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    and Matthew J Carpenter specifically tests the translation of adult treatments to adolescent smokers Dr Carpenter was recruited to the HCC after completing a post doctoral fellowship and both Drs Gray and Carpenter have received pilot funding to produce the initial data on smoking in teens which has led to multiple NIH funded studies These researchers successfully conducted the first randomized controlled trial that compared the combined versus separate effects of sustained release bupropion and contingency management demonstrating superiority of combined pharmacologic and behavioral intervention They also were among the first to test what is likely the most efficacious treatment for adult smokers varenicline in the adolescent population This latter work led to the largest test trial of varenicline for adolescent smoking cessation funded by the NIH Drs Carpenter Gray and Anthony J Alberg have also conducted the first randomized clinical trial to evaluate the effects of practice quit attempts PQA alone vs PQA plus nicotine replacement therapy NRT sampling PQA NRT in smokers who are not motivated to quit Overall NRT sampling was associated with a significantly higher incidence of smokers making quit attempts and higher rates of abstinence Uptake of evidence based treatment was higher among those receiving

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/research/programs/cancer_control/featured_project.htm&VersionObject=C593016A514D1B365B160FFCDC7B83AC&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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    radical generation gene expression detection of collagen fibers and other factors in living animals and tissues The Confocal Multiphoton Microscopy Unit is equipped with the following instruments Zeiss LSM 510 NLO META multi photon laser scanning confocal multiphoton microscope Multiple lasers for excitation at 458 477 488 514 543 and 633 nm and multi tracking permit simultaneous recording of multicolor fluorescence in the confocal mode A recently upgraded Coherent Chameleon Ultra II Verdi laser provides multiphoton excitation tunable from 680 nm to 1080 nm A META photomultiplier array detector provides spectral detection and unmixing for both 1 photon and multiphoton fluorescence An environmental chamber controls stage and objective temperature and specimen atmosphere Note an NIH instrumentation application is pending that would support the upgrade of this instrument to a Zeiss LSM 780 34 Channel Quasar Zeiss LSM 510 META Except for multiphoton capability this microscope has all the capabilities of the LSM 510 NLO META microscope described above Olympus FluoView FV10i LIV The Fluoview FV10i is a self contained compact inverted confocal laser scanning microscope with water immersion optics and environmental control for live cell imaging Four diode lasers provide excitation at 405 473 559 and 635 nm Detection uses a variable bandpass filter allowing selection of the most suitable wavelength for a particular fluorophore Olympus FV1200 MPE The FV1200 MPE is a dedicated multiphoton microscope configured for intravital imaging of live animals and is scheduled for installation in the near future This inverted microscope is equipped with long working distance water and silicone oil immersion objectives tunable multiphoton laser with prechriping and highly efficient GaAsP detectors for intravital multiphoton projects in the future and will uniquely evaluate tumor metabolism and cell biology in vivo in response to genetic manipulations pharmacologic agents and cancer chemotherapy drugs Leica TCS SP2 AOBS

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/research/resources/cellandmolecularimaging/confocalmultiphoton.htm&VersionObject=1EA75CEB83F174D4E84D032801EA51E2&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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    Chadrick E Denlinger MD Associate Professor Department of Surgery Lung Nodule Risk Stratification with Broncholveolar Lavage Fluid Analysis Graham W Warren MD PhD Associate Professor Department of Radiation Oncology A Novel Model of Therapeutic Response in Cancer Cells Yi Yang

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/research/funding/PilotAwardees.htm&VersionObject=7DEF9D6BA41A3517C474076B88B8E961&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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  • 2014 Best Recipe Contest Winners
    with electric mixer until blended 3 Mix in sour cream and vanilla flavor Let stand for 5 minutes 4 Arrange layer of wafers in a serving bowl or individual serving glass containers such as tall narrow or short stemmed glasses 5 Add a layer of banana slices top with 1 3 of the pudding mixture Repeat layers ending with pudding Top with cool whip Note If using individual serving containers layer ingredients accordingly 6 Refrigerate until ready to serve 2nd Place Sloppy Joes Ethel Simmons representing Church House of Ministries Ingredients 1 pound of lean ground beef 1 4 cup chopped onion 1 4 cup chopped green pepper 1 2 cup of crushed tomatoes 1 cup of carrots 1 teaspoon of yellow mustard 3 4 cup ketchup 1 4 cup of Honey BBQ sauce 1 teaspoon garlic powder 1 teaspoon chili powder Salt and pepper to taste 2 packets of splenda Preparation 1 Heat skillet over medium heat cook and stir beef Add onions green peppers carrots crushed tomatoes garlic powder chili powder and splenda 2 Stir in BBQ sauce ketchup and mustard mix thoroughly Reduce heat to low and simmer until sauce thickens about 30 minutes Season with salt and pepper 3rd Place Lip Smakin Mac n Cheese Serves 4 Garcia Williams representing the Charleston Alumnae Chapter of Delta Sigma Theta Sorority Ingredients Salt to taste 4 ounces whole wheat macaroni 1 2 cup onion garlic puree 1 2 teaspoon dry mustard Pinch cayenne pepper 1 cup shredded reduced fat cheddar 50 percent 1 3 cup nonfat Greek Yogurt 1 4 cup whole wheat panko bread crumbs 1 4 cup grated Parmesan Cheese Preparation 1 Preheat the oven to 425 degrees Spray an 8 by 8 inch baking dish with cooking spray 2 Bring a large pot of salted

