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  • Executive Committee Meeting | Georgia Tech Chemistry & Biochemistry
    C Williams Paper Museum About Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our activities bridge

    Original URL path: http://ww2.chemistry.gatech.edu/www/event/executive-committee-meeting-9 (2015-06-03)
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  • All Events | Georgia Tech Chemistry & Biochemistry
    Defense Vasser Woolley Distinguished Lecture Event Date Time Location Title Event type Executive Committee meeting June 11 2015 11 00 AM MoSE 2100F Faculty Meeting June 25 2015 11 00 AM MoSE 3201A Executive Committee Meeting July 16 2015 11 00 AM MoSE 2100F Faculty Meeting July 21 2015 11 00 AM MoSE 3201A Executive Committee Meeting August 13 2015 11 00 AM MoSE 2100F Faculty Meeting August 18 2015 11 00 AM MoSE 3201A Prof Joseph Sadighi Georgia Institute of Technology September 03 2015 04 00 PM MoSE G011 TBD Colloquium Prof Valeria Molinero University of Utah September 08 2015 04 00 PM MoSE 3201A TBD Physical Division Seminar Executive Committee Meeting September 10 2015 11 00 AM MoSE 2100F Prof Amy Palmer University of Colorado September 10 2015 04 00 PM MoSE G011 TBD Colloquium Pages 1 2 3 4 5 next last See Events Archive Georgia Tech Resources Offices Departments News Center Campus Calendar Special Events GreenBuzz Institute Communications Visitor Resources Campus Visits Georgia Tech Hotel Conference Center Georgia Tech Global Learning Center Visitor Parking Information Directions to Campus GTvisitor Wireless Network Information Barnes Noble at Georgia Tech Ferst Center for the Arts Robert C Williams Paper Museum About Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our activities bridge traditional boundaries between

    Original URL path: http://ww2.chemistry.gatech.edu/www/events/all (2015-06-03)
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  • Featured Research | Georgia Tech Chemistry & Biochemistry
    are post translationally processed macrocyclic peptide metabolites characterized by extensive backbone and side chain modifications that include a six membered nitrogeneous ring thiazol in e oxazol in e rings and dehydrated amino acid residues Thiostrepton A one of the more structurally complex and well studied thiopeptides contains a second macrocycle bearing a quinaldic acid moiety Antibacterial antimalarial and anticancer properties have been described for thiostrepton A and other thiopeptides although the molecular details for binding the cellular target in each case are not fully elaborated We previously demonstrated that a mutation of the TsrA core peptide Ala4Gly supported the successful production of the corresponding thiostrepton variant To more thoroughly probe the thiostrepton biosynthetic machinery s tolerance toward structural variation at the fourth position of the TsrA core peptide we report here the saturation mutagenesis of this residue using a fosmid dependent biosynthetic engineering method and the isolation of 16 thiostrepton analogues Several types of side chain substitutions at the fourth position of TsrA including those that introduce polar or branched hydrophobic residues are accepted albeit with varied preferences In contrast proline and amino acid residues inherently charged at physiological pH are not well tolerated at the queried site by the thiostrepton biosynthetic system These newly generated thiostrepton analogues were assessed for their antibacterial activities and abilities to inhibit the proteolytic functions of the eukaryotic 20S proteasome We demonstrate that the identity of the fourth amino acid residue in the thiostrepton scaffold is not critical for either ribosome or proteasome inhibition Read More Feifei Zhang Feifei Wendy Kelly ACS Chemical Biology 2015 Vol 10 4 pp 998 1009 Visible to UVC upconversion efficiency and mechanisms of Lu 7 O 6 F 9 Pr 3 and Y 2 SiO 5 Pr 3 ceramics Materials that efficiently convert visible light to UVC via upconversion are of interest for their potential as light activated antimicrobial surfaces and in solar water treatment The preparation and photophysical properties of Lu7O6F9 Pr3 were explored and compared to those of Y2SiO5 Pr3 as part of an ongoing effort to find higher efficiency upconversion phosphors Read More Ezra L Cates Angus P Wilkinson Jae Hong Kim Journal of Luminescence 2015 Vol 160 pp 202 209 A Universal Chemical Enrichment Method for Mapping the Yeast N glycoproteome by Mass Spectrometry MS Glycosylation is one of the most common and important protein modifications in biological systems Many glycoproteins naturally occur at low abundances which makes comprehensive analysis extremely difficult Additionally glycans are highly heterogeneous which further complicates analysis in complex samples Lectin enrichment has been commonly used but each lectin is inherently specific to one or several carbohydrates and thus no single or collection of lectin s can bind to all glycans Here we have employed a boronic acid based chemical method to universally enrich glycopeptides The reaction between boronic acids and sugars has been extensively investigated and it is well known that the interaction between boronic acid and diols is one of the strongest reversible covalent bond interactions in an aqueous environment This strong covalent interaction provides a great opportunity to catch glycopeptides and glycoproteins by boronic acid whereas the reversible property allows their release without side effects More importantly the boronic acid diol recognition is universal which provides great capability and potential for comprehensively mapping glycosylation sites in complex biological samples By combining boronic acid enrichment with PNGase F treatment in heavy oxygen water and MS we have identified 816 N glycosylation sites in 332 yeast proteins among which 675 sites were well localized with greater than 99 confidence The results demonstrated that the boronic acid based chemical method can effectively enrich glycopeptides for comprehensive analysis of protein glycosylation A general trend seen within the large data set was that there were fewer glycosylation sites toward the C termini of proteins Of the 332 glycoproteins identified in yeast 194 were membrane proteins Many proteins get glycosylated in the high mannose N glycan biosynthetic and GPI anchor biosynthetic pathways Compared with lectin enrichment the current method is more cost efficient generic and effective This method can be extensively applied to different complex samples for the comprehensive analysis of protein glycosylation Read More Weixuan Chen Johanna M Smeekens Ronghu Wu Molecular Cellular Proteomics 2014 Vol 13 6 pp 1563 1572 Systematic Investigation of Cellular Response and Pleiotropic Effects in Atorvastatin Treated Liver Cells by MS Based Proteomics For decades statins have been widely used to lower cholesterol levels by inhibiting the enzyme HMG Co A reductase HMGCR It is well known that statins have pleiotropic effects including improving endothelial function and inhibiting vascular inflammation and oxidation However the cellular responses to statins and corresponding pleiotropic effects are largely unknown at the proteome level Emerging mass spectrometry based proteomics provides a unique opportunity to systemically investigate protein and phosphoprotein abundance changes as a result of statin treatment Many lipid related protein abundances were increased in HepG2 cells treated by atorvastatin including HMGCR FDFT SQLE and LDLR while the abundances of proteins involved in cellular response to stress and apoptosis were decreased Comprehensive analysis of protein phosphorylation demonstrated that several basic motifs were enriched among down regulated phosphorylation sites which indicates that kinases with preference for these motifs such as protein kinase A and protein kinase C have attenuated activities Phosphopeptides on a group of G protein modulators were up regulated which strongly suggests that cell signal rewiring was a result of the effect of protein lipidation by the statin This work provides a global view of liver cell responses to atorvastatin at the proteome and phosphoproteome levels which provides insight into the pleiotropic effects of statins Read More Haopeng Xiao Weixuan Chen George X Tang Johanna M Smeekens Ronghu Wu Journal of Proteome Research 2015 Vol 14 3 pp 1600 1611 Taming Chlorine Azide Access to 1 2 Azidochlorides from Alkenes We describe a convenient procedure for the safe generation and application of a very useful reagent for the functionalization of alkenes but one that has been heretofore ignored because of safety

