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  • Notre Dame News // University of Notre Dame
    disease that has no cure or treatment Lysomics is based on the work of Notre Dame professors of chemistry and biochemistry Olaf Wiest and Paul Helquist and Frederick Maxfield at Cornell University s Weill Medical College to find treatments for NPC NPC disease is a rare fatal neurodegenerative disease that primarily strikes children before and during adolescence Full Story View All Newswire Stories ND Newswire Ten Notre Dame faculty members named AAAS fellows Wiliam G Gilroy Date November 29 2012 Ten University of Notre Dame faculty members have been named fellows of the American Association for the Advancement of Science AAAS in honor of their efforts toward advancing science applications that are deemed scientifically or socially distinguished AAAS founded in 1848 as a nonprofit association is the world s largest scientific society and publisher of the prestigious journal Science Full Story View All Newswire Stories Live Look Featured Video When she was just 15 years old current Notre Dame sophomore Caitlin Crommet founded DreamCatchers a volunteer organization that works with hospice care professionals to fulfill the dreams of terminally ill patients Today thanks to support from Notre Dame s Hesburgh Yusko Scholars Program the sophomore s vision of fulfilling the dreams of others is now active in 10 states and counting Watch Video on YouTube See All Videos ND Experts Mary Ellen O Connell Areas of expertise International law international legal regulation of the use of force conflict and dispute resolution Complete Profile All Experts Anita Kelly Areas of expertise Secrets confidentiality Complete Profile All Experts George A Lopez Areas of expertise Peace studies economic sanctions repression and human rights violations ethics and the use of force Complete Profile All Experts Robert Schmuhl Areas of expertise American culture journalistic ethics journalism American politics and the media Complete Profile All Experts

    Original URL path: http://newsinfo.nd.edu/ (2012-12-02)
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  • Eck Institute’s Weinstein Lecture to take place Dec. 5 // News // Notre Dame News // University of Notre Dame
    Western Reserve University School of Medicine will present the lecture titled Mosquitoes Pathogens and Human Populations Global Health Research from the Laboratory to the Real World The lecture is free and open to the public Kazura s work focuses on the advancement of fundamental knowledge of the mechanisms underlying susceptibility to infection and the pathogenesis of disease due to malaria and chronic worm infections endemic in tropical areas of the world The ultimate goal is to use this knowledge to develop preventive and interventional strategies that are culturally appropriate and cost effective In addition to his research Kazura has been active in promoting tropical medicine as a scholarly and scientific discipline through participation on numerous National Institutes of Health and World Health Organization committees and other venues such as editorial service on major tropical disease journals Weinstein a leading authority on parasitology vector biology and public health joined the department of biological sciences at Notre Dame in 1969 as a professor and department chair For more than 21 years he was an exceptional researcher teacher and mentor Reflecting his passion for research he continued working and publishing after his retirement from teaching in 1990 until his death in 2008 Throughout his career he pursued research to understand and combat parasites responsible for problems such as blindness and elephantiasis The Eck Institute established the lecture in 2011 in recognition of the excellence that Weinstein brought to a life dedicated to advancing research on infectious diseases and training multiple generations of scientists The lecture will alternate with the George B Craig Memorial Lecture Series and be delivered by scholars or policymakers who have contributed significantly to global health Contact Sarah Craig 574 631 2665 Craig 20 nd edu News Eck Institute s Weinstein Lecture to take place Dec 5 Researchers collaborate to

