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  • Awards and Honors | Newswire | Page 3
    and Honors Huda Y Zoghbi pediatric neurologist to receive 2013 Pearl Meister Greengard Prize Huda Y Zoghbi M D a pediatric neurologist and neuroscientist who has worked on the genetic underpinnings of rare neurological diseases and advanced our understanding of brain disorders has been selected to receive the tenth annual Pearl Meister Greengard Prize one of the world s preeminent honors recognizing outstanding achievements by women in science More June 28 2013 Awards and Honors James E Darnell Jr elected to membership in American Philosophical Society The society founded by Benjamin Franklin in 1743 it is the United States first learned society and unique among its peers for the wide variety of academic disciplines represented by its membership Darnell is the university s tenth faculty member to be inducted into the society More Tags American Philosophical Society James E Darnell Jr June 20 2013 Awards and Honors Jonathan Fisher receives Blavatnik Award for Young Scientists Fisher is a postdoc in James Hudspeth s Laboratory of Sensory Neuroscience studying the biophysics and neurophysiology of the auditory system He is one of seven winners of the prize which is given to faculty and postdocs in the tri state area More Tags Blavatnik Awards June 14 2013 Awards and Honors Paul Nurse receives Albert Einstein World Award of Science President emeritus and head of the Laboratory of Yeast Genetics and Cell Biology at Rockefeller Nurse is being honored by the World Cultural Council for his long term work as scientific leader committed to excellence in learning research health and education More Tags Paul Nurse World Cultural Council May 30 2013 Awards and Honors Mike Young to receive Shaw Prize Young and two colleagues will be awarded the 2013 Shaw Prize in Life Science and Medicine worth 1 million Established in 2002 the Shaw Prize honors individuals who have achieved breakthroughs in academic and scientific research or applications and whose work has resulted in a positive and profound impact on humanity More May 9 2013 Awards and Honors Jean Laurent Casanova appointed HHMI investigator Casanova whose research established for the first time that a predisposition to infectious diseases in children can be genetically determined has been named one of 27 new investigators with the Howard Hughes Medical Institute His appointment brings the total number of Rockefeller scientists supported by HHMI to 16 More Tags HHMI Jean Laurent Casanova May 7 2013 Awards and Honors Lewis Thomas Prize to be awarded to Kay Redfield Jamison Jamison a professor of psychiatry at The Johns Hopkins University School of Medicine has made extensive contributions to the field of psychology and is considered one of the country s foremost authorities on manic depressive bipolar illness She is being honored for her 1993 book Touched with Fire Manic Depressive Illness and the Artistic Temperament which examines the relationship between artistic creativity and mood disorders More April 24 2013 Awards and Honors Marc Tessier Lavigne and Jeffrey Friedman elected to American Academy of Arts and Sciences Tessier Lavigne Rockefeller president

    Original URL path: http://newswire.rockefeller.edu/category/awards-and-honors/page/3/ (2016-02-13)
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  • Jean-Laurent Casanova honored with 2014 Sanofi-Institut Pasteur Award | Newswire
    the life sciences Two international awards were made this year the Senior Award and the Mid career Award As this year s Mid career Award winner Casanova will receive approximately 35 000 and his laboratory will receive about 65 000 The awardees will be honored at a ceremony on November 13 in Paris France Etienne Pays a parasitologist from Université libre de Bruxelles is the Senior Award winner In his pioneering research Casanova and his colleagues discovered holes in the immune systems of otherwise healthy children that make them susceptible to specific sometimes life threatening infectious diseases These holes are caused by congenital mutations in a single gene and are responsible for susceptibility to certain infections including mycobacterial diseases herpes simplex virus encephalitis invasive pneumococcal disease chronic mucocutaneous candidiasis and Kaposi sarcoma The practical implementations of these findings include molecular diagnosis and genetic counseling for the patients and their families as well as the development of targeted therapies with recombinant cytokines aimed at restoring a deficient immune response Casanova has been at Rockefeller since 2008 and has been a Howard Hughes Medical Institute investigator since 2014 In recent years Casanova s research has been recognized with numerous awards He was the recipient of the Professor Lucien Dautrebande Pathophysiology Foundation Prize in 2004 the Richard Lounsbery Award in 2008 the InBev Baillet Latour Health Prize in 2011 the Ilse and Helmut Wachter Foundation Award in 2012 and the Robert Koch Prize in 2014 The prize is given jointly by Sanofi and the Institut Pasteur Sanofi a global pharmaceutical company based in France and the Institut Pasteur an internationally renowned biomedical research center created the awards in 2012 to promote scientific excellence in the service of health This year the prizes went to scientists who investigate tropical and neglected diseases immunology drug

