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  • 1905-COHORT, LSADT, and DOS databases | DuPRI
    the Media Announcements Conferences and Workshops Duke Events Calendar Contact Fulltext search Home Research Research Projects and Groups 1905 COHORT LSADT and DOS databases 1905 COHORT LSADT and DOS databases The 1905 COHORT LSADT and DOS databases on the old and the oldest old are from studies carried out in Denmark by Kaare Christensen DuPRI and James Vaupel DuPRI The 1905 COHORT study a 4 wave study follows all Danes born in 1905 and living in Denmark In the first year 1998 of the study 2 262 participated and in the last year 2005 256 participated Data for the 1905 COHORT database is drawn from assessments and physical tests given to the participants as well as from record linkages to Denmark s national population and health registries The LSADT Longitudinal Study of Aging Danish Twins a 6 wave study and DOS Danish Oldest Old Siblings a study with a follow up longitudinal and family perspective databases are similar to the 1905 COHORT study in that all three have used almost identical medical physical cognitive and psychological assessments and each participant s data records have been linked to Denmark s national registries for more information LSADT involves data for 4 700

    Original URL path: https://dupri.duke.edu/research-project-group/1905-cohort-lsadt-and-dos-databases (2016-02-13)
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  • Cardiovascular Health Study (CHS) | DuPRI
    main objective of the CHS is to identify factors related to the onset and course of these diseases The CHS is specifically designed to determine the importance of conventional CVD risk factors in older adults and to identify new risk factors in this age group especially those that may be protective and modifiable An initial 5 201 study participants 2 962 women and 2 239 men were examined annually from 1989 through 1999 An additional sample of 687 blacks 256 men and 431 women was examined from 1992 to 1999 Extensive physical and laboratory evaluations were performed at baseline to identify the presence and severity of CVD risk factors such as hypertension hypercholesterolemia and glucose intolerance subclinical disease such as carotid artery atherosclerosis left ventricular enlargement and transient ischemia and clinically overt CVD These examinations in the CHS permit evaluation of CVD risk factors in older adults particularly in groups previously under represented in epidemiologic studies such as women and the very old Follow up interviews for events were conducted semiannually Examination components have included physical function ADL IADL Upper Extremity Score grip strength medical history e g vision and hearing problems heart problems in siblings hypertension diabetes neurological history

    Original URL path: https://dupri.duke.edu/research-project-group/cardiovascular-health-study-chs (2016-02-13)
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  • Chinese Longitudinal Healthy Longevity Survey (CLHLS) | DuPRI
    s largest surveys concerning health and aging The CLHLS has interviewed 8 959 11 161 16 057 and 14 923 elderly in 1998 2000 20002 and 2005 respectively Totaling in the four waves 10 879 13 985 16 505 and 9 731 face to face interviews were conducted with centenarians nonagenarians octogenarians and elders aged 65 79 respectively At each wave the longitudinal survivors were re interviewed and the deceased and lost follow up interviewees were replaced by additional participants Data on mortality and health status before dying for the 12 136 elders aged 65 112 who died between the 1998 2000 2002 and 2005 waves were collected in interviews with a close family member of the deceased The CLHLS 2008 wave with an expected sample size of about 21 000 interviewees is now in the field Questions were asked concerning many varied areas such as disability health cognitive ability siblings smoking drinking habits exercise living arrangements children nutrition living arrangements housing and other socioeconomic issues The study s extensive data are used to investigate which determinants out of a large set of social behavioral biological and environmental risk factors are important for healthy longevity CLHLS datasets are available as

    Original URL path: https://dupri.duke.edu/research-project-group/chinese-longitudinal-healthy-longevity-survey-clhls (2016-02-13)
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  • Dunedin Multidisciplinary Health and Development Study | DuPRI
    search Home Research Research Projects and Groups Dunedin Multidisciplinary Health and Development Study Dunedin Multidisciplinary Health and Development Study Dunedin continuously follows 1 037 people born over the course of a year 1972 1973 in Dunedin New Zealand The Dunedin study has information for three generations of respondents gathered on topic areas as diverse as cardiovascular health and risk factors respiratory health oral health sexual and reproductive health mental health

    Original URL path: https://dupri.duke.edu/research-project-group/dunedin-multidisciplinary-health-and-development-study (2016-02-13)
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  • E-Risk | DuPRI
    study that collected individual level data on more than 1000 UK twin pairs at ages 5 in 2000 7 in 2002 and 12 in 2007 to investigate how genetic and environmental factors shape children s disruptive behavior The SCoPiC Network provided the E Risk study with funding for a detailed neighborhood survey to gather information about the social contexts e g victimization collective efficacy social cohesion formal and informal social

