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  • Research | Wendy Kelly Research Group
    biochemical means by which Nature constructs molecular scaffolds that appear within and across families of secondary metabolites Another major endeavor of the Kelly group is to adapt a detailed fundamental understanding of such scaffold building systems to the biosynthetic engineering of designer metabolites This latter effort may also be referred to as Synthetic Biology an emerging field that employs chemical and biological tools to manipulate biological systems in a directed

    Original URL path: http://ww2.chemistry.gatech.edu/kelly/research (2015-06-03)
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  • Publications | Wendy Kelly Research Group
    for a New Family of Bacteriocins J Am Chem Soc 131 4327 4334 DOI 10 1021 ja807890a 9 Kathryn E Roege and Wendy L Kelly 2009 Biosynthetic Origins of the Ionophore Antibiotic Indanomycin Org Lett 11 297 300 DOI 10 1021 ol802422n 8 Wendy L Kelly 2008 Intramolecular Cyclizations of Polyketide Biosynthesis Mining for a Diels Alderase Org Biomol Chem 6 4483 4493 DOI 10 1039 b814552k 7 Wendy L Kelly Michael T Boyne II Ellen Yeh David A Vosburg Danica Galonić Neil L Kelleher Christopher T Walsh 2007 Characterization of the Aminocarboxycyclopropane Forming Enzyme CmaC Biochemistry 46 359 368 DOI 10 1021 bi061930j 6 Wendy L Kelly Nathan J Hillson and Christopher T Walsh 2005 Excision of the Epothilone Synthetase B Cyclization Domain and Demonstration of in Trans Condensation Cyclodehydration Activity Biochemistry 44 13385 13393 DOI 10 1021 bi051124x 5 Wendy L Kelly and Craig A Townsend 2005 Mutational Analysis of nocK and nocL in the Nocardicin A Producer Nocardia uniformis J Bact 187 739 746 DOI 10 1128 JB 187 2 739 746 2005 4 Wendy L Kelly and Craig A Townsend 2004 Mutational Analysis and Characterization of Nocardicin C 9 Epimerase J Biol Chem 279 38220 38227

    Original URL path: http://ww2.chemistry.gatech.edu/kelly/publications (2015-06-03)
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  • Links | Wendy Kelly Research Group
    gov sites entrez otool gatechlib BRENDA http www brenda enzymes org NCBI http www ncbi nlm nih gov ExPASy Proteomics Server http ca expasy org Georgia Institute of Technology http www gatech edu School of Chemistry Biochemistry http www chemistry

    Original URL path: http://ww2.chemistry.gatech.edu/kelly/links (2015-06-03)
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  • Home | Lieberman Group
    of proteins involved in these highly regulated pathways focusing on enzymes that perform hydrolysis reactions in an unexpected chemical environment within lipid membrane or near the surface of membranes In the long term we hope to identify small molecule inhibitors to modulate these activities and prevent diseases associated with aberrant signaling behavior Our methods focus on protein crystallography biochemical and biophysical characterization in silico modeling and drug design Our research

    Original URL path: https://ww2.chemistry.gatech.edu/lieberman/ (2015-06-03)
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  • Dr. Adegboyega (Yomi) K. Oyelere | Oyelere Group
    grant July 2001 to November 2001 Yale University Advisor Professor Scott A Strobel Jane Coffin Childs Postdoctoral Fellow July 1998 to June 2001 Yale University Advisor Professor Scott A Strobel Ph D Organic Chemistry June 1998 Brown University Thesis Advisor Professor John S Oliver Thesis Title Abiotic Models for Ribosomal Polypeptide Biosynthesis B Sc Chemistry Industrial Option 1st Class Honors 1992 University of Ibadan Nigeria Professional Experience Assistant Professor Chemistry and Biochemistry Georgia Institute of Technology Atlanta Aug 2005 present Senior Research Scientist Rib X Pharmaceuticals Inc Jan 2004 Aug 2005 Research Scientist II Rib X Pharmaceuticals Inc Nov 2001 Jan 2004 Postdoctoral Associate and Jane Coffin Childs Postdoctoral Fellow Dept of Molecular Biophysics and Biochemistry Yale University New Haven Connecticut July 1998 Nov 2001 Teaching Assistant Pre doctoral Fellow Dept of Chemistry Brown University Providence Rhode Island Aug 1993 June 1998 Graduate Assistant University of Uyo Nigeria through The National Youth Service Corps Nov 1992 Aug 1993 Awards and Honors Jane Coffin Childs Postdoctoral Fellowship for Medical Research 1998 Sigma Xi Award for Outstanding Graduate Student with Potential for further Contribution to Science Brown University 1998 Admitted as a Graduate Member of The Royal Society of Chemistry 1998 Richardson

