 24 1561 1564 Kim N and Jinks Robertson S 2010 Abasic sites in the transcribed strand of yeast DNA are removed by transcription coupled necleotide excision repair Mol Cell Bio 30 3206 3215 Mitchel K Zhang H Welz Voegele C and Jinks Robertson S 2010 Molecular structures of crossover and noncrossover intermediates during gap repair in yeast Implications for recombination Mol Cell 38 211 222 Mudrak S V Welz Voegele C and Jinks Robertson S 2009 The polymerase eta translesion synthesis DNA polymerase acts independently of the mismatch repair system to limit mutagenesis caused by 7 8 dihydro 8 oxoguanine in yeast Mol Cell Biol 29 5316 5326 Kim N and Jinks Robertson S 2009 dUTP incorporation into genomic DNA is linked to transcription in yeast Nature 459 1150 1153 Lehner K and Jinks Robertson S 2009 The mismatch repair system promotes DNA polymerase zeta dependent translesion synthesis in yeast Proc Natl Acad Sci USA 106 5749 5754 Welz Voegele C and Jinks Robertson S 2008 Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast Genetics 179 1251 1262 Stone J E Ozbirn R G Petes T D and Jinks Robertson S 2008 Role of proliferating cell nuclear antigen interactions in the mismatch repair dependent processing of mitotic and meiotic recombination intermediates in yeast Genetics 178 1221 1236 Abdulovic A L Minesinger B K and Jinks Robertson S 2008 The effect of sequence context on spontaneious Polzeta dependent mutagenesis in Saccharomyces cerevisiae Nucleic Acids Res 36 2082 2093 Welz Voegele C and Jinks Robertson S 2008 Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast Genetics 179 1251 1262 Abdulovic A L Minesinger B K and Jinks Robertson S 2007 Identification of a strand related bias in the PCNA mediated bypass of spontaneous lesions by yeast Poleta DNA Repair Amst 6 1307 1318 Kow Y W Bao G Reeves J W Jinks Robertson S and Crouse G F 2007 Oligonucleotide transformation of yeast reveals mismatch repair complexes to be differentially active on DNA replication strands Proc Natl Acad Sci USA 104 11352 11357 Abdulovic A L Kim N and Jinks Robertson S 2006 Mutagenesis and the three R s in yeast DNA Repair 5 409 421 Abdulovic A L and Jinks Robertson S 2006 The in vivo characterization of translesion synthesis across UV induced lesions in Saccharomyces cerevisiae novel insight into Polζ and Polη dependent frameshift mutagenesis Genetics 172 1487 1498 Sabbioneda S Minesinger B K Giannattasio M Plevani P Muzi Falconi M and Jinks Robertson S 2005 The 9 1 1 checkpoint clamp physically interacts with Polζ and is partially required for spontaneous Polζ dependent mutagenesis in Sacchaormyces cerevisiae J Biol Chem 280 38657 38665 Minesinger B K and Jinks Robertson S 2005 Roles of RAD6

    Original URL path: http://mgm.duke.edu/faculty/robertson/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Deputy Director Center for Virology research biography lab members alumni publications lab website Lab members Ashley Barry Lab Research Analyst I Micah Luftig Assistant Professor Frank Cai Undergraduate Student Karyn McFadden Postdoctoral Associate Amy Hafez Graduate Student Alex Price Graduate

    Original URL path: http://mgm.duke.edu/faculty/luftig/lab.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Virology at Harvard Medical School Initially he worked in Dr Don Wiley s lab continuing the biochemical study of herpesvirus glycoproteins He crystallized the complex of HSV 1 gD and its receptor nectin 1 a structure that would be solved nine years later in the group of Dr Andrea Carfi His thesis research was in Dr Elliott Kieff s lab studying Epstein Barr virus EBV He identified the genetic requirements of NFkB activation by the viral oncoprotein latent membrane protein 1 These studies have been corroborated by others and laid the foundation for understanding the molecular basis of diverse NFkB activation pathways He followed up these studies with a proteomic analysis of the purified Epstein Barr virus enveloped particle and nucleocapsid This benchmark biochemical paper identified a number of novel virion components including a role for host cytoskeletal and chaperone proteins in the mature virion He was awarded a Ph D in Virology in 2003 Dr Luftig next joined the group of Dr Andrea Carfi in the Department of Biochemistry at the Istituto di Ricerca di Biologia Molecolare IRBM P Angeletti in Pomezia Italy outside of Rome He was awarded an EMBO Long Term Postdoctoral Fellowship for his structural studies

