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  • Downstream Processing Course
    whole process Attendees include Engineers and scientists interested in design economics validation optimization and scale up of biochemical product recovery Protein biochemists and chemists involved in design of recovery processes Managers responsible for biochemical process development Entrepreneurs attorneys and business leaders seeking an overview and insight into biochemical manufacturing Back to Top Course Format The course faculty have worked together for over 25 years teaching this course The format includes a series of lectures on individual topics and discussion of case studies All students participate in a group design exercise to bring together systems thinking about process synthesis and design The lectures begin promptly at 9 00 am Monday Lectures end at 5 30 pm each day except Friday when they finish by 12 00 noon In addition to classroom lectures attendees will participate on team projects with break out teams from 1 00 2 00 pm Monday through Thursday Team project presentations are made on Friday from 9 00 am to noon Tuition includes both electronic USB flash drive and hard copy versions of the lecture notes These are made available to participants during the week of class Back to Top Outline of the Course The course begins with an introduction to the recovery problems created by fermentation cell culture and enzyme technology Subsequent topics include Process design The first steps Biochemical Processing Overview Virus clearance in downstream process of cell culture based therapeutics Centrifugation Chromatography Quality Beyond pass or fail Filtration fundamentals Extraction case study MAB case study Process design economics Process validation Quality by Design Filtration application Team design project There are discussions of case studies to illustrate innovations in downstream processing The class is divided into teams early in the week to work as a team on a project that illustrates the concepts from the lectures Back to Top Course schedule registration times special events View 2016 Course Schedule pdf subject to change Class runs 9 00 am 5 30 pm every day except Friday when it ends at 12 00 noon Special events include a reception for course participants and faculty on Monday night and a dinner on Thursday evening All evening activities are included in tuition Back to Top Participants Comments Product Lead GlaxoSmithKline Good grounding in downstream processing which I will be able to apply to my day to day job Shift Manager Recovery Manufacturing at Genentech I really enjoyed the course and felt that it strengthened my understanding of downstream processes and the considerations you have to make when designing a process Development Engineer II Millipore Corporation Excellent intellectually promising and very informative Technical Service Representative Eli Lilly and Company Course provides a comprehensive review of the key aspects of downstream processing from both a technical and economical perspective Instructors are industry and academic leaders in biotech and provide insight into new technologies for existing application and new applications for existing technology senior scientist amgen manufacturing ltd Great balance between basics advanced topics and academic real world applications analytical chemist sweetwater energy

    Original URL path: http://web.mit.edu/professional/short-programs/courses/downstream_processing.html (2016-02-01)
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  • ChemE | News | Hottel Lecture
    future generations of students The inaugural Hottel Lecture was presented in April 1985 by Professor Hottel himself The Hottel Legacy Professor Hottel began his career at MIT in 1924 He served as faculty member from 1928 to 1968 He was Professor of Fuel Engineering 1941 1965 Director Fuels Research Laboratory 1938 1968 Chairman Solar Energy Research Committee 1938 1964 Carbon P Dubbs Professor of Chemical Engineering 1965 1968 He remained an active member of the Department as Professor Emeritus from 1968 until his death in 1998 Professor Hottel s record of long standing interest and achievement was in the area of more effective use of energy His work spanned over fifty years and focused on better utilization of fossil fuels with occasional intensive digressions into solar energy It embraced major contributions to the maturation of industrial furnace and boiler design from an art to a science to solar heating and to early identification and study of other energy related problems His awards include the United States Medal for Merit King s Medal Great Britain William H Walker Award AIChE Edgerton Gold Medal Combustion Institute Melchett Medal Institute of Fuel Great Britain Max Jakob Award AIChE and ASME Founders Award AIChE Farrington Daniels Award Royal Society London Founders Award NAE and the John Fritz Medal United Engineering Trustees He was a member of the National Academy of Sciences the National Academy of Engineering and the American Academy of Arts and Sciences Previous Lectures 2014 Professor Arun Majumdar Stanford University 2013 Professor Emily Carter Princeton University 2012 Dr Eric Toone Principal Deputy Director ARPA E US Dept of Energy 2012 Nathan S Lewis Caltech Beckman Institute and Kavli Nanoscience Institute 2010 Steven E Koonin Under Secretary for Science US Dept of Energy 2009 William J Koros Georgia Institute of Technology 2008 Vinod

