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  • Huilin Li | Newswire
    DNA helix and creates two duplicate helices was unknown After taking the first complete pictures of it researchers were surprised to find the complex possesses a counterintuitive architecture raising new questions about its functions More Tags Brain Chait chemical and structural biology DNA replication epigenetics Huilin Li Laboratory of DNA Replication Michael O Donnell replisome Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive

    Original URL path: http://newswire.rockefeller.edu/tag/huilin-li/ (2016-02-13)
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  • Laboratory of DNA Replication | Newswire
    DNA helix and creates two duplicate helices was unknown After taking the first complete pictures of it researchers were surprised to find the complex possesses a counterintuitive architecture raising new questions about its functions More Tags Brain Chait chemical and structural biology DNA replication epigenetics Huilin Li Laboratory of DNA Replication Michael O Donnell replisome February 9 2010 Science News Scientists crash test DNA s replication machinery Important molecular machines

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-dna-replication/ (2016-02-13)
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  • Michael O’Donnell | Newswire
    the first complete pictures of it researchers were surprised to find the complex possesses a counterintuitive architecture raising new questions about its functions More Tags Brain Chait chemical and structural biology DNA replication epigenetics Huilin Li Laboratory of DNA Replication Michael O Donnell replisome July 23 2014 Science News Researchers create the first model of the DNA replication fork This new tool promises to allow scientists to explore the as yet unknown details of how cells unzip the double stranded DNA molecule and replicate it a process crucial to life More Tags DNA replication epigenetics Michael O Donnell replication fork April 26 2006 Awards and Honors Four Rockefeller scientists elected to the National Academy of Sciences Titia de Lange Charles D Gilbert Michael E O Donnell and Jeffrey V Ravetch all heads of laboratories at Rockefeller University have been elected to the U S National Academy of Sciences a private organization of scientists and engineers dedicated to the furtherance of science and its use for the general welfare More Tags Charles D Gilbert Jeffrey Ravetch Michael O Donnell Titia de Lange U S National Academy of Sciences September 19 2005 Science News Clearing jams in the copy machinery Bacteria and

    Original URL path: http://newswire.rockefeller.edu/tag/michael-odonnell/ (2016-02-13)
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  • replisome | Newswire
    replisome structural biology November 2 2015 Science News Study reveals the architecture of the molecular machine that copies DNA Until now the exact configuration of the replisome a block of proteins that unzips the DNA helix and creates two duplicate helices was unknown After taking the first complete pictures of it researchers were surprised to find the complex possesses a counterintuitive architecture raising new questions about its functions More Tags

    Original URL path: http://newswire.rockefeller.edu/tag/replisome/ (2016-02-13)
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  • Researchers examine how a face represents a whole person in the brain | Newswire
    a deep groove in the sides of the macaque brain act as a specialized system for processing faces A similar system has been found in the human brain although it is not yet clear how the respective networks align Both macaque and human brains also have separate patches that respond to bodies The conventional anatomical wisdom is that both species brains process faces and bodies independently However some studies of human perception suggest a more complex situation For instance one study found people s perception of the emotion shown by a face can be altered by body posture even when the viewers were told to disregard the body More than the sum of the parts In the study Fisher began by showing macaques still images that either displayed the face of a fellow macaque alone the body without a face or the entire animal Using high resolution brain activity scans captured with a method known as functional magnetic resonance imaging he recorded how each of the six macaque facial patches located in a part of the brain called the superior temporal sulcus STS responded This approach was intended to reveal if a patch reacted strictly to faces or to some degree to bodies as well or if a patch preferred a face and body together more than the sum of both presented separately The only known way to get what we call a superadditive response which exceeds those prompted by an individual face and body combined is if there is some kind of interaction between the facial and body information in the patch Fisher says This interaction is important because it suggests the brain is no longer just receiving information from the eyes but beginning to make sense of it Two of the four face patches one in particular showed

    Original URL path: http://newswire.rockefeller.edu/2015/10/28/researchers-examine-how-a-face-comes-to-represent-a-whole-person-in-the-brain/ (2016-02-13)
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  • Clark Fisher | Newswire
    Tags Clark Fisher face patches facial processing Laboratory of Neural Systems Winrich Freiwald January 8 2015 Science News Facial motion activates a dedicated network within the brain research shows Like humans rhesus macaque monkeys have a network of small tareas within their brains that respond to images of faces New research shows these so called face patches also respond selectively to changing expressions and other facial motion More Tags Clark

    Original URL path: http://newswire.rockefeller.edu/tag/clark-fisher/ (2016-02-13)
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  • facial processing | Newswire
    it can represent the complete individual A new brain imaging study shows that parts of a primate face processing system actually prefer faces with bodies offering new insight into how faces convey this broader social information More Tags Clark Fisher face patches facial processing Laboratory of Neural Systems Winrich Freiwald Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011

    Original URL path: http://newswire.rockefeller.edu/tag/facial-processing/ (2016-02-13)
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  • Discovery of genes involved in inner ear development hints at a way to restore hearing and balance | Newswire
    time of birth Hair cells arising This cross section of the lining of the utricle shows hair cells red with blue nuclei that can arise from the dense layer of supporting cells directly below blue only when these proliferate Growing outward This perpendicular cross section of a mouse utricle in its early stages of development shows the expression of Sox11 red one of the proteins identified in the study at the organ s periphery just outside the region containing hair cells green A closer look The second protein Sox4 magenta appears at the outer edge of the developing utricle and occasionally within the nuclei of new hair cells green Proliferating support cells which in some cases become hair cells appear in white Cochlear spiral Hair cells within the organ of Corti which is located within the cochlea above of a mouse s inner ear respond to sound waves by producing an electrical signal that travels to the brain These hair cells are developmentally identical to those responsible for the sense of balance Defects throughout Mice that did not produce Sox11 and Sox4 had malformed inner ear structures as shown by the lining or sensory epithelium green that contains hair cells For example in normal development left the cochlea circular structure on top and utricle circular structure immediately below are severely malformed in the absence of the proteins right Loss of hair cells In normal development left the hair cells purple that respond to sound form four neat rows in the organ of Corti which is located within the cochlea a spiral canal Without Sox11 and Sox4 right these hair cells fail to form Artificial induction To test if Sox11 and Sox4 could on their own induce the formation of hair cells Gnedeva infected fully developed utricles with a virus carrying

    Original URL path: http://newswire.rockefeller.edu/2015/10/26/discovery-of-genes-involved-in-inner-ear-development-hints-at-a-way-to-restore-hearing-and-balance/ (2016-02-13)
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