    Original URL path: http://hcc.musc.edu/commitments/partnerships/Community%20Compass%20Project/2014%20Compass%20Project/bestrecipe2014.htm (2015-11-11)
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    Partial Breast Irradiation PBI for Women with Stage 0 I or II Breast Cancer CTO 101527 ECOG 5508 Lung Program Active Closed to Accrual A Randomized Phase III Study of Maintenance Therapy with Bevacizumab Pemetrexed or a Combination of Bevacizumab and Pemetrexed Following Carboplatin Paclitaxel and Bevacizumab for Advanced Non Squamous NSCLC CTO 101453 SWOG S0702 Active Closed to Accrual A Prospective Observational Multicenter Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw ONJ in Cancer Patients with Bone Metastases Starting Zoledronic Acid Treatment CTO 101904 CALGB 80702 Active enrolling A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX Plus Celcoxib or Placebo for Patients with Resected Stage III Colon Cancer CTO 101628 SWOG S1007 Active enrolling A Phase III Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy Chemotherapy in Patients witn 1 3 Positive Nodes Hormone Receptor Positive and HER2 Negative Breast Cancer with Recurrence Score RS of 25 or Less RxPONDER A Clinical Trial Rx for Positive Node Endocrine Responsive Breast Cancer CTO 102078 SWOG S1400 Active enrolling Phase II III Biomarker Driven Master Protocol for Second Line Therapy of Squamous Cell Lung Cancer Lung Master Protocol CTO 102180 NSABP B52 Active enrolling

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/commitments/clinicaltrialsnetwork/members/georgetown.htm&VersionObject=DF939D83B80B1F2BFBF130D66B223304&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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    closed to accrual A Randomized Phase III Trial Comparing 16 to 18 weeks of Neoadjuvant Exemestane 25 mg daily Letrozole 2 5 mg or Anastrozole 1 mg in Postmenopausal Women with Clinical Stage II and III Estrogen Receptor Positive Breast Cancer CTO 101374 ACOSOG Z1071 closed to accrual A Phase II Study Evaluating the Role of Sentinel Lymph Node Surgery and Axillary Lymph Node Dissection Following Preoperative Chemotherapy in Women

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/commitments/clinicaltrialsnetwork/members/hiltonhead.htm&VersionObject=AAA0E1C207D8D305B7955A3D58D40C69&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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    Visit the McLeod Health website Get directions to McLeod Health Participation in the following CTN Investigator Initiated studies CTO 101678 Gastrointestinal Closed A Phase II III Multi center Randomized Controlled Study to Compare the Efficacy and Safety of Gemcitabine Alone

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/commitments/clinicaltrialsnetwork/members/mcleod.htm&VersionObject=346A7FAA583B719D525190CEE8225762&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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    Positive Ductal Carcinoma In Situ Resected by Lumpectomy CTO 101867 SWOG S1207 Active Enrolling Phase III Randomized Placebo Controlled Clinical Trial Evaluating the Use of Adjuvant Endocrine Therapy One Year of Everolimus in Patients with High Risk Hormone Receptor Positive and HER2 neu Negative Breast Cancer CTO 101972 RTOG 0924 Active Enrolling Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer A Phase III Randomized Trial CTO 101977 RTOG 0815 Active Enrolling A Phase III Prospective Randomized Trial of Dose Escalated Radiotherapy With or Without Short Term Androgen Deprivation Therapy for Patients with Intermediate Risk Prostate Cancer CTO 102011 SWOG 1202 Active Enrolling A Randomized Placebo Controlled Phase III Study of Duloxetine for Treatment of Aromatase Inhibitor Associated Musculoskeletal Symptoms in Women with Early Stage Breast Cancer CTO 102046 ECOG E1Z11 Active Enrolling A Cohort Study to Evaluate Genetic Predictors for Aromatase Inhibitor Musculoskeletal Symptoms AIMSS CTO 102177 NRG GOG 0225 Active Enrolling Can Diet and Physical Activity Modulate Ovarian Fallopian Tube and Primary Peritoneal Cancer Progression Free Survival CTO 102162 A151216 Active Enrolling Adjuvant Lung Cancer Enrichment Marker Identificati and Sequencing Trial ALCHEMIST CTO 102163 A081105 Active Enrolling Randomized Double Blind Placebo Controlled Study of Erlotinib or Placebo in Patients with Completely Resected Epidermal Growth Factor Receptor EGFR Mutant Non Small Cell Lung Cancer NSCLC CTO 102164 E4512 Active Enrolling A Phase III Double Blind Trial for Surgically Resected Early Stage Non Small Cell Lung Cancer Crizotinib Versus Placebo for Patients with Tumors Harboring the Anaplastic Lymphoma Kinase ALK Fusion Protein CTO 102188 NRG BR001 Activation Pending A Phase I Study of Stereotactic Body Radiotherapy SBRT for the Treatment of Multiple Metastasis CTO 102193 NSABP B 55 Activation Pending A Randomised Double Blind Parallel Group Placebo

    Original URL path: http://hcc.musc.edu/se/util/display_mod.cfm?MODULE=/se-server/mod/modules/semod_printpage/mod_default.cfm&PageURL=/commitments/clinicaltrialsnetwork/members/selfregional.htm&VersionObject=4AD061C52D744DCC395BCF8B325DE38A&Template=17520059DFD5952C4D19749FE551BCCC&PageStyleSheet=3EA2F307D17F9983F24D78873A83FD01 (2015-11-11)
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