    Original URL path: http://newswire.rockefeller.edu/2014/08/01/jean-laurent-casanova-honored-with-2014-sanofi-institut-pasteur-award/ (2016-02-13)
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  • Tri-Institutional Breakthrough Prize winners establish new award for postdocs | Newswire
    respective institutions the award will be sustained by a 3 million endowment The Tri Institutional Breakout Awards for Junior Investigators will be given to three to six outstanding postdoctoral trainees every year with each recipient receiving 25 000 One prize will be awarded to an applicant from each of the three founding institutions and additional awards will be given to the best candidates regardless of their institutional affiliation The inaugural winners will be announced by the end of 2014 We want to recognize and encourage the rising stars in science says Bargmann who is Torsten N Wiesel Professor and head of the Lulu and Anthony Wang Laboratory of Neural Circuits and Behavior With this prize for exceptional postdocs we can highlight their talent passion and accomplishment and celebrate exciting discoveries in our community The Breakthrough Prize in Life Sciences established by Art Levinson Sergey Brin Anne Wojcicki Mark Zuckerberg Priscilla Chan and Yuri Milner recognizes excellence in research aimed at curing intractable diseases and extending human life Eleven inaugural winners each received 3 million to advance breakthrough research celebrate scientists and generate excitement about the pursuit of science as a career Bargmann was recognized for her work on the genetics

    Original URL path: http://newswire.rockefeller.edu/2014/05/12/tri-institutional-breakthrough-prize-winners-establish-new-award-for-postdocs/ (2016-02-13)
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  • Hunt for Early Heart Attack Genes Begins | Newswire
    evidence that heart disease including heart attacks runs in families Heart attacks result from a person s complex genetic makeup and his or her interactions with the environment including what he or she eats how much he or she exercises and if he or she smokes While we know a great deal about the influence of diet exercise and cigarettes on heart disease we do not yet know the identity of genes that would explain susceptibility to heart attacks explains coinvestigator Elizabeth De Oliveira e Silva M D research associate at Rockefeller To locate and determine the structure and function of one or more genes involved in heart attacks the scientists will examine blood samples and medical histories of 2 000 people who have heart attacks at an early age Because heart disease is likely to have various genetic causes enrolling such a large study population will help the scientists hunt for several genes at the same time notes Breslow Frederick Henry Leonhardt Professor and a senior physician at The Rockefeller University Hospital Specifically they will recruit men who had a first heart attack before age 45 and women before age 55 men who had a first heart attack before age 55 and have a living sibling who has had a first heart attack before 55 brothers or before 65 sisters women who had a first heart attack before age 65 and have a living sibling who had a first heart attack before 55 brothers or before 65 sisters People interested in enrolling as participants should call Mary Lou Klimek M A R N at 1 888 920 9100 or 212 327 7445 for more information All information is kept confidential People accepted into the study will be offered free blood cholesterol and lipoprotein analysis and information about modifying their

    Original URL path: http://newswire.rockefeller.edu/1997/09/16/hunt-for-early-heart-attack-genes-begins/ (2016-02-13)
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  • heart disease | Newswire
    the number of receptors on liver cells that remove the bad LDL cholesterol from the blood More Tags cholesterol heart disease Jan L Breslow November 26 2003 Science News Genes may protect against heart disease rather than be harmful as previously thought A genetic pathway whose activity was suspected to advance heart disease by increasing inflammation in the blood vessels and arteries feeding the heart may actually protect against it at least in laboratory mice reports a team of Rockefeller University scientists led by Jan Breslow M D in the Nov 25 issue of Proceedings of the National Academy of Sciences More Tags heart disease Jan L Breslow July 24 2001 Campus News Rockefeller Heart Disease Study Seeks Patients A new study at The Rockefeller University Hospital will assess the potential of a fatty acid found in fish to reduce heart attack risk The researchers are testing the hypothesis that a daily dose of the omega 3 fatty acid known as DHA will positively alter heart disease risk factors in at risk individuals specifically overweight and obese people Participants who meet certain weight and health criteria are currently being enrolled in the clinical trial More Tags heart disease Jan L