    Original URL path: http://newsinfo.nd.edu/news/35964-eck-institutes-weinstein-lecture-to-take-place-dec-5/ (2012-12-02)
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  • Researchers collaborate to seek FDA approval for drug treatment for rare disease // News // Notre Dame News // University of Notre Dame
    Notre Dame and Cornell University have demonstrated the effectiveness of small molecule histone deacetylase inhibitors HDACi in correcting the NPC phenotype in human patient cells by increasing expression of the NPC1 protein The group is focusing on vorinostat an FDA approved anti cancer treatment Lysomics which is seeking FDA approval to repurpose vorinostat to treat NPC will soon submit an Investigational New Drug application The existing FDA approval of this drug has previously established its safety in humans and means that several expensive steps are not required Initial clinical trials could start next year Lysomics is considering clinical collaborations with the National Institutes of Health and other clinical centers for the Phase 1 trials NPC a genetic disease affects fewer than 100 people in the United States and an estimated 20 40 who are in the early stage of the disease could benefit from the treatment Most patients die by the age of 16 and few survive beyond 25 The disorder prevents their bodies from processing cholesterol which accumulates in the brain Vorinostat is most effective in the early stages of NPC although it could improve quality of life for older patients The effort will benefit from the 30 year old Orphan Drug Act which helps development of treatments for conditions that affect fewer than 200 000 people in the United States The federal law grants exclusive marketing for seven years after FDA approval tax credits of 40 percent for clinical research expenses grants for studies up to 200 000 per year for three years and a waiver of a high filing fee Lysomics from the onset was a not for profit operation said Wiech the company s CEO You can t get a drug approval unless you re a company A company has to be structured so it can

    Original URL path: http://newsinfo.nd.edu/news/35961-researchers-collaborate-to-seek-fda-approval-for-drug-treatment-for-rare-disease/ (2012-12-02)
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  • Ten Notre Dame faculty members named AAAS fellows // News // Notre Dame News // University of Notre Dame
    the yoctomole level and chemical cytometry Crislyn D Souza Schorey A major focus of D Souza Schorey s research is to define how altered regulation of signaling pathways that govern cells can contribute to cancer initiation and progression She was cited for distinguished contributions to the field of cancer cell biology particularly for studies on membrane traffic and ARF proteins in cell motility and tumor invasion Jeffrey Feder Feder s research is focused on understanding speciation the process whereby one evolutionarily distinct gene pool is divided into two He was cited for distinguished contributions to evolutionary biology in advancing our understanding of ecological adaptation and speciation and in particular to speciation occurring with gene flow Harindra Joseph Shermal Fernando Fernando is an expert in fluid mechanics specifically in atmospheric and oceanic flows as well as industrial flows involving density variations He was cited for excellent research on experimental and theoretical fluid dynamics with insightful applications to real world problems such as tsunamis urban flows and mountain winds Stefan Frauendorf Frauendorf s research interests involve the theoretical study of the newfound phenomena that challenge the traditional understanding of the atomic nucleus He was cited for seminal contributions to understanding the collective motion of heavy atomic nuclei in particular when axial symmetry is broken Peter Garnavich Garnavich s research interests cover a wide range of topics in observational astrophysics A primary focus has been the study of supernovae and their diversity He was cited for pioneering work on the discovery of dark energy and the cosmic equation of state along with important observational discoveries regarding gamma ray bursts and the physics of supernova light curves Randal Ruchti The objective of Ruchti s research program is the study of the fundamental questions at the high energy frontier TeV Scale with particular emphasis on experiments performed at hadron colliders He was cited for pioneering work in the development of scintillating fiber detectors in high energy physics and for major contributions to particle physics education and outreach Jeffrey Schorey Schorey s research focuses on the interaction between mycobacteria which have a long history as pathogenic organisms and are the etiological agents of such diseases as tuberculosis and leprosy and its host cell the macrophage He was cited for notable contributions to the field of mycobacterial pathogenesis particularly to our understanding of the dynamic interaction between mycobacteria and its host cell the macrophage Stack s current research centers on the proteinase families in two model systems epithelial ovarian carcinoma and squamous cell carcinoma of the oral cavity She was cited for distinguished contributions to the field of proteinase regulation including mechanisms of post translational regulation of pericellular proteolysis via cell cell and cell matrix adhesion Olaf Wiest Wiest s research interests include computational and physical organic chemistry computational drug design biophysical chemistry enzyme mechanisms transition metal catalyzed reactions and design of ligands for enantioselective catalysis He was cited for contributions to interdisciplinary studies in computational chemistry inorganic chemistry and drug design The tradition of AAAS fellows