    Original URL path: http://web.mit.edu/cheme/news/hottel/hottel_lecture_prev.html (2016-02-01)
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  • ChemE | Webcast Archives
    Biology University of Texas Austin Friday May 3 2013 Lecture Video The Warren K Lewis Lectureship in Chemical Engineering Dr Yoshimitsu Kobayashi President and Chief Executive Officer Mitsubishi Chemical Holdings Corporation Friday April 5 2013 Lecture Video Hoyt C Hottel Lecture in Chemical Engineering Dr Eric Toone Principal Deputy Director Advanced Research Projects Agency Energy ARPA E US Department of Energy Friday November 30 2102 Lecture Video Adel F Sarofim Memorial Symposium May 11 2012 MIT Chemical Engineering Department Lecture Videos 12 The Warren K Lewis Lectureship in Chemical Engineering George M Whitesides Department of Chemistry Chemical Biology Harvard University Friday May 4 2012 Lecture Video Alan S Michaels Distinguished Lectureship John Maraganore CEO Alnylam Pharmaceuticals Friday April 27 2012 Lecture Video Hoyt C Hottel Lecture in Chemical Engineering Nathan S Lewis Caltech Beckman Institute and Kavli Nanoscience Institute Friday April 13 2012 Lecture Video The Daniel I C Wang Lecture on the Frontiers of Biotechnology Chris Somerville Energy Biosciences Institute University of California Berkeley Friday October 14 2011 Lecture Video Alan S Michaels Distinguished Lectureship Cato T Laurencin 87 Chemical Engineering Dean of School of Medicine University of Connecticut Friday May 6 2011 Lecture Video The Warren K Lewis Lectureship in Chemical Engineering Gary S Calabrese Senior Vice President and Director Photovoltaic Glass Technologies Corning Inc April 29 2011 Lecture Video The Daniel I C Wang Lecture on the Frontiers of Biotechnology Professor Tillman Gerngross Dartmouth College April 15 2011 Lecture Video Hoyt C Hottel Lecture in Chemical Engineering Steven E Koonin Under Secretary for Science US Dept of Energy September 22 2010 Lecture Video Symposium to Honor Professor Emeritus Edward W Merrill 47 A celebration of 60 years as a member of the MIT faculty May 14 2010 Lecture Video The Warren K Lewis Lectureship in Chemical Engineering Chaitan Khosla Professor Departments of Chemistry Chemical Engineering and by courtesy Biochemistry Stanford University April 30 2010 Lecture Video Alan S Michaels Distinguished Lectureship Robert L Bratzler Executive Chairman Selecta Biosciences Friday April 2 2010 Lecture Video The Warren K Lewis Lectureship in Chemical Engineering William F Banholzer Executive Vice President and Chief Technology Officer Dow Chemical Company April 17 2009 Webcast Windows Media Player version 9 or later is needed Free Download Alan S Michaels Distinguished Lectureship Nicholas A Peppas Fletcher S Pratt Chair of Chemical Engineering Biomedical Engineering and Pharmaceutics University of Texas at Austin April 3 2009 Webcast Windows Media Player version 9 or later is needed Free Download The Daniel I C Wang Lecture on the Frontiers of Biotechnology Professor Peter Schultz Scripps Professor of Chemistry Scripps Research Institute Director of the Genomics Institute of the Novartis Research Foundation March 20 2009 Webast Windows Media Player version 9 or later is needed Free Download Hoyt C Hottel Lecture in Chemical Engineering Vinod Khosla Founder Khosla Ventures September 23 2008 Webcast Warren K Lewis Lectureship John F Brady Professor of Chemical Engineering California Institute of Technology May 9 2008 Webcast Broadband 220K Dial up 56K Alan S

    Original URL path: http://web.mit.edu/cheme/news/webcast.html (2016-02-01)
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  • ChemE | News | Wang Lecture
    Wang Lecture Student Seminar News Archives Inaugural Daniel I C Wang Lecture on the Frontiers of Biotechnology Expanding the enzyme universe by evolution and design Frances H Arnold Dick and Barbara Dickinson Professor Division of Chemistry Chemical Engineering California Institute of Technology Friday September 26 2014 3 00 p m Room 32 123 Massachusetts Institute of Technology Dr Frances H Arnold is the Dick and Barbara Dickinson Professor of Chemical Engineering Bioengineering and Biochemistry and Director of the Rosen Bioengineering Center at the California Institute of Technology Her research focuses on directed evolution and protein engineering with applications in alternative energy chemicals and medicine Dr Arnold received her bachelor s degree in mechanical and aerospace engineering from Princeton University in 1979 and her PhD in chemical engineering at the University of California Berkeley in 1985 After postdoctoral work in biophysical chemistry at UC Berkeley she joined the Caltech faculty in chemical engineering in 1987 At Caltech Dr Arnold pioneered the directed evolution of proteins mimicking Darwinian evolution in the laboratory to create new biological molecules Her laboratory has developed methods of laboratory evolution and structure guided recombination that are used widely in industry and basic science to engineer proteins with new and interesting properties Dr Arnold is the recipient of numerous honors including induction into the National Inventors Hall of Fame 2014 the Eni Prize in Renewable and Nonconventional Energy 2013 the National Medal of Technology and Innovation 2011 and the Charles Stark Draper Prize of the US National Academy of Engineering 2011 She has been elected to membership in all three US National Academies of Science Medicine and Engineering Dr Arnold serves as a judge for the Queen Elizabeth Prize in Engineering and on the President s International Advisory Council of the King Abdullah University of Science and Technology