    Original URL path: http://newswire.rockefeller.edu/tag/heart-disease/ (2016-02-13)
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  • Jan L. Breslow | Newswire
    work has direct clinical consequences to patients under long term treatment of PXR activating drugs including several antibiotic and anti cancer medications and your daily latte More Tags Jan L Breslow Laboratory of Biochemical Genetics and Metabolism December 16 2008 Science News Single letter in the human genome points to risk for high cholesterol In the search for genes that affect how humans synthesize process and break down cholesterol a consortium of researchers led by Rockefeller University scientists has found a single letter in the genome that is associated with elevated LDL cholesterol levels one of the leading health concerns that has come to dominate the 21st century More Tags cholesterol Jan L Breslow February 12 2007 Campus News Chromosome linked to cholesterol absorption Using strains of mice that only differ from each other on a small area of one chromosome researchers identify two sets of genes important for cholesterol absorption and excretion the balance of which is a key contributor to coronary heart disease susceptibility More Tags cholesterol coronary heart disease Jan L Breslow February 6 2006 Science News Genetic studies in mice yield clues to how heart disease is inherited Heart disease tends to run in families and scientists have long known that genetics play an important role Now new research in mice from the laboratory of Rockefeller s Jan L Breslow shows that the genetics of heart disease are more complicated than previously thought More Tags heart disease Jan L Breslow April 26 2004 Science News Newly discovered gene controls levels of bad cholesterol in mice Heart disease researchers at Rockefeller University have discovered the function of a gene associated with high cholesterol levels in humans Using mice as test subjects the Rockefeller scientists determined that the gene called Pcsk9 can decrease the number of receptors on liver cells that remove the bad LDL cholesterol from the blood More Tags cholesterol heart disease Jan L Breslow November 26 2003 Science News Genes may protect against heart disease rather than be harmful as previously thought A genetic pathway whose activity was suspected to advance heart disease by increasing inflammation in the blood vessels and arteries feeding the heart may actually protect against it at least in laboratory mice reports a team of Rockefeller University scientists led by Jan Breslow M D in the Nov 25 issue of Proceedings of the National Academy of Sciences More Tags heart disease Jan L Breslow June 25 2002 Science News Proteins that transport cholesterol identified Professor Jan Breslow and colleagues including biomedical fellow Raymond Soccio recently discovered a novel subfamily of the START domain lipid transfer proteins which are thought to shuttle lipids such as cholesterol within cells More Tags cholesterol Jan L Breslow StarD4 July 24 2001 Campus News Rockefeller Heart Disease Study Seeks Patients A new study at The Rockefeller University Hospital will assess the potential of a fatty acid found in fish to reduce heart attack risk The researchers are testing the hypothesis that a daily dose of the

    Original URL path: http://newswire.rockefeller.edu/tag/jan-l-breslow/ (2016-02-13)
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  • Paul Greengard | Newswire | Page 2
    amino acid suggests new research from the Rockefeller University laboratories of Mary Jeanne Kreek and Paul Greengard By tracking individual amino acids in a single protein in mice and noticing how they change when the mice are given access to cocaine scientists are beginning to understand how an individual s underlying genetics can reinforce his addictive behavior More Tags addiction Mary Jeanne Kreek Paul Greengard September 1 2006 Science News Phosphorylation of WAVE1 protein remodels neuronal connections In a paper that marks the 50th anniversary of Paul Greengard s first Nature publication Greengard Yong Kim and their colleagues show how an interaction of several proteins alters neurons scaffolding to regulate the size and density of dendritic spines in the brain More Tags Paul Greengard phosphorylation WAVE1 February 10 2006 Science News PLD1 protein is implicated in Alzheimer s brain damage Most current Alzheimer s drugs target molecules responsible for memory formation but don t address the root of the problem plaques that build amid brain cells causing them to weaken and die Rockefeller scientists now say that a protein called PLD1 is closely linked to the pathways through which these plaques develop and may be a target for new drugs that better treat Alzheimer s More Tags Alzheimer s disease Paul Greengard PLD1 January 5 2006 Science News Scientists linking gene with serotonin and depression offer insights to new treatments New research shows that a gene called p11 is closely related to serotonin transmission in the brain and may play a key role in determining a person s susceptibility to depression Reported today in the journal Science the researchers say their discovery could lead to new treatments for certain mental disorders More Tags depression Paul Greengard serotonin November 21 2003 Science News Mouse studies show brain s master molecule produces same behavior from three different psychostimulant drugs A mouse study reported in this week s Science magazine shows that three drugs each acting on a different chemical transmitter in the brain all produce the same schizophrenia like symptoms by acting on a single master molecule in the brain More Tags Paul Greengard schizophrenia September 30 2003 Science News Leukemia drug Gleevec slows accumulation of major component of senile plaques in cell studies and in guinea pigs Gleevec the breakthrough drug for treating chronic myologenous leukemia CML and gastrointestinal stromal tumors slowed the accumulation of the major protein component of senile plaques that characterize Alzheimer s disease in laboratory cultures of mouse brain cells and guinea pigs More Tags Gleevec Leukemia Notch Paul Greengard August 14 2002 Science News Pivotal Brain Processor Decreased in Schizophrenia New York NY August 14 2002 Levels of a pivotal signal processor in the brain are reduced significantly in people with schizophrenia a study by scientists at The Rockefeller University Weill Cornell Medical College and University of California at Irvine has found More Tags DARPP 32 Paul Greengard schizophrenia March 18 2002 Science News Researchers Pinpoint How Estrogen Prevents Alzheimer s Senile Plaques Estrogen prevents the