    Original URL path: http://ww2.chemistry.gatech.edu/oyelere/PI (2015-06-03)
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  • Group Members | Oyelere Group
    Sodji Bryan Moskowitz Michelle Razumov Subhasish Tapadar Shaghayegh Fathi Idris Raji Previous Members Will Guerrant Josh Canzoneri Vishal Patil Imani Jones Celinah Mwakwari Derek Benicewicz Research Publications Funding Links Home Group Members Dr Oyelere Current Members Previous Members Georgia Institute

    Original URL path: http://ww2.chemistry.gatech.edu/oyelere/GroupMembers (2015-06-03)
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  • Current Group Members | Oyelere Group
    Will Guerrant Josh Canzoneri Vishal Patil Imani Jones Celinah Mwakwari Derek Benicewicz Research Publications Funding Links Home Current Group Members Post Doctoral Researchers Dr Subasish Tapadar PhD Graduate Students Berkley Gryder Arren Washington Quaovi Sodji Bryan Moskowitz Michelle Razumov Idris

    Original URL path: http://ww2.chemistry.gatech.edu/oyelere/CurrentMembers (2015-06-03)
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  • Berkley Gryder | Oyelere Group
    Chemistry 2012 DOI 10 1021 bc300158k these authors contributed equally to this work Gryder B E Sodji Q H Oyelere A K Targeted Cancer Therapy Giving Histone Deacetylase Inhibitors All They Need to Succeed Future Medicinal Chemistry 2012 DOI 10 4155 fmc 12 3 Gryder B E Guerrant W Chen C Oyelere A K Oxathiazole 2 one Derivative of Bortezomib Synthesis Stability and Proteasome Inhibition Activity Med Chem Comm 2011 DOI 10 1039 C1MD00208B Patil V Guerrant W Chen P Gryder B Benicewicz D Khan S Tekwani B Oyelere A Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole linked cap group Bioorganic Medicinal Chemistry 2010 18 415 425 DOI 10 1016 j bmc 2009 10 042 Patents Oyelere A K Gryder B E 2010 Sept Histone Deacetylase HDAC Inhibitors Targeting Prostate Tumors and Methods of Making and Using Thereof Application pending Dreaden E C Oyelere A K Gryder B E El Sayed M A 2011 Aug Endocrine Targeted Nanotechnologies for Breast Prostate Ovarian and other Hormone Associated Cancers Application pending Meetings and Symposia Gryder B E Razumov M J Dillard P Khan S Oyelere A K Targeted Epigenetic Treatment Exploiting the Androgen Receptor to Deliver Histone Deacetylase Inhibitors for Advanced Prostate Cancer Clark Atlanta University Symposium March 2012 Atlanta GA Gryder B E Guerrant W Patil V Razumov M J Tapadar S Oyelere A K Targeted Delivery of Epigenetic Therapy Homing in on Prostate and Lung Cancers Industry Partners Symposium Institute for Bioengineering Biosciences at the Georgia Institute of Technology November 2011 Atlanta GA Gryder B E Razumov M J Oyelere A K Targeted Epigenetic Treatment Exploiting the Androgen Receptor to Deliver Histone Deacetylase Inhibitors for Advanced Prostate Cancer Nature Chemical Biology Symposium Cancer Chemical Biology Oct 2011 Cambridge MA Dreaden E C Gryder B E Austin L

    Original URL path: http://ww2.chemistry.gatech.edu/oyelere/BerkleyGryder (2015-06-03)
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