    Original URL path: http://ww2.chemistry.gatech.edu/www/featured-research (2015-06-03)
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  • About Description | Georgia Tech Chemistry & Biochemistry
    Williams Paper Museum About Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our activities bridge traditional

    Original URL path: http://ww2.chemistry.gatech.edu/www/about-description (2015-06-03)
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  • Academics Description | Georgia Tech Chemistry & Biochemistry
    Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our activities bridge traditional boundaries between scientific disciplines and involve

    Original URL path: http://ww2.chemistry.gatech.edu/www/academics-description (2015-06-03)
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  • Research - Quote | Georgia Tech Chemistry & Biochemistry
    Georgia Tech Hotel Conference Center Georgia Tech Global Learning Center Visitor Parking Information Directions to Campus GTvisitor Wireless Network Information Barnes Noble at Georgia Tech Ferst Center for the Arts Robert C Williams Paper Museum About Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer

    Original URL path: http://ww2.chemistry.gatech.edu/www/research-quote (2015-06-03)
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  • Research - About | Georgia Tech Chemistry & Biochemistry
    Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our activities bridge traditional boundaries between scientific disciplines and involve

    Original URL path: http://ww2.chemistry.gatech.edu/www/research-about (2015-06-03)
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  • Safety Description | Georgia Tech Chemistry & Biochemistry
    Arts Robert C Williams Paper Museum About Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures Research Areas Summer Research Opportunities Undergraduate Research Centers Facilities Services Conferences Academics Graduate Programs Apply Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Student Life Undergraduate Programs Apply B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Careers Courses Advising Employment Opportunities Undergraduate Research Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life Safety Important Contact Info Emergencies Safety Training Safety Procedures Material Safety Data Sheet Resources Forms Hazardous Gases Program Safety Links People Faculty Staff Directory Advisory Board Faculty Awards Graduate Awards Undergraduate Awards Employment Opportunities Alumni Friends Advisory Board Alumni News Events Giving School of Chemistry Biochemistry 901 Atlantic Drive Atlanta GA 30332 0400 404 894 4002 phone 404 894 7452 fax Home Centers Facilities Directory Advisory Board Log In Emergency Information Legal Privacy Information Accessibility Accountability Accreditation Employment 2015 Georgia Institute of Technology About the School of Chemistry Biochemistry Core Values Mission Programs Facilities Services Employment Opportunities History Community Organizations Finding Us News Archive Events Archive Policies Procedures The home of our school the Molecular Science and Engineering building Our Undergraduate Graduate Programs Graduate Programs Undergraduate Programs Graduate Apply to Our Graduate Programs Degree Programs Degree Requirements Assistantships Fellowships Employment Opportunities Courses Graduate Awards Graduate Student Life Undergraduate Apply to Our Undergraduate Programs B S Chemistry Program B S Biochemistry Program Freshman Chemistry Program Minors Courses Careers Advising Undergraduate Research Undergraduate Research Projects Undergraduate Internship Travel Scholarships Course Permits Undergraduate Student Life UG Blog Research Opportunities Areas Areas Summer Research Opportunities Undergraduate Research Undergraduate Research Projects Centers Facilities Services Conferences The school is engaged in cutting edge research across the full breadth or modern chemistry and biochemistry Our

    Original URL path: http://ww2.chemistry.gatech.edu/www/safety-description (2015-06-03)
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