    Original URL path: http://newsinfo.nd.edu/news/35934-ten-notre-dame-faculty-members-named-aaas-fellows-2/ (2012-12-02)
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  • Mary Ellen O'Connell // Notre Dame News // University of Notre Dame
    international law and an answer to those who deny its status as law VIDEOS ND EXPERTS Al Awlaki killing was illegal U S is most definitely involved in hostilities in Libya Standing by the rule of law in terrorism trials Law School s O Connell comments on al Marri charges Law School s O Connell praises Bush decision not to assist attack on Iran Law School s O Connell urges Guantanamo closing Law School Professor O Connell extols international law Law School s O Connell assesses legality of Caucasus war Law scholar supports World Court order to halt executions Law professor Mary Ellen O Connell ponders international responsibility in Darfur crisis U S must not dilute prisoner treatment policies ND NEWSWIRE ARTICLES Law professor launches book on international law Law School s O Connell testifies before Congress IN THE NEWS WTTW Unmanned Drones CNN When are drone killings illegal op ed The Guardian U K The legal dilemma over drone strikes justified killings or war crimes Miami Herald Families of killed al Qaida figures file wrongful death suit against U S officials Inter Press Service Families of U S Victims of Drone Attacks Sue Top Officials The Guardian US drone strikes in Yemen crucial to prevent terrorist threat Panetta says Rolling Stone The Rise of the Killer Drones How America Goes to War in Secret Russia Today As Masks Fall is Murder Inc the real face of the US BBC News How Iran might respond to Israeli attack Associated Press Holder gives legal defense for al Awlaki killing NPR Holder Spells Out Why Drones Target U S Citizens NPR Obama s Military Tactics Risky Missions Elite Units The Guardian Why Obama s targeted killing is worse than Bush s torture Al Jazeera Targeted killing and the War on Terror Washington

    Original URL path: http://newsinfo.nd.edu/for-the-media/nd-experts/faculty/mary-ellen-o-connell/ (2012-12-02)
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  • Anita Kelly // Notre Dame News // University of Notre Dame
    in thought suppression may lead to problems for some people but may be an effective thought control strategy for others Kelly is author of The Psychology of Secrets and has developed a model for when people should and should not reveal their secrets to various confidants ND EXPERTS Keeping secrets not always harmful ND NEWSWIRE ARTICLES Study Telling fewer lies linked to better health and relationships IN THE NEWS PBS Should Campaign Donors Be Disclosed Good Afternoon America GAA Toe to Toe Is Honesty the Best Policy Huffington Post Lying Why You Don t Tell The Truth And Why You Should Start NBC News Could you go 10 weeks without lying WCBS New York City Fewer Lies Better Health Chicago Sun Times Avoiding lies can help your health study finds Washington Times What can NASA s Curiosity Rover tell us about the future of health New York Daily News Little white lies may be bad for your health Chicago Sun Times Avoiding lies can help your health study finds Huffington Post Honesty Linked With Better Health Study Time Can Telling the Truth Make You Healthier The Daily Mail Honesty is the best policy as telling fewer lies improves your physical

