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  • hypothalamus | Newswire
    the Howard Hughes Medical Institute HHMI at The Rockefeller University in the Feb 15 Nature More Tags hypothalamus Jeffrey M Friedman Ob R October 31 1995 Science News Leptin Helps Body Regulate Fat Links to Diet Leptin a protein produced by fat appears to play an important role in how the body manages its supply of fat report scientists in the November Nature Medicine More Tags hypothalamus Jeffrey M Friedman

    Original URL path: http://newswire.rockefeller.edu/tag/hypothalamus/ (2016-02-13)
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  • Japanese Government Honors Rockefeller University Professor for Cancer Research | Newswire
    then investigators in many groups including Hanafusa s have identified more than 40 oncogenes In his early work Hanafusa noted that tumor causing viruses stripped of all the genetic material needed to form tumors still induced cancer in animal cells Hanafusa found the viruses reacquired the missing gene an oncogene from the cells normal genetic material The experiments also demonstrated that the viruses used the oncogene to produce tumors Specifically the oncogene inappropriately stimulated normal cell genes to overproduce their protein products In these experiments Hanafusa used the Rous sarcoma virus named for its discoverer Peyton Rous M D a Rockefeller scientist and Nobel laureate Hanafusa s current research focuses on the structure and function of oncogenes the proteins they make and how these genes regulate other genes in a cell Some oncogene proteins are enzymes that regulate basic cell functions His group analyzes the biochemical properties of such enzymes and how they influence cell growth and metabolism Recently one of these studies led to the discovery of particular protein domains named SH2 and SH3 which play pivotal roles in protein interactions related to cell growth Understanding the cell functions of oncogenes is key to elucidating the processes involved in cancer Hanafusa was born Dec 1 1929 in Nishinomiya Japan He received his bachelor of science degree in 1953 and a doctoral degree in biochemistry in 1960 both from Osaka University in Japan As a research associate at Osaka University s Research Institute for Microbial Diseases between 1958 and 1961 Hanafusa studied poxviruses From 1961 to 1964 he researched RNA tumor viruses at the University of California Berkeley first as a postdoctoral fellow and then as an assistant research virologist Also from 1962 to 1964 Hanafusa was a visiting scientist at the College de France in Paris From 1966 until

    Original URL path: http://newswire.rockefeller.edu/1995/10/26/japanese-government-honors-rockefeller-university-professor-for-cancer-research/ (2016-02-13)
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  • Hidesaburo Hanafusa | Newswire
    will present Japan s Order of Culture to cancer researcher Hidesaburo Hanafusa Ph D Leon Hess Professor at The Rockefeller University in a ceremony at the Imperial Palace in Tokyo on Friday Nov 3 More Tags Hidesaburo Hanafusa Japan s Order of Culture Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011 more About Contact Follow rockefelleruniv Like The

    Original URL path: http://newswire.rockefeller.edu/tag/hidesaburo-hanafusa/ (2016-02-13)
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  • Japan’s Order of Culture | Newswire
    government will present Japan s Order of Culture to cancer researcher Hidesaburo Hanafusa Ph D Leon Hess Professor at The Rockefeller University in a ceremony at the Imperial Palace in Tokyo on Friday Nov 3 More Tags Hidesaburo Hanafusa Japan s Order of Culture Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011 more About Contact Follow rockefelleruniv Like

    Original URL path: http://newswire.rockefeller.edu/tag/japans-order-of-culture/ (2016-02-13)
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  • Lecture: How Many People Can the Earth Support? | Newswire
    rate seen in 1990 the world population would tally 694 billion by the year 2150 But that s not likely More realistic says Cohen are estimates between 4 and 20 billion people Why Come hear Cohen author of the forthcoming book How Many People Can the Earth Support due this December from W W Norton Company as he discusses how human choices about economies environment values and politics are just

    Original URL path: http://newswire.rockefeller.edu/1995/10/20/lecture-how-many-people-can-the-earth-support/ (2016-02-13)
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  • overpopulation | Newswire
    1995 Campus News Lecture How Many People Can the Earth Support Come hear Joel E Cohen M P H Ph D Dr P H professor and director of the Laboratory of Populations at The Rockefeller University and author of the forthcoming book How Many People Can the Earth Support due this December from W W Norton Company as he discusses how human choices about economies environment values and politics are