    Original URL path: http://newswire.rockefeller.edu/tag/paul-greengard/page/2/ (2016-02-13)
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  • Pearl Meister Greengard Prize to be awarded to pioneering RNA researcher Joan Steitz | Newswire
    exemplifies the spirit of the Pearl Meister Greengard Prize Any recognition that calls attention to women s accomplishments in science is important for the future participation of women says Dr Steitz I am deeply honored to be a recipient of the Greengard Prize Dr Steitz is Sterling Professor of Molecular Biophysics and Biochemistry at Yale University and an investigator at the Howard Hughes Medical Institute She is best known for discovering and defining the function of RNA protein complexes called small nuclear ribonucleoproteins snRNPs which occur only in the cells of higher organisms These cellular complexes play a key role in the splicing of pre messenger RNA the earliest product of DNA transcription Both DNA and pre messenger RNA typically contain numerous nonsense segments called introns Working in the nucleus snRNPs cut the introns from pre mRNA and splice together the resulting segments which together make up messenger RNA Dr Steitz s research may yield new insights into the diagnosis and treatment of lupus an autoimmune disease that develops when patients make antibodies against their own DNA snRNPs or ribosomes the body s protein making factories She and her colleagues are also studying other snRNPs involved in excising a rare divergent class of introns and still other snRNPs involved in pre ribosomal RNA processing Dr Steitz earned her B S in chemistry from Antioch College in 1963 She became the sole woman in a class of 10 to begin graduate studies in biochemistry and molecular biology at Harvard and the first female graduate student to work under Jim Watson s guidance after another male professor questioned her aspirations for a Ph D because she was a woman During postdoctoral studies at the Laboratory of Molecular Biology in Cambridge England she used early methods to determine RNA sequences where ribosomes initiate protein synthesis on bacterial mRNAs She was appointed assistant professor at Yale in 1970 where her laboratory has been dedicated to studying RNA structure and function In 1979 Dr Steitz and her colleagues described snRNPs the building blocks of the spliceosome Her laboratory has defined the structures and functions of other noncoding ribonucleoproteins including several produced by transforming herpesviruses She has received numerous accolades for her work including the Albany Medical Center Prize in Medicine and Biomedical Research the Gairdner Foundation International Award the UNESCO L Oreal Award for Women in Science and the Rosalind E Franklin Award for Women in Science She is a member of the National Academy of Sciences and the Institute of Medicine and she received the National Medal of Science in 1986 Since 2007 she has served as a member of the Rockefeller University s Committee on Scientific Affairs a committee that advises the President and the Board of Trustees on all scientific matters Dr Steitz was chosen as the 2012 recipient of the Pearl Meister Greengard Prize by the selection committee of ten jurors of which five are Nobel Laureates The members of the selection committee included Marc Tessier Lavigne president of Rockefeller University

    Original URL path: http://newswire.rockefeller.edu/2012/09/10/pearl-meister-greengard-prize-to-be-awarded-to-pioneering-rna-researcher-joan-steitz/ (2016-02-13)
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