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  • melanoma | Newswire
    News Drug is identified that could block the spread of melanoma Researchers have found a promising new route to slowing or even preventing melanoma cells from spreading within the body Using a compound that targets a hormone receptor the team found they could reduce tumors recruitment of blood vessels a process necessary for metastasis More Tags cancer melanoma metastasis Sohail Tavazoie July 18 2007 Grants and Gifts Gift from Milstein

    Original URL path: http://newswire.rockefeller.edu/tag/melanoma/ (2016-02-13)
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  • metastasis | Newswire
    on to form deadly new colonies More Tags cancer Colorectal cancer Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology metastasis microRNA Sohail Tavazoie January 16 2015 Campus News Cancer biologist and physician Sohail Tavazoie is promoted to associate professor Tavazoie who joined Rockefeller in 2009 works to understand how cancer cells become able to escape a tumor and invade other organs a process known as metastasis He searches for genes and molecular pathways cancer cells exploit in order to metastasize and with that knowledge hopes to develop future treatments to prevent or interfere with the process More Tags associate professor breast cancer cancer colon cancer Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology endothelial cells melanoma metastasis microRNA promotion RNA Sohail Tavazoie July 28 2014 Science News Discovery of pro metastasis protein reveals mysterious link to neurodegeneration Mice injected with metastatic breast cancer cells showed less metastasis when researchers silenced the protein TARBP2 in these cells TARBP2 appears to promote metastasis in part by blocking suppressor genes including two linked with neurodegeneration More Tags cancer metastasis neurodegeneration RNA Sohail Tavazoie TARBP2 April 2 2014 Science News Drug is identified that could block the spread of melanoma Researchers have found a promising new route to slowing or even preventing melanoma cells from spreading within the body Using a compound that targets a hormone receptor the team found they could reduce tumors recruitment of blood vessels a process necessary for metastasis More Tags cancer melanoma metastasis Sohail Tavazoie December 16 2011 Science News In cancer molecular signals that recruit blood vessels also trigger metastasis Cancer cells are most deadly when they re on the move able not only to destroy whatever organ they are first formed in but also to create colonies elsewhere in the body New research has now

    Original URL path: http://newswire.rockefeller.edu/tag/metastasis/ (2016-02-13)
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  • microRNA | Newswire
    for development health and disease including cancer More Tags cancer Claudio Alarcón Laboratory of Systems Cancer Biology m6A METTL3 microRNA RNA Sohail Tavazoie March 12 2015 Science News Study details microRNA s role as a double agent during Hep C infection Both the virus and liver cells need the microRNA molecules the liver produces to regulate its genes Researchers found that by co opting one microRNA the virus may cause changes in gene expression in liver cells More Tags Charles Rice hepatitis C Joseph Luna Laboratory of Molecular Neuro oncology Laboratory of Virology and Infectious Disease liver cancer microRNA miRNA 122 robert darnell January 26 2015 Science News Research implicates metabolic process of the liver in the spread of colorectal cancer By identifying genes that become activated in cancer cells that successfully metastasize to the liver researchers at Rockefeller have implicated metabolic processes within the liver as a possible means by which starving transient cancer cells can go on to form deadly new colonies More Tags cancer Colorectal cancer Elizabeth and Vincent Meyer Laboratory of Systems Cancer Biology metastasis microRNA Sohail Tavazoie January 16 2015 Campus News Cancer biologist and physician Sohail Tavazoie is promoted to associate professor Tavazoie who

