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  • New faculty member develops light-based tools to study the brain | Newswire
    research specialist I have always been most fascinated by fundamental questions that was the reason I studied physics and went into quantum mechanics In the early part of my career I was looking for new challenges and I realized that understanding the brain represented something fundamental and challenging yet also tangible Vaziri says I hoped that as a physicist I could contribute new conceptual ideas and bring in techniques to address key limitations in our understanding of brain function Innovative imaging approaches While on the faculty at the University of Vienna and the Research Institute for Molecular Pathology IMP his most recent position Vaziri put his background to use developing new ways to peer into the brain One of these called wide field two photon light sculpting makes it possible to simultaneously record many individual signals produced by densely packed neurons Light sculpting employs a femtosecond pulsed laser source whose spectrum is dispersed then brought back into register to generate a disk of light that illuminates many neurons only within a single plane but not those above or below In addition to observing the neurons the researchers can activate them using optogenetics a method that employs light to activate or inhibit genetically altered neurons The Vaziri lab has developed variations on this approach that allow for single cell resolution activation of neurons in specific spatiotemporal patterns Vaziri and his colleagues have also developed a second technique light field deconvolution microscopy which uses views formed by an array of micron sized lenses to generate a three dimensional representation of neural activity at high speed across an even larger area up to the entire brain of small organisms Using this technique the researchers could capture the neuronal activity within a roundworm s full 302 neuron brain during free behavior as well capture

    Original URL path: http://newswire.rockefeller.edu/2015/10/15/new-faculty-member-develops-light-based-tools-to-study-the-brain/ (2016-02-13)
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  • Alipasha Vaziri | Newswire
    track associate professor in September seeks to capture and manipulate interactions among neurons within the living brain He uses his background in physics to develop innovative ways of recording neural activity quickly and across large areas all at single cell resolution More Tags Alipasha Vaziri new faculty Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011 more About Contact

    Original URL path: http://newswire.rockefeller.edu/tag/alipasha-vaziri/ (2016-02-13)
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  • Two Rockefeller postdocs recognized by Blavatnik Regional Awards | Newswire
    finalists are awarded 10 000 each and will be honored at the Academy s annual gala in November Hani Goodarzi top Ziv Shulman Numerous other Rockefeller researchers including most recently postdoc Stephen Brohawn have previously been selected as finalists or winners of the Regional Awards The foundation and the academy also recognize faculty level scientists through a National Award Luciano Marraffini an assistant professor and head of the Laboratory of Bacteriology was selected as a finalist for the Blavatnik National Award earlier this year Hani Goodarzi Goodarzi works in the Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology headed by Sohail Tavazoie the Leon Hess Associate Professor and Senior Attending Physician at Rockefeller University Hospital Drawing on his background in computational and experimental biology Goodarzi s research combines the analysis of large data sets with rigorous cellular molecular and biochemical experimentation to develop new frameworks to study cancer progression Using an algorithm he developed while a Ph D student at Princeton University he has scanned both the sequence and shape of RNA molecules in breast cancer cells leading to the discovery of a post transcriptional network that regulates metastasis Ziv Shulman Shulman worked in the Laboratory of Molecular Immunology headed by Michel Nussenzweig the Zanvil A Cohn and Ralph M Steinman Professor a Howard Hughes Medical Institute Investigator and Senior Physician at the Rockefeller University Hospital Shulman s research focuses on the formation of protective antibodies during the immune response By directly visualizing this process he uncovered the cellular mechanisms and signaling events by which the immune system in response to vaccination selects cells to produce efficient antibodies against future invading pathogens His work helped answer several questions in the field and has implications for the design of vaccination strategies especially those that induce immune protection against chronic infections

    Original URL path: http://newswire.rockefeller.edu/2015/10/13/two-rockefeller-postdocs-recognized-by-blavatnik-regional-awards/ (2016-02-13)
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  • Blavatnik Awards | Newswire
    Award for Young Scientists Fisher is a postdoc in James Hudspeth s Laboratory of Sensory Neuroscience studying the biophysics and neurophysiology of the auditory system He is one of seven winners of the prize which is given to faculty and postdocs in the tri state area More Tags Blavatnik Awards May 23 2012 Awards and Honors Two Rockefeller postdocs win Blavatnik Awards Two Rockefeller University postdoctoral fellows have been named winners in the 2012 Blavatnik Awards for Young Scientists competition from The New York Academy of Sciences Andrey Feklistov from Seth Darst s Laboratory of Molecular Biophysics and Nicholas Stavropoulos from Michael Young s Laboratory of Genetics are among 9 winners and 2 finalists The awards are given to researchers under the age of 42 who demonstrate highly innovative impactful and interdisciplinary accomplishments in the life sciences physical sciences mathematics and engineering More Tags Blavatnik Awards July 2 2010 Awards and Honors Rockefeller postdoc named finalist for Blavatnik Awards for Young Scientists Agnel Sfeir a postdoctoral fellow in Titia de Lange s Laboratory of Cell Biology and Genetics has been named a finalist in the fourth annual Blavatnik Awards for Young Scientists competition which recognizes the contributions of young scientists and engineers in New York New Jersey and Connecticut More Tags Agnel Sfeir Blavatnik Awards Laboratory of Neurogenetics and Behavior Leslie B Vosshall Titia de Lange November 17 2009 Awards and Honors Shaham and Chalasani named winners of 2009 Blavatnik Awards Associate Professor Shai Shaham and Postdoctoral Fellow Sreekanth H Chalasani who were named finalists in the third annual competition in September were honored last night with six other winners at the New York Academy of Sciences Science and the City Gala More Tags Blavatnik Awards Cori Bargmann Laboratory of Developmental Genetics Laboratory of Neural Circuits and Behavior Shai Shaham

