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  • Duke University Center for Microbial Pathogenesis
    Muller M Presber W Mitchell T G Tietz H J 2000 Assessment of genetic relatedness of vaginal isolates of Candida albicans from differenct geographical origins Int J Med Microbiol 290 97 104 McEwen J G Taylor J W Carter D Xu J Felipe M S Vilgalys R Mitchell T G Kasuga T White T Bui T Soares C M 2000 Molecular typing of pathogenic fungi Medical Mycology 38 189 197 Schonian G Forche A Tietz H J Muller M Graser Y Vilgalys R Mitchell T G Presber W 2000 Genetic structure of geographically different populations of Candida albicans Mycoses 43 51 56 Xu J Onyewu C Yoell H J Ali R Y Vilgalys R J and Mitchell T G 2001 Dynamic and heterogeneous mutations to fluconazole resistance in Cryptococcus neoformans Antimicrob Agents Chemother 45 420 427 Xu J and T G Mitchell 2002 Strain variation and clonality in Candida spp and Cryptococcus neoformans In Calderone R A and R L Cihlar eds Fungal Pathogenesis Principles and Clinical Applications Marcel Dekker New York NY pp 739 749 Xu J Luo G Vilgalys R J Brandt M E and Mitchell T G 2002 Multiple origins of hybrid strains of Cryptococcus neoformans with serotype AD Microbiology 148 203 212 Luo G and Mitchell T G 2002 Rapid identification of pathogenic fungi directly from cultures by using multiplex PCR Journal of Clinical Microbiology 40 2860 2865 Xu J and Mitchell T G 2003 Geographical differences in human oral yeast flora Clin Infect Dis 36 221 224 Xu J and Mitchell T G 2003 Comparative gene genealogical analyses of strains of serotype AD identify recombination in populations of serotypes A and D in the human pathogenic yeast Cryptococcus neoformans Microbiology 149 2147 2154 Litvintseva A P Marra R E Nielsen K Heitman J Vilgalys R and Mitchell T G 2003 Evidence of sexual recombination among Cryptococcus neoformans serotype A isolates in sub Saharan Africa Eukaryotic Cell 2 1162 1168 Steinbach W J Mitchell T G Schell W A Espinel Ingroff A Coico R F Walsh T J and Perfect J R 2003 Status of medical mycology education Medical Mycology 41 457 467 Marra R E Huang J C Fung E Nielsen K Heitman J Vilgalys R and Mitchell T G 2004 A genetic linkage map of Cryptococcus neoformans variety neoformans serotype D Filobasidiella neoformans Genetics 167 619 631 Diezmann S Cox C J Schonian G Vilgalys R J and Mitchell T G 2004 Phylogeny and evolution of medical species of Candida and related taxa a multigenic analysis Journal of Clinical Microbiology 42 5624 5635 Loftus B J et al 2005 The genome of the basidiomycetous yeast and human fungal pathogen Cryptococcus neoformans Science 307 1321 1324 Litvintseva A P Kestenbaum L Vilgalys R and Mitchell T G 2005 Comparative analysis of environmental and clinical populations of Cryptococcus neoformans Journal of Clinical Microbiology 43 556 564 Fraser J A Huang J C Pukkila Worley R Alspaugh J A Mitchell T G and Heitman J 2005 Chromosomal

    Original URL path: http://mgm.duke.edu/microbial/mycology/mitchell/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    at the University of Alabama Birmingham She entered graduate school at Yale University in the Microbiology graduate program where she worked with Dr Daniel DiMaio Her graduate research focused on human papillomavirus HPV regulation of cellular growth control pathways and also on designing strategies to eliminate HPV DNA from cervical cancer cells She received her Ph D in Microbiology from Yale in 2007 Building on her interest of virus host interactions Dr Horner joined the laboratory of Dr Michael Gale Jr at the University of Washington for her postdoctoral training in 2007 Her postdoctoral research focused on understanding innate immune regulation by hepatitis C virus HCV a global human pathogen During this time she identified the mitochondrial associated ER membrane MAM a subdomain of the ER located adjacent to mitochondria as a membrane platform that organizes innate immune signaling and also as the intracellular site of immune regulation by HCV Dr Horner s postdoctoral research was supported by the Irvington Institute Fellowship Program of the Cancer Research Institute Dr Horner joined the faculty of the Molecular Genetics Microbiology and Medicine departments at Duke University Medical Center in 2013 Her laboratory is interested in understanding the cell biology of antiviral innate

    Original URL path: http://mgm.duke.edu/faculty/horner/bio.html (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Horner PhD Assistant Professor research biography lab members publications lab website Lab members Mounavya Aligeti Associate in Research Lab Manager Allison Roder Graduate Student Nandan Gokhale Graduate Student Christine Vazquez