    Original URL path: http://newswire.rockefeller.edu/tag/microrna/ (2016-02-13)
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  • RNA | Newswire
    metastasis neurodegeneration RNA Sohail Tavazoie TARBP2 November 28 2012 Campus News Robert Darnell named president of New York Genome Center Darnell will direct all aspects of the NYGC including its scientific and research activities and the recruitment and development of a world class scientific team in genomic research and medicine Founded in 2010 the NYGC will be one of the largest genomics research facilities in North America integrating sequencing bioinformatics and data management More Tags genomics Laboratory of Molecular Neuro oncology RNA Robert B Darnell August 7 2009 Science News Model suggests how life s code emerged from primordial soup It would seem a stunning improbability for a whirlwind to spin through a junkyard and leave behind a fully assembled jumbo jet This colorful metaphor by astronomer Fred Hoyle points out the difficulties encountered by scientists when they try to understand how life could have emerged billions of years ago Researchers at Rockefeller University now show how crude pieces of a genetic system could self assemble and generate the rules of life s most fundamental code More Tags Amino acids Building blocks Life RNA July 24 2009 Campus News Tenure awarded to RNA researcher Thomas Tuschl The university promotes a biochemist who researches RNA interference RNAi the process by which small RNA molecules interfere with gene expression More Tags RNA Thomas Tuschl November 2 2008 Science News New method provides panoramic view of protein RNA interactions in living cells The postgenomic era has taught us a big one That the measure of human complexity has less to do with how many genes we have as it does with how we process them Now Rockefeller University scientists offer for the first time a genome wide view from the first chromosome to the last of how differences in RNA can explain how

    Original URL path: http://newswire.rockefeller.edu/tag/rna/ (2016-02-13)
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  • Physician scientist, interested in obesity-related disease, to join faculty | Newswire
    physician scientist who wants to do fundamental research on the mechanisms underlying human disease I am looking forward to taking advantage of the amazing opportunities for collaboration with my new colleagues Cohen earned his M D from Weill Cornell Medical College through the Tri Institutional M D Ph D Program and went on to specialize in preventive cardiology He developed a clinical focus on the cardiovascular complications associated with obesity and was impressed by the wide variation in the degree of disease obese patients experience In order to begin to explain why Cohen and others first had to take a close look at the different types of fat White fat cells warehouse fat in large droplets attracting inflammation and causing disease fat stored within the abdomen or visceral fat contains white cells But fat can also have healthful effects Found in infants and recently in small amounts in adults brown fat cells evolved to maintain body temperature by burning the fat they store Scientists have more recently found small deposits of a third type beige fat Located in clusters and surrounded by white cells beige cells can burn calories just like brown fat cells when exposed to cold or to certain hormones Beige fat cells are generally found subcutaneously or in deposits under the skin Cohen s postdoctoral research helped establish the health protecting effect of beige fat and identified a key role for the molecule PRMD16 in activating beige fat cells so they burn calories just like brown cells When looking at subcutaneous fat the less detrimental type of deposit that contains beige cells Cohen and his colleagues found significant levels of PRMD16 which was already known to help regulate the expression of RNA the molecule that carries protein making instructions for DNA They then genetically modified mice so

    Original URL path: http://newswire.rockefeller.edu/2015/01/09/physician-scientist-interested-in-obesity-related-disease-to-join-faculty/ (2016-02-13)
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  • beige fat | Newswire
    cardiologist is returning to Rockefeller where he did his graduate work In his new lab Cohen will study the molecular origins of obesity related metabolic disease with the goal of developing treatments More Tags beige fat faculty search Laboratory of Molecular Metabolism Obesity Paul Cohen prmd16 Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011 more About Contact Follow

    Original URL path: http://newswire.rockefeller.edu/tag/beige-fat/ (2016-02-13)
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  • faculty search | Newswire
    origins of obesity related metabolic disease with the goal of developing treatments More Tags beige fat faculty search Laboratory of Molecular Metabolism Obesity Paul Cohen prmd16 November 10 2005 Science News Application deadline for faculty search is next week Scientists interested in tenure track faculty positions in the biological and biomedical sciences at The Rockefeller University must submit applications by Nov 15 More Tags faculty search Search for Categories Science

    Original URL path: http://newswire.rockefeller.edu/tag/faculty-search/ (2016-02-13)
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  • Laboratory of Molecular Metabolism | Newswire
    and cardiologist is returning to Rockefeller where he did his graduate work In his new lab Cohen will study the molecular origins of obesity related metabolic disease with the goal of developing treatments More Tags beige fat faculty search Laboratory of Molecular Metabolism Obesity Paul Cohen prmd16 Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014 2013 2012 2011 more About Contact

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-molecular-metabolism/ (2016-02-13)
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