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  • Discovery reveals protons sneak through the sodium-potassium pump | Newswire
    thought to happen only when the pump was deprived of its normal cargo sodium and potassium ions Gadsby says But now we have shown by very careful measurements that protons can flow through these pumps under normal conditions Scientists have known for decades the pump moves two potassium ions into the cell for every three sodium ions it transports out Since cells contain a higher concentration of potassium than is outside the cell but less sodium than is located outside this process requires energy The ions carry an electrical charge so this movement contributes to an electrical gradient or a difference in electrical potential between the inside and outside of the membrane in which the pump is located These concentration and potential gradients power electrical signals used to send messages or contract muscles within the body Working with unfertilized frog eggs Gadsby and postdoc Natascia Vedovato discovered that under normal conditions protons which are positively charged flow into the cell by hijacking a spot in the pump otherwise reserved for sodium Every time a pump goes through a cycle pushing three sodium ions out and bringing two potassium ions in there is a chance a proton from outside the cell will find its way into a vacant sodium binding site and from there into the cell We do not yet know if this is simply an unavoidable byproduct of the conformation changes that must occur in the pump or if the proton import is a side job that serves a useful function in some location at some time and so has been preserved by evolution Gadsby says Under normal conditions the probability that a proton will get in is quite low but the protons chances increase when the environment outside the cell becomes more acidic when more protons are available

    Original URL path: http://newswire.rockefeller.edu/2014/03/31/discovery-reveals-protons-sneak-through-the-sodium-potassium-pump/ (2016-02-13)
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  • david gadsby | Newswire
    than just the sodium and potassium that its name would suggest New research shows these pumps also routinely transport hydrogen ions known as protons Among other things the work suggests a new dimension to molecules that underlie processes involved in nerve signaling and muscle contractions More Tags david gadsby membrane proteins protons sodium potassium pump Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive

    Original URL path: http://newswire.rockefeller.edu/tag/david-gadsby/ (2016-02-13)
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  • protons | Newswire
    than just the sodium and potassium that its name would suggest New research shows these pumps also routinely transport hydrogen ions known as protons Among other things the work suggests a new dimension to molecules that underlie processes involved in nerve signaling and muscle contractions More Tags david gadsby membrane proteins protons sodium potassium pump Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive

    Original URL path: http://newswire.rockefeller.edu/tag/protons/ (2016-02-13)
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  • sodium-potassium pump | Newswire
    more than just the sodium and potassium that its name would suggest New research shows these pumps also routinely transport hydrogen ions known as protons Among other things the work suggests a new dimension to molecules that underlie processes involved in nerve signaling and muscle contractions More Tags david gadsby membrane proteins protons sodium potassium pump Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video

    Original URL path: http://newswire.rockefeller.edu/tag/sodium-potassium-pump/ (2016-02-13)
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  • 23 students receive Ph.D.s at Rockefeller’s 53rd commencement | Newswire
    receiving their degrees Recipients of the doctoral degrees are Erika Dewyllie Billick Anne Helen Bothmer Michael Chiorazzi Nicole Creanza Shelli F Farhadian Robert Jonathan Fenster Zak Frentz Felice Kelly Jeffrey Hoon Kim Adria Claire Le Boeuf Geulah Livshits Tapan Apurva Maniar Catherine Oikonomou Grigorios Oikonomou Margherita Peliti Maurizio Pellegrino Andrea Geoghegan Procko Jonathan E Schmitz Jason Schwarz Matthew Sekedat Alice O Kamphorst Silva Clare Walton and John Paul Wilson Richard Axel doctor of science honoris causa has integrated molecular biology to problems in neuroscience with the expectation that genetics could interface with neuroscience to approach the tenuous relationship between genes behavior and perception His studies on the logic of the sense of smell revealed over a thousand genes involved in the recognition of odors and provided insight into how genes shape our perception of the sensory environment For a series of pioneering studies that clarified in exquisite detail how the sense of smell works he shared the 2004 Nobel Prize in Physiology or Medicine with Buck Linda B Buck doctor of science honoris causa studies exactly how odor molecules in the environment are detected by specialized receptors in the nose and then translated by the brain into specific smells Her