    Original URL path: http://newswire.rockefeller.edu/tag/blavatnik-awards/ (2016-02-13)
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  • Blavatnik Awards for Young Scientists | Newswire
    New Jersey and Connecticut Goodarzi is a postdoc in Sohail Tavazoie s lab Shulman a former postdoc in Michel Nussenzweig s lab has since established his own lab at the Weizmann Institute of Science in Israel More Tags Blavatnik Awards Blavatnik Awards for Young Scientists Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology Hani Goodarzi Laboratory of Molecular Immunology Michel C Nussenzweig Michel Nussenzweig Sohail Tavazoie Ziv Shulman Search

    Original URL path: http://newswire.rockefeller.edu/tag/blavatnik-awards-for-young-scientists/ (2016-02-13)
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  • Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology | Newswire
    Goodarzi Laboratory of Molecular Immunology Michel C Nussenzweig Michel Nussenzweig Sohail Tavazoie Ziv Shulman May 7 2015 Science News Fragments of tRNA suggest a novel mechanism for cancer progression Researchers discover that particular genetic fragments of a type of RNA known as transfer RNA or tRNA appear to be capable of reducing the growth and spread of breast cancer cells More Tags breast cancer cancer Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology metastasis Sohail Tavazoie tRNA January 26 2015 Science News Research implicates metabolic process of the liver in the spread of colorectal cancer By identifying genes that become activated in cancer cells that successfully metastasize to the liver researchers at Rockefeller have implicated metabolic processes within the liver as a possible means by which starving transient cancer cells can go on to form deadly new colonies More Tags cancer Colorectal cancer Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology metastasis microRNA Sohail Tavazoie January 16 2015 Campus News Cancer biologist and physician Sohail Tavazoie is promoted to associate professor Tavazoie who joined Rockefeller in 2009 works to understand how cancer cells become able to escape a tumor and invade other organs a process known as metastasis

    Original URL path: http://newswire.rockefeller.edu/tag/elizabeth-and-vincent-meyer-laboratory-of-systems-cancer-biology/ (2016-02-13)
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  • Hani Goodarzi | Newswire
    and Vincent Meyer Laboratory of Systems Cancer Biology Hani Goodarzi Laboratory of Molecular Immunology Michel C Nussenzweig Michel Nussenzweig Sohail Tavazoie Ziv Shulman June 15 2015 Awards and Honors First Winners of Tri Institutional Breakout Awards Announced Six young scientists at Memorial Sloan Kettering Cancer Center Rockefeller University and Weill Cornell Medical College have been named the inaugural winners of a new prize for postdoctoral investigators in the life sciences

    Original URL path: http://newswire.rockefeller.edu/tag/hani-goodarzi/ (2016-02-13)
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  • Laboratory of Molecular Immunology | Newswire
    favor the selection of B cells capable of producing antibodies finely tuned to target that invader More Tags affinity maturation Alex Gitlin antibodies B cell selection germinal centers immune response Laboratory of Molecular Immunology Michel Nussenzweig June 18 2015 Science News Sequential immunizations could be the key to HIV vaccine Scientists have thought for some time that multiple immunizations each tailored to specific stages of the immune response could be used to generate a special class of HIV fighting antibodies so called broadly neutralizing antibodies These findings provide the first evidence supporting this approach More Tags antigen broadly neutralizing antibodies HIV vaccine immune response Laboratory of Molecular Immunology Lotta von Boehmer Michel Nussenzweig Pia Dosenovic January 30 2015 Science News Latent HIV may lurk in quiet immune cells research suggests When researchers sequenced and compared sites where the virus had integrated into the genomes of infected CD4 T cells they found evidence dormant but dangerous HIV was hiding out in cells that had never been copied not the more abundant cloned cells More Tags CD4 T cell clonal expansion Laboratory of Molecular Immunology latent HIV Lillian Cohn Michel Nussenzweig viral integration September 23 2014 Science News Imaging studies open a window on how effective antibodies are formed By imaging the immune response researchers have observed how two types of immune cells interact with one another during a critical period following infection in order to prepare the best antibodies and establish long lasting protection More Tags antibodies B cells fluorescent microscopy germinal center immunology Laboratory of Molecular Immunology Michel C Nussenzweig t cells September 30 2010 Science News Research on killer HIV antibodies provides promising new ideas for vaccine design By detailing the molecular workings of broadly neutralizing anti HIV antibodies found in so called slow progressing HIV patients researchers hope

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-molecular-immunology/ (2016-02-13)
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