    Original URL path: http://web.mit.edu/cheme/news/wang/wang_2014.html (2016-02-01)
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  • ChemE | In the News | Commencement
    Science William G Baysinger Jacqueline A Brew Javier E Casas KamYu Cheng Carlos Domene Sergio Fernandez Nadiah Jenkins Ernesto Jimenez Marc R Kaloustian Nikita A Khlystov Charlotte S Kirk Zainab A Lasisi Chang Ho Lee Brandon M Lowe Nyasha Madziva Patricia C Mayer Douglas E Nmagu Ivana Polim Mariana Rodriguez Michaelann Rodriguez Anthony E Saad Jacqueline P Simpson Pritee S Tembhekar Maria Z Tou Shirley Tsang Curtis L Wu Katherine A Wymbs Brian S Alejandro Rohan Kabir D Amin Emma F Broderick Justin L Bullock Megan E Bumgarner Victor J Cantu Kevin A Clayton Flor L De La Cruz Samantha R Hagerman Jennifer Y Hsu David Huang Veronica M Hume Vinati Kaul Samuel Lim Ruby C Maa Cameron S McAlpine Crystal McKenzie Monica E Neugebauer Joshua I Santos Heard Michelle H Teplensky Joshua A Zeidman Yining Zhang Rose G Feldman Paige E Finkelstein Tejas A Navaratna Benjamin C Niswonger Eric R Safai Ezequiel Schmois Xuefei Bai Stephanie Birkhimer Maria R Chan Ryan A Friedrich Akshar Wunnava Rebecca Han Ian S Osborn Kevin L Wu Devin D Zhang PhD David C Borrelli Himanshu Hemant Dhamankar Yin Fan Todd Richard Ferguson Jonathan Brian Gilbert Yuan Gong Patrick Louis Heider Andrew Joseph Hilmer Amrit Jalan Yuko Kida Seok Joon Kwon Hyomin Lee Zan Liu David Shin Ren Liu Xianwen Mao Joshua Eugene Middaugh Vanessa Marie Peterson Christy Danielle Petruczok Eric M Pridgen Katie Julia Quinn Vinay Raman Nigel Forest Reuel Kittipong Saetia Spencer Daniel Schaber Nisarg Jaydeep Shah Micah James Sheppard Chih Jen Shih Eric Chun Jen Shiue Michael Craig Stern Carla Thomas Achim Wechsung Rong Yang Xiaochuan Yang SM Master of Science Matthew P Dumouchel ScD Doctor of Science Kevin Yu Ming Lin Maria Jose Nieves Remacha MSCEP Master of Science in Chemical Engineering Practice Harry An Alexander Jules Bourque Zachary Buras

    Original URL path: http://web.mit.edu/cheme/news/2014/graduates.html (2016-02-01)
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  • ChemE | In the News | Kristala Prather Granted Tenure
    an important part of our Department s future Prather is an investigator in the multi institutional Synthetic Biology Engineering Research Center SynBERC funded by the National Science Foundation USA She received an SB degree from MIT in 1994 and PhD from the University of California Berkeley 1999 and worked four years in BioProcess Research and Development at the Merck Research Labs Rahway N J She is the recipient of a Camille and Henry Dreyfus Foundation New Faculty Award 2004 an Office of Naval Research Young Investigator Award 2005 a Technology Review TR35 Young Innovator Award 2007 a National Science Foundation CAREER Award 2010 and the Biochemical Engineering Journal Young Investigator Award 2011 Additional honors include selection as the Van Ness Lecturer at Rensselaer Polytechnic Institute 2012 and a Young Scientist of the World Economic Forum Annual Meeting of the New Champions 2012 Prather has been recognized for excellence in teaching with the C Michael Mohr Outstanding Faculty Award for Undergraduate Teaching in the Dept of Chemical Engineering 2006 and the MIT School of Engineering Junior Bose Award for Excellence in Teaching 2010 Prather is an important asset to organizations across the campus For example she has been a long time collaborator of the MIT Portugal Program MPP an international collaboration between MIT the Portuguese government and industry Prather is a faculty member of the MPP s Bioengineering focus area and under this program she participates in research projects in collaboration with Portuguese Faculty at Instituto Superior Técnico Lisboa Portugal in the development and test of E coli strains specifically adapted to meet the upstream and downstream processing challenges associated with large scale production of plasmid vectors She is also a supervisor of several PhD Bioengineering MPP PhD candidates that have been developing part of their research project at her MIT