    Original URL path: http://newsinfo.nd.edu/for-the-media/nd-experts/faculty/anita-kelly/ (2012-12-02)
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  • George A. Lopez // Notre Dame News // University of Notre Dame
    roadblock International Business Times Russia Reported Backing Annan s Unity Plan For Syria Bloomberg Russia Said to Endorse Replacing Assad in Turn From Ally Bloomberg Russia Must Drop Assad Before Talks U S Official Says Bloomberg Businessweek Russia Must Drop Assad Before Talks U S Official Says NPR Syria news update The Daily Beast Iraq War Sanctions Run Amok Shakir Hamoodi s Story MSNBC The Dylan Ratigan Show Will the US call Russias bluff on Syria CNN com The only glimmer of hope for Syria CNN International Syria and State Violence CNN com U S Russia grapple for common ground on Syria transition CNN International Syria and Sanctions CNN Anderson Cooper Keeping Syria s so called ceasefire New York Times Cease Fire in Syria Exposes Heavy Price of Just Buying Time CNN op ed Will Obama move thwart murderous regimes Reuters Obama seeks to stop Syria Iran tech assault on activists Christian Science Monitor op ed Bashar al Assad may be beating Annan plan in Syria for now but he won t for long FOX News com UN computer shipment to North Korean regime violates US manufacturer s ban CNN com Syria s al Assad gaining strength under U N moves experts say Associated Press Truce eroding as first UN monitors head to Syria New York Times In North Korea Deal Son Inherits Father s Framework Bloomberg North Korea Agrees to Halt Nuclear Tests Missile Launches Amid U S Talks The Guardian North Korea pledges to halt nuclear programme in exchange for US aid CNN op ed Russia and China Sabotaging UN with Vetoes Bloomberg Businessweek China s UN Veto on Syria May Not Hurt Relations With Persian Gulf Bloomberg Businessweek Iran Anxiety No Match for Central Bankers Sedating Traders With Cheap Cash Reuters Russia UN veto on Syria aimed at crushing West s crusade CNN International Syria violence and sanctions New York Times At UN pressure is on Russia for refusal to condemn Syria Reuters Analysis Oil reports may offer Obama an out on Iran Los Angeles Times U S Europe choose risky strategy with sanctions on Iran International Business Times Iran Sanctions Will They Work or Will They Backfire NPR com Syrians Cope With Economic Crisis Amid Uprising Huffington Post So Much Worse Than Civil War Reuters UK Iran sanctions push is test for West diplomacy Inter Press Service Syrian Leader Survives on Unrelenting Russian Chinese Support Businessweek Syrian ministers face Arab travel ban Associated Press Syrian ministers face Arab travel ban Wall Street Journal More Than 250 Children Among Dead U N Says Washington Post U N report documents Syria s gross violations of human rights New York Times Syria Calls Arab League Sanctions Economic War Christian Science Monitor Why Obama sees time as ripe for overture to Burma regime Businessweek Syria s Suspension From Arab League to Renew UN Sanctions Push New York Times With Rare Double U N Veto on Syria Russia and China Try to Shield Friend Business Week Russia Defends Top Mideast Ally

    Original URL path: http://newsinfo.nd.edu/for-the-media/nd-experts/faculty/george-lopez/ (2012-12-02)
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  • Robert Schmuhl // Notre Dame News // University of Notre Dame
    or editor of 11 books including Statecraft and Stagecraft American Political Life in the Age of Personality which describes the cult of personality taking over politics and Wounded Titans American Presidents and the Perils of Power VIDEOS ND EXPERTS Obama campaign getting a good deal on text messaging plan Oprah Obama and celebrity politics Presidential primaries system chaotic and broken Schmuhl criticizes primary system Obama forms exploratory committee surprising similarities between senator and Reagan ND NEWSWIRE ARTICLES Schmuhl to deliver keynote address at Dublin conference Schmuhl to serve as visiting fellow at University College Dublin Robert Schmuhl receives Media Legend of the Year award Quotable around the globe New book by Robert Schmuhl praised in Chicago Tribune review National Press Club to feature Robert Schmuhl s latest book American studies professor publishes essay collection Annenberg gift strengthens journalism at Notre Dame IN THE NEWS Independent ie but things were different in Nixon s time Louisville Courier Journal Keeping options open former Indiana Sen Evan Bayh hangs on to campaign money Independent ie Robert Schmuhl We have to ask the question did Obama really reach out enough Morning Ireland Debate was a bare knuckle political fight Notre Dame Professor Robert Schmuhl Indianapolis Star Election 2012 Indiana political scientists sift through aftermath of Obama Romney debate Richard Mourdock Joe Donnelly clash in U S Senate debate Senate debate highlights differences Fort Wayne Journal Gazette GOP wild card in U S Senate race Huffington Post Mitt Romney s Wawa Gaffe Just Latest Out Of Touch Politician Moment Bill Moyers The President s Never Ending Campaign for Cash Washington Post Celebrity as campaign necessity Obama campaign raffles access to stars in fight for money UPI Politics 2012 Indiana North Carolina West Virginia kick off final round of primaries Morning Ireland RTÉ US presidential candidates

    Original URL path: http://newsinfo.nd.edu/for-the-media/nd-experts/faculty/robert-schmuhl/ (2012-12-02)
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