    Original URL path: http://newswire.rockefeller.edu/2011/06/16/23-students-receive-ph-d-s-at-rockefellers-53rd-commencement/ (2016-02-13)
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  • Twenty-eight degrees awarded at Rockefeller’s 48th convocation | Newswire
    of graduate studies for 28 students Twenty six of this year s 28 graduates participated in a formal presentation of Ph D s held in Caspary Auditorium on the university s Manhattan campus President Paul Nurse and Chair of the Board Russ Carson presided over the ceremony In addition to the graduate degrees two honorary degrees were awarded to Shirley Tilghman president of Princeton University and Bruce Alberts professor of biochemistry at the University of California San Francisco The David Rockefeller Award for Extraordinary Service was also presented to retired Executive Vice President Fred Bohen The Rockefeller University Class of 2006 is Pinar Akpinar James M Bean Catharine E Boothroyd Dylan Kar Shuen Chan Emmanuel J Chang Anna Charalambous M Eugenia Chiappe Oliver Dreesen Elane Fishilevich Jedidiah Gaetz Armin M Gamper Svetlana Gorokhova Véronique Haegeli Daylon Jefferson James Randy Scott Longman Kara N Maxwell Lubomir Merkov Vasant Muralidharan Tetyana Obukhanych Elliot A Perens Xenia O Protopopescu Srihari C Genevieve S Yuen Tags convocation newswire rockefeller edu Contact Joseph Bonner 212 327 8998 Human stem cells can contribute to a developing mouse embryo despite evolutionary differences Nine Rockefeller labs to receive Stem Cell Initiative grants Comments are closed Search for Categories

    Original URL path: http://newswire.rockefeller.edu/2006/07/16/twenty-eight-degrees-awarded-at-rockefellers-48th-convocation/ (2016-02-13)
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  • Rockefeller University Honors William O. Baker, Presents Honorary Degrees to Irene Diamond and Christian de Duve and Awards 21 Doctorates at Graduation Ceremonies | Newswire
    College in 1935 and his doctorate in physical chemistry from Princeton University in 1938 Diamond Receives Doctor of Laws honoris causa Diamond is president of The Irene Diamond Fund Inc and was the president of the Aaron Diamond Foundation until its close in December 1996 The Aaron Diamond Foundation s emphasis on medical research programs made it the United States largest private supporter of AIDS research In 1991 the foundation established the Aaron Diamond AIDS Research Center for the City of New York directed by David Ho M D professor at Rockefeller A native of Pittsburgh Diamond pursued a film industry career in New York City and Hollywood Calif becoming a senior story and talent editor for Warner Brothers Samuel Goldwyn and Paramount Pictures Among her credits during many years work with the producer Hal Wallis is the purchase and development of the scripts for Come Back Little Sheba The Rose Tattoo and Casablanca Along with her husband Aaron a New York real estate developer Irene established the Aaron Diamond Foundation in the 1955 Later the Diamonds determined that the foundation should exist for 10 years after its major funding was in place which occurred in January 1987 The foundation spent 220 million over 10 years mostly in New York City In addition to the support of the Diamond AIDS Research Center the foundation created a 20 million postdoctoral research fellowship program for young scientists in the AIDS and drug abuse fields and was a major supporter of new programs and the smaller New Visions schools in the public school system and of the arts human rights and civil liberties The new Irene Diamond Fund will work in AIDS and immunology and in the performing arts de Duve Receives Doctor of Science honoris causa de Duve is the Andrew W Mellon Professor Emeritus at Rockefeller and president of the International Institute of Cellular and Molecular Pathology ICMP in Belgium A biochemical cytologist de Duve has investigated the separation and characterization of the different parts or organelles of living cells He discovered lysosomes subcellular particles that function in the digestive system of the cell in 1949 In 1974 he shared the Nobel Prize in Physiology or Medicine with Albert Claudeand George E Palade of Rockefeller for discoveries concerning the structural and functional organization of the cell He has received numerous other honors and awards He joined the Rockefeller faculty in 1962 maintaining a part time appointment with the University of Louvain where he now is a professor emeritus In 1975 he created the ICMP He is the author of three books A Guided Tour of the Living Cell Blueprint of a Cell and Vital Dust Life as A Cosmic Imperative A citizen of Belgium de Duve is a native of England He received his degree of doctor of medicine surgery and obstetrics in 1941 the Agregation de l Enseignement Superieur the equivalent of a doctorate in 1945 and a master of science degree in chemistry in 1946 all from the University

    Original URL path: http://newswire.rockefeller.edu/1997/06/12/rockefeller-university-honors-william-o-baker-presents-honorary-degrees-to-irene-diamond-and-christian-de-duve-and-awards-21-doctorates-at-graduation-ceremonies/ (2016-02-13)
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  • William O. Baker | Newswire
    University will honor William O Baker Ph D former chairman of the board of AT T Bell Laboratories Inc and award honorary doctoral degrees to philanthropist Irene Diamond and Nobel Prize winner Christian de Duve Ph D M D at the institution s 39th commencement exercises Thursday June 12 1997 More Tags graduation William O Baker Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video

    Original URL path: http://newswire.rockefeller.edu/tag/william-o-baker/ (2016-02-13)
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