    Original URL path: http://web.mit.edu/cheme/news/2013/prather.html (2016-02-01)
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  • ChemE | In the News | Assistant Professor Fikile R. Brushett
    Student Seminar News Archives In the News MIT ChemE welcomes new assistant professor Fikile R Brushett On December 3 2012 MIT Chemical Engineering welcomed its latest faculty member Assistant Professor Fikile R Brushett As of January 1 2013 Prof Brushett holds the Raymond A Helen E St Laurent Career Development Chair He received his bachelor s degree in Chemical Biomolecular Engineering from the University of Pennsylvania in 2006 In 2010 he completed his Ph D in Chemical Engineering at the University of Illinois at Urbana Champaign under the supervision of Professor Paul J A Kenis His research at UIUC focused on microfluidic fuel cells At Illinois Brushett was the recipient of a GEM Fellowship a SURGE Fellowship and a Harry G Drickamer Research Fellowship From 2010 to 2012 Brushett was a Director s Postdoctoral Fellow at Argonne National Laboratory ANL working with Dr Jack Vaughey At ANL his research focused on non aqueous redox flow batteries and developing in situ imaging techniques for lithium ion batteries A key societal challenge in 21st century will be the distribution of energy in an efficient cost effective and sustainable fashion Professor Brushett s research group focuses on the design synthesis and characterization of

    Original URL path: http://web.mit.edu/cheme/news/2013/Brushett.html (2016-02-01)
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  • ChemE | In the News | 2012 Department of Chemical Engineering Award
    Lecture Lewis Lecture Michaels Lecture Wang Lecture Student Seminar News Archives In the News 2012 Department of Chemical Engineering Award and Fellowship Winners Merck Technology Fellowship Award Jared Forman 13 Merck Manufacturing Diversity Fellowship Award Tejas Navaratna 14 Robert T Haslam Cup Awarded to a student who shows outstanding professional promise in Chemical Engineering Mengfei Yang 12 Roger de Friez Hunneman Prize Recognizes outstanding scholarship in class and research Shawn Pan 12 Gates Cambridge Scholarship Joshua Cohen 12 Allison Hinckley 12 Phi Beta Kappa Yunxin Joy Jiao 12 Genentech Scholar Award Michelle Dion 13 Amgen Scholar Nikita Consul 13 MIT Federal Credit Union People Helping People Award Corinne Carland 13 Wing S Fong Memorial Prize Awarded to a chemical engineering senior of Chinese descent with the highest cumulative GPA in honor of the memory of Wing S Fong his hard work and dedication to his adopted home university and country Yuewei Lucy Ji 12 Yunxin Joy Jiao 12 C Michael Mohr Outstanding Faculty Award Recognizes excellence in teaching in undergraduate subjects Narendra Maheshri Assistant Professor of Chemical Engineering Edward W Merrill Outstanding Teaching Assistant Award Cary Opel G Outstanding Graduate Teaching Assistant Award Karthik Shekhar G Graduate Student Council Outstanding Faculty Award Arup Chakraborty Robert T Haslam Professor of Chemical Engineering William Deen Carbon P Dubbs Professor Fall 2011 Best Student Seminar Karthik Shekhar G Spring 2012 Best Student Seminar Mitchell Wang G Chemical Engineering Outstanding Employee Award Gwen Wilcox Administrative Assistant Chemical Engineering Individual Accomplishment Award Gracie Dorneus Administrative Assistant Rachel Howden G Chemical Engineering Dept Special Service Awards Mary Boyd 12 Irene Brockman G Timothy Chang 12 Noemie Manuelle Dorval Courchesne G Paige Finkelstein 14 Connie Gao G Allison Hinckley 12 Saloni Jain 12 Mark Kalinich 13 Lauren Kazmierski 12 Charlotte Kirk 14 Justin Kleingartner G Molly Kozminsky

    Original URL path: http://web.mit.edu/cheme/news/2012/cheme-award.html (2016-02-01)
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