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  • A. James Hudspeth | Newswire
    the inner ear and how they contribute to hearing and hearing loss More Tags A James Hudspeth American Philosophical Society Laboratory of Sensory Neuroscience December 4 2009 Science News Elusive protein points to mechanism behind hearing loss A serendipitous discovery in zebra fish larvae born deaf has helped narrow down the function of an elusive protein necessary for hearing and balance In addition to unveiling a potential target for therapy the work suggests that hearing loss may arise from a faulty pathway that translates sound into electrical nerve impulses the brain can understand More Tags A James Hudspeth Laboratory of Sensory Neuroscience September 23 2008 Science News Neuron in zebrafish may reveal clues to the wiring of the human ear Neurobiology like networking is about making the right connections Now new research shows that developing neurons in zebrafish know exactly where to go to find the right match Because analogous cells exist in the human ear the work may ultimately lead to new therapies for people who are hard of hearing More Tags A James Hudspeth zebrafish March 25 2008 Grants and Gifts 4 5 million grant funds interdisciplinary fellowships at Rockefeller The grant from the Leon Levy Foundation will fund the Leon Levy Presidential Fellowships in Neuroscience designed to recruit young scientists whose research is at the crossroads of physics mathematics and neuroscience More Tags A James Hudspeth Cori Bargmann November 18 2005 Science News New report bolsters theory on ear s inner amplifier Two competing theories exist to explain how the human ear amplifies sound Now using ear hair cells from a bullfrog scientists at Rockefeller provide evidence to bolster the theory they proposed in 1998 More Tags A James Hudspeth cochlea stereocilia October 16 1995 Campus News Neuroscientist A James Hudspeth Joins Rockefeller Faculty An expert in

    Original URL path: http://newswire.rockefeller.edu/tag/a-james-hudspeth/ (2016-02-13)
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  • hearing | Newswire
    utricle June 7 2006 Science News Sound investment A new mathematical method provides a better way to analyze noise Even though the brain has only a small fraction of its sensory receptors dedicated to sound the human auditory system is lightning fast and researchers say that s because the brain can perform a series of intricate calculations that translate minimal input into maximal understanding In a potential breakthrough in sound

    Original URL path: http://newswire.rockefeller.edu/tag/hearing/ (2016-02-13)
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  • inner ear | Newswire
    scientists suggest More Tags A James Hudspeth hearing inner ear Ksenia Gnedeva Laboratory of Sensory Neuroscience sox11 sox4 soxC utricle October 27 2000 Science News Researchers Identify Molecule That Senses Osmotic Pressure in Vertebrates Researchers at the Howard Hughes Medical Institute and Rockefeller University have identified a molecule in vertebrates that senses osmotic pressure the measure of saltiness essential for living cells and may provide an inroad into understanding inner

    Original URL path: http://newswire.rockefeller.edu/tag/inner-ear/ (2016-02-13)
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  • Ksenia Gnedeva | Newswire
    to the production of delicate sensors called hair cells in mammals These genes or others in the same pathway could be promising targets for efforts to treat hearing loss or balance problems the scientists suggest More Tags A James Hudspeth hearing inner ear Ksenia Gnedeva Laboratory of Sensory Neuroscience sox11 sox4 soxC utricle Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014

    Original URL path: http://newswire.rockefeller.edu/tag/ksenia-gnedeva/ (2016-02-13)
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  • Laboratory of Sensory Neuroscience | Newswire
    this honorary society recognizes outstanding accomplishments within a member s field Hudspeth has worked toward a deepened understanding of the receptor cells of the inner ear and how they contribute to hearing and hearing loss More Tags A James Hudspeth American Philosophical Society Laboratory of Sensory Neuroscience December 4 2009 Science News Elusive protein points to mechanism behind hearing loss A serendipitous discovery in zebra fish larvae born deaf has

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-sensory-neuroscience/ (2016-02-13)
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  • sox4 | Newswire
    the production of delicate sensors called hair cells in mammals These genes or others in the same pathway could be promising targets for efforts to treat hearing loss or balance problems the scientists suggest More Tags A James Hudspeth hearing inner ear Ksenia Gnedeva Laboratory of Sensory Neuroscience sox11 sox4 soxC utricle Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013

    Original URL path: http://newswire.rockefeller.edu/tag/sox4/ (2016-02-13)
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  • Researchers explore how a cell’s protein-making factories are assembled | Newswire
    as a scaffold for protein synthesis Following ribosome assembly all ribosomes must have the same composition with four ribosomal RNAs and all ribosomal proteins in their appropriate positions says the study s senior author Sebastian Klinge assistant professor and head of the Laboratory of Protein and Nucleic Acid Chemistry We wanted to understand how four ribosomal RNAs and 79 different proteins are assembled to make a functional ribosome that later is able to produce all cellular proteins In the study the researchers focused on the early phases of the process that takes place inside the nucleolus a structure inside the cell s nucleus where ribosomal RNA precursors are made This part of ribosome assembly has previously been hard to study because it happens continuously while the RNA precursors are being transcribed from DNA Ribosomes are composed of two subunits one small and one large this study focused on the assembly of the small subunit which happens first Sebastian Klinge and Malik Chaker Margot the study s first author engineered yeast cells to generate ribosomal RNA molecules of varying lengths which represented different steps in the assembly process Each of these RNAs contained an extra element that acted as biochemical bait and using this bait the researchers were able to isolate proteins that specifically bind to the RNA We chose six transcriptional stages and using the bait system we isolated all the proteins and RNA complexes associated with those transcriptional stages says Chaker Margot With this method the researchers were able to compile a list of pre ribosomal components and note at which stages each is present within the precursor to the small ribosomal subunit The researchers say their findings will provide a better understanding of how ribosomes are put together a process fundamental to all living cells In addition a

    Original URL path: http://newswire.rockefeller.edu/2015/10/23/researchers-explore-how-a-cells-protein-making-factories-are-assembled/ (2016-02-13)
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  • Laboratory of Protein and Nucleic Acid Chemistry | Newswire
    process that happens continuously inside cells are not yet fully understood Using a new technique they devised researchers have mapped out the proteins involved in the early stages of the construction of a ribosome More Tags chemical and structural biology Laboratory of Protein and Nucleic Acid Chemistry Malik Chaker Margot ribosome sebastian klinge small ribosomal subunit Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-protein-and-nucleic-acid-chemistry/ (2016-02-13)
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