    Original URL path: https://dupri.duke.edu/research-project-group/e-risk (2016-02-13)
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  • Framingham Heart Study (FHS) Dataset | DuPRI
    longitudinal population studies 1 The FHS Original Cohort was launched at Exam 1 in 1948 9 1948 4 1953 and has continued with biennial examinations to the present The FHS Original Cohort consists of 5 209 respondents 55 females aged 28 62 years residing in Framingham Massachusetts between 1948 and 1951 Nearly all subjects were Caucasians Examination included an interview physical examination and laboratory tests 2 The Offspring Cohort FHSO This was launched at Exam 1 in 1971 8 1971 9 1975 and has on average been examined every 3 to 4 years since enrollment The FHSO dataset consists of a sample of 3 514 biological descendants of the Original Cohort 1 576 of their spouses and 34 adopted offspring for a total sample of 5 124 subjects 52 females Contact is Duke Research Professor Anatoli I Yashin The FHSO Offspring Cohort subjects were enrolled in 1971 1975 using research protocols similar to those of the FHS so that comparisons of the results from the FHSO and the FHS could be made Beginning in 2002 4 095 adults 53 females having at least one parent in the Offspring Cohort enrolled in the Third Generation Cohort The objective of new recruitment was to complement phenotypic and genotypic information obtained from prior generations with priority assigned to larger families Self reports of ethnicity across all three generations were 99 7 whites reflecting the ethnicity of the population of Framingham in 1948 Phenotypic traits collected in the FHS cohorts over 59 years of follow up relevant to Center research include physiological indices disease risk factors and biomarkers e g blood pressure pulse pressure pulse rate blood glucose cholesterol height weight hematocrit ages at disease onsets behavioral and life history characteristics selected markers of aging and stress resistance e g age at natural menopause

    Original URL path: https://dupri.duke.edu/research-project-group/framingham-heart-study-fhs-dataset (2016-02-13)
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  • Great Smoky Mountains Study | DuPRI
    The Great Smoky Mountains Study GSMS is a longitudinal population based community survey of children and adolescents in North Carolina The study is part of a collaborative effort between Duke University and the North Carolina State Division of Developmental Disabilities Mental Health and Substance Abuse Services It began in 1992 and continued until 2003 Some of the goals of the study were to estimate the number of youth with emotional and behavioral disorders the persistence of those disorders over time the need for and use of services for emotional and behavioral disorders and the possible risk factors for developing emotional and behavioral disorders The participants in GSMS include 1 073 children aged 9 through 16 and their parents from 11 counties in western North Carolina These counties include both urban and rural areas and every agency in the area that provides child mental health services were included in the study This area is also home to a fairly large American Indian population and 349 of the youth in the study are enrolled members of the Eastern Band of the Cherokee Nation These youth represent a population that has been under represented in mental health research across the country The GSMS

    Original URL path: https://dupri.duke.edu/research-project-group/great-smoky-mountains-study (2016-02-13)
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  • Honolulu Heart Study (HHS) | DuPRI
    American men representing a response rate of 72 living in Hawaii identified from a roster of 23 000 men on the 1940 42 selective service registry for Hawaii who were born 1900 1919 Four main examinations were conducted The first examination was in 1965 68 the second in 1967 70 the third in 1971 74 and the fourth in 1991 93 Deaths and morbid events were tracked to 1994 The four exams collected data on anthropometric variables incl height and weight physical measures incl ventricular rate blood pressure vital capacity blood chemistries incl hematocrit serum cholesterol serum triglyceride uric acid and serum glucose and indicators of CHD stroke and diabetes Exams 1 and 4 collected exercise and lifestyle measures incl diet tobacco and alcohol use Exam 4 added additional measures on physical activity activity limitations performance based physical function ADL IADL cognitive function prescription and OTC medications Three additional examinations were conducted during 1970 82 on a 30 sub sample of those completing Exam 2 plus all individuals in the highest decile of serum triglyceride or serum cholesterol in Exam 1 These examinations were conducted in 1970 72 1975 78 and 1980 82 and the content focused on the lipoprotein

    Original URL path: https://dupri.duke.edu/research-project-group/honolulu-heart-study-hhs (2016-02-13)
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