    Original URL path: http://mgm.duke.edu/faculty/luftig/bio.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    website Post Doctoral Fellows NAME CURRENT POSITION LOCATION Alessio Bocedi Researcher University of Rome Eleonora Forte Post Doctoral Fellow University of Utah Graduate Students NAME CURRENT POSITION LOCATION Pavel Nikitin Post Doctoral Fellow Novartis Institute for Biomedical Research Emeryville CA Undergraduate Students NAME CURRENT POSITION LOCATION Christina Chang Graduate Student University of California San Diego Lisa Grossman MD PhD Student Columbia University Jing Guo Consultant Accenture Katherine Hu Lab Technician

    Original URL path: http://mgm.duke.edu/faculty/luftig/alumni.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    M A Luftig M A 2013 Epstein Barr virus induces global changes in cellular mRNA isoform usage important for the maintenance of latency J Virol 2013 Sep 11 Epub ahead of print Abstract McFadden K Luftig M A Interplay between DNA tumor viruses and the host DNA damage response 2013 Curr Top Microbiol Immunol 371 229 57 Review Abstract Price A M J P Tourigny E Forte R E Salinas S S Dave Luftig M A 2012 Analysis of EBV Regulated Host Gene Expression Changes through Primary B Cell Outgrowth Reveals Delayed Kinetics of LMP1 Mediated NF 922B Activation J Virol 86 20 11096 106 Abstract PDF Robinson T J E Forte R E Salinas S Puri M Marengo M A Garcia Blanco Luftig M A 2012 SplicerEX A tool for the automated detection and classification of mRNA changes from conventional and splice sensitive microarray expression data RNA 18 8 1435 45 Abstract PDF Nikitin P A Luftig M A 2012 The DNA damage response in viral induced cellular transformation Br J Cancer 106 429 435 Abstract PDF Skalsky R L Corcoran D L Gottwein E Frank C L Kang D Hafner M Nusbaum J D Feederle R Delecluse H J Luftig M A Tuschl T Ohler U Cullen B R 2012 The viral and cellular microRNA targetome in lymphoblastoid cell lines PLoS Pathog 8 e1002484 Abstract PDF Forte E Salinas R Chang C Zhou T Linnstaedt S D Gottwein E Jacobs C Jima D Li Q J Dave S S Luftig M A 2012 The Epstein Barr virus induced tumor suppressor miR 34a is growth promoting in EBV infected B cells J Virol 86 6889 6898 Abstract PDF Forte E Luftig M A 2011 The role of microRNAs in Epstein Barr virus latency and lytic reactivation Microbes Infect 13

    Original URL path: http://mgm.duke.edu/faculty/luftig/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    with other cancer causing viruses and oncogenes Importantly we have established collaborations to study this response in EBV positive lymphomas and would ultimately like to define therapeutic targets based on these findings that may eradicate these cancers If you are interested in donating to our research please use any of the following methods Online https www gifts duke edu Scroll down the page to the section where you are asked

    Original URL path: http://mgm.duke.edu/faculty/luftig/donations.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Nobel laureate Phillip A Sharp at MIT Professor Garcia Blanco is an internationally recognized expert in RNA biology and is an author of more than 120 scientific publications Additionally he co founded Intronn Inc now VIRxSYS Rockville MD USA to develop a novel trans splicing RNA therapy and Veri Q Inc part of Proteome Sciences plc Cobham UK to commercialize reagents for the quality control of chemically synthesized nucleic acids

    Original URL path: http://mgm.duke.edu/faculty/garcia/bio.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Research Analyst Jing Li Research Fellow in Hematology Oncology Nicholas Barrows PhD Student Gaddiel Galarza Munoz Post Doctoral Associate Shelton Bradrick Assistant Research Professor Simardeep Nagyal Undergraduate Student Rafael Campos Graduate Student Hilary Novatt Undergraduate Student Sharon Chapman Laboratory Assistant Stacia Phillips Post Doctoral Associate Mariano Garcia Blanco Charles D Watts Professor Daneen Schaeffer Post Doctoral Fellow Holly Jakubowski Lab Manager Jason Somarelli ACS Post Doctoral Fellow Gabor Kemeny Research

    Original URL path: http://mgm.duke.edu/faculty/garcia/lab.htm (2014-06-13)
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