    Original URL path: http://mgm.duke.edu/faculty/horner/lab.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    defenses by hepatitis C virus In Chronic Hepatitis B and C Edited by C Shih World Scientific Publishing Co Singapore 2012 pp 245 270 Liu HM Loo YM Horner SM Zornetzer GA Katze MG Gale M Jr The Mitochondrial Targeting Chaperone 14 3 3epsilon Regulates a RIG I Translocon that Mediates Membrane Association and Innate Antiviral Immunity Cell Host Microbe 2012 11 5 528 37 Patel MR Loo YM Horner SM Gale M Jr Malik HS Convergent evolution of escape from hepaciviral antagonism in primates PLoS Biol 2012 10 3 e1001282 PMCID 3302847 Horner SM Park HS Gale M Jr Control of innate immune signaling and membrane targeting by the Hepatitis C virus NS3 4A protease are governed by the NS3 helix alpha0 J Virol 2012 86 6 3112 20 PMCID 3302330 Horner SM Liu HM Park HS Briley J Gale M Jr Mitochondrial associated endoplasmic reticulum membranes MAM form innate immune synapses and are targeted by hepatitis C virus Proc Natl Acad Sci U S A 2011 Horner SM Gale M Jr Intracellular innate immune cascades and interferon defenses that control hepatitis C virus J Interferon Cytokine Res 2009 29 9 489 98 DiMaio D Johung K Goodwin EC

    Original URL path: http://mgm.duke.edu/faculty/horner/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Faculty and Research Maria Cardenas Corona PhD Research Professor research lab members publications lab website Lab members Maria Cardenas Corona Research Professor Joanne Kingsbury Post Doctoral Fellow

    Original URL path: http://mgm.duke.edu/faculty/cardenas/lab.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    regulatory subunits provide Sit4 dependent and rapamycin sensitive sap function in Saccharomyces cerevisiae PLoS One 4 e6331 Bastidas R J Heitman J and Cardenas M E 2009 The protein kinase Tor1 regulates adhesin gene expression in Candida albicans PLoS Pathogens 5 e1000294 Puria R and Cardenas M E 2008 Rapamycin bypasses vesicle mediated signaling events to activate Gln3 in Saccharomyces cerevisiae Communicative Integrative Biology 1 23 25 Bastidas R J Reedy J L Morales Johansson H Heitman J and Cardenas M E 2008 Signaling cascades as drug targets in model and pathogenic fungi Current Opinion in Investigational Drugs 9 856 864 Puria R Zurita Martinez S A and Cardenas M E 2008 Nuclear translocation of Gln3 in response to nutrient signals requires Golgi to endosome trafficking in Saccharomyces cerevisiae Proc Natl Acad Sci USA 105 7194 7199 This study was featured on the cover and highlighted by a commentary in the same PNAS issue It was also highlighted in the editor s choice section of Science Signaling A M VanHook Route to Specificity Sci Signal 1 ec199 2008 Rohde J R Bastidas R Puria R and Cardenas M E 2008 Nutritional control via Tor signaling in Saccharomyces cerevisiae Current Opinion in Microbiology 2 153 160 Rutherford J C Chua G Hughes T Cardenas M E and Heitman J 2008 A Mep2 dependent transcriptional profile links permease function to gene expression during pseudohyphal growth in Saccharomyces cerevisiae Molecular Biology of the Cell 19 3028 3039 Zurita Martinez S A Puria R Pan X Boeke J D and Cardenas M E 2007 Efficient Tor signaling requires a functional Class C Vps protein complex in Saccharomyces cerevisiae Genetics 107 2139 2150 Bahn Y S Xue C Idurm A Rutherford J C Heitman J and Cardenas M E 2007 Sensing the environment Lessons from

    Original URL path: http://mgm.duke.edu/faculty/cardenas/pubs.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    Research Track Faculty Lizzie J Harrell PhD Research Professor bio publications lab website Lab members Harrell Lizzie 684 2707 116 CARL lizzie harrell duke edu

    Original URL path: http://mgm.duke.edu/faculty/harrell/lab.htm (2014-06-13)
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  • Duke University Department of Molecular Genetics & Microbiology
    LK Kong GR Corey GS Gottlieb RS McClelland DJ Sexton D Gesty Palmer LJ Harrell Recurrent Staphylococcus aureus bacteremia Pulsed field gel electrophoresis findings in 29 patients J Infect Dis 1999 179 1157 1161 Murdoch DR Mirrett S Harrell LJ Monahan JS Reller LB Sequential emergence of antibiotic resistance in enterococcal bloodstream isolates over 25 years Antimicrob Agents Chemother 2002 46 3676 3678 Golan Y McDermott LA Jacobus NV Goldstein EJ Finegold S Harrell LJ Hecht DW Jenkins SG Pierson C Venezia R Rihs J Iannini P Gorbach SL Snydman DR Emergence of fluoroquinolone resistance among Bacteroides species J Antimicrob Chemother 2003 52 208 213 Weinstein MP Mirrett S Kannangara S Monahan J Harrell LJ Wilson A Reller LB Multicenter evaluation of the use of penicillin and ampicillin as surrogates for in vitro susceptibility testing of imipenem versus enterococci J Clin Microbiol 2004 42 3747 3751 Cheng AC Murdoch DR Harrell LJ Reller LB Clinical profile and strain relatedness of recurrent enterococcal bacteraemia Scand J Infect Dis 2005 37 642 646 Anderson DJ Engemann JJ Harrell LJ Carmeli Y Reller LB Kaye KS Predictors of mortality in patients with bloodstream infection due to ceftazidime resistant Klebsiella pneumoniae Antimicrob Agents Chemother

    Original URL path: http://mgm.duke.edu/faculty/harrell/pubs.htm (2014-06-13)
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