    Original URL path: http://newswire.rockefeller.edu/tag/overpopulation/ (2016-02-13)
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  • Neuroscientist A. James Hudspeth Joins Rockefeller Faculty | Newswire
    hearing through his elegant studies of the mechanisms used by hair cells to transmit sound waves as cellular signals says Torsten Wiesel M D president of Rockefeller He will enrich our campus not only in neurobiology and biophysics but in all of our scientific and educational activities In his research Hudspeth explores how hair cells inside the ear relay sound to the brain He recently isolated the gene carrying the instructions to make a protein found on the top of sound sensitive hair bundles which may play a role in the amplifying of sound Hudspeth comes to Rockefeller after serving as professor and director of the neuroscience program at the University of Texas Medical Center in Dallas Hudspeth received his bachelor of arts degree in 1967 from the Biochemical Sciences Program at Harvard College in Boston Mass and a master of arts degree in 1968 and a doctoral degree in 1973 from the Division of Medical Sciences at the Harvard Graduate School of Arts and Sciences In 1974 he earned a medical degree from the Harvard Medical School In addition to his post at the University of Texas Hudspeth has held teaching positions at Harvard Medical School Cold Spring Harbor Laboratory the California Institute of Technology and the University of California School of Medicine While at the University of Texas Hudspeth served as professor and chairman of the Department of Cell Biology and Neuroscience and founded the school s neuroscience program A member of the National Academy of Sciences Hudspeth has received honors for his research from Columbia University the New York Academy of Sciences the National Institutes of Health and the Dana Foundation He also received awards for excellence in teaching from the California Institute of Technology the University of California and the University of Texas Hudspeth serves as

    Original URL path: http://newswire.rockefeller.edu/1995/10/16/neuroscientist-a-james-hudspeth-joins-rockefeller-faculty/ (2016-02-13)
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  • Fat, Body Weight Regulated by Newly Discovered Hormone | Newswire
    has proven to be a wise one Defects in the ob gene result in massive obesity in mice as part of a syndrome that resembles obesity in humans The new findings indicate that when ob is defective leptin is not made and does not transmit its signal to stop eating says lead author Jeffrey L Halaas biomedical fellow at Rockefeller Consequently mice with a faulty ob gene are overweight and have a form of diabetes The scientists now are seeking to understand how leptin transmits its weight reducing signal Friedman notes the hypothalamus the part of the brain that coordinates basic bodily functions such as food intake is likely to receive leptin s signal either directly or indirectly Obesity defined as being more than 20 percent over an ideal weight is a major risk factor for diabetes heart disease high blood pressure stroke sleep apnea gallstonesas well as some cancers and forms of arthritis In the United States more than one third of adults 50 million people are obese reports the National Institute of Diabetes and Digestive and Kidney Diseases NIDDK which with the U S Public Health Service supported the study In the last 10 years the number of overweight Americans has increased from 25 to 34 percent While diet and exercise are presently the cornerstone of weight control this new molecular approach to understanding the regulation of body weight is one of the best examples of real progress in biomedical research says Phillip Gorden M D director of NIDDK which is part of the National Institutes of Health The researchers measured the amounts of leptin in mouse blood and found that mice with a defective ob gene do not make the hormone Another kind of obese mouse with a defective gene called diabetes db has levels 10 times greater than normal mice The db mice are thought to have a defective leptin receptor Receptors are specialized proteins that receive cellular signals The investigators also found leptin in the blood of six lean humans In a four week mouse study the investigators gave sets of 10 ob db and normal mice daily injections of mouse leptin made in the laboratory by inserting the ob gene into bacteria Each of the mice received 5 milligrams leptin per kilogram of body weight For comparison control mice received either injections of a salt solution or no treatment The effect of the laboratory derived leptin on food intake and body weight in mice is dramatic says Burley After two weeks of treatment with leptin the ob mice lost 30 percent of their body weight without side effects The reduced weight in these mice also came exclusively from fat loss For example at the end of the study treated ob mice had 9 1 grams of fat while untreated ob mice had 38 30 grams of fat A normal healthy adult mouse has between 2 and 5 grams of fat In contrast leptin had no effect on the db mice The failure of leptin

    Original URL path: http://newswire.rockefeller.edu/1995/07/27/fat-body-weight-regulated-by-newly-discovered-hormone/ (2016-02-13)
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