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  • Charles Rice | Newswire
    infectious disease research It recognizes Rice s work on understanding the lifecycle of the hepatitis C virus and laying the groundwork for effective therapeutic developments More Tags awards Charles Rice hepatitis C virus infectious disease Laboratory of Virology and Infectious Disease Robert Koch Award March 12 2015 Science News Study details microRNA s role as a double agent during Hep C infection Both the virus and liver cells need the

    Original URL path: http://newswire.rockefeller.edu/tag/charles-rice/ (2016-02-13)
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  • hepatitis C virus | Newswire
    most distinguished scientific prizes and honors extraordinary accomplishments in infectious disease research It recognizes Rice s work on understanding the lifecycle of the hepatitis C virus and laying the groundwork for effective therapeutic developments More Tags awards Charles Rice hepatitis C virus infectious disease Laboratory of Virology and Infectious Disease Robert Koch Award Search for Categories Science News Awards and Honors Campus News Grants Gifts Topics Video Archive 2015 2014

    Original URL path: http://newswire.rockefeller.edu/tag/hepatitis-c-virus/ (2016-02-13)
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  • infectious disease | Newswire
    patient s blood The work reported this week in Nature brings fresh optimism to the field of HIV immunotherapy and suggests new strategies for fighting or even preventing HIV infection More Tags AIDS broadly neutralizing antibodies clinical trial HIV infectious disease Michel C Nussenzweig March 26 2015 Science News Genetic mutation helps explain why in rare cases flu can kill A small number of children who catch the influenza virus fall so ill they end up in the hospital even while their family and friends recover easily New research from Rockefeller helps explain why a rare genetic mutation that prevents the production of a critical protein interferon that is needed to fight off the virus More Tags infectious disease influenza interferon Jean Laurent Casanova St Giles Laboratory of Human Genetics of Infectious Diseases December 9 2014 Grants and Gifts Rockefeller University Hospital shares 2 8 million contract to study preventing drug resistant infections in the community The Community Acquired MRSA Project CAMP2 will enroll patients with skin infections provide English and Spanish language health education materials about community acquired drug resistant staph infections and incorporate a home visit program by community health workers to evaluate the effectiveness of household decontamination

    Original URL path: http://newswire.rockefeller.edu/tag/infectious-disease/ (2016-02-13)
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  • Laboratory of Virology and Infectious Disease | Newswire
    liver cancer microRNA miRNA 122 robert darnell February 12 2015 Science News Key to blocking influenza virus may lie in a cell s own machinery Researchers have found that the immune system fights a flu infection by turning off cellular enzymes the virus needs to put the final touches on new viral particles The unfinished particles cannot spread infection to new cells More Tags Charles M Rice immune response interferon Jean Laurent Casanova Laboratory of Virology and Infectious Disease Meike Dittmann PAI 1 Paul Bieniasz seasonal flu viral replication April 10 2011 Science News Big picture of how interferon induced genes launch antiviral defenses revealed A team of researchers led by scientists from Rockefeller University for the first time has carried out a comprehensive systematic evaluation of the antiviral activity of factors induced by interferon The findings published online today in the journal Nature are a first step toward unraveling how these naturally occurring molecules work to inhibit viruses More Tags Aaron Diamond AIDS Research Center John Schoggins Laboratory of Virology and Infectious Disease Paul Bieniasz June 8 2010 Science News Researchers modify yellow fever vaccine to fight malaria A genetically modified vaccine originally used to eradicate yellow fever could be the key to stopping a mosquito borne scourge that afflicts much of the developing world More Tags Charles M Rice Laboratory of Molecular Immunology Laboratory of Virology and Infectious Disease malaria Michel C Nussenzweig yellow fever YF17D CSP December 23 2009 Science News Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate In a series of three snapshots that recapitulate the coordinated actions scientists reveal how a protein essential for the replication of the hepatitis C virus moves along its nucleic acid substrate The finding illustrates the nucleotide dependent changes of interactions between

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-virology-and-infectious-disease/ (2016-02-13)
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  • The Rockefeller University designated a “Milestones in Microbiology” site by the American Society for Microbiology | Newswire
    Gotschlich The dedication ceremony will feature remarks by Marc Tessier Lavigne Rockefeller University president as well as James Darnell Vincent Astor Professor Emeritus and Gotschlich R Gwin Follis Chevron Professor Emeritus who will speak on the university s role in early microbiology and on its history of meningitis research A plaque commemorating the Milestones in Microbiology designation to be installed in Rockefeller s Collaborative Research Center will be presented by Stanley Maloy past president of the ASM Rockefeller University has served as an intellectual hub for microbiology supporting innovative research on microbes that has provided both fundamental insights into science and practical applications that have impacted the world says Maloy The steady stream of influential scientists who have passed through its laboratories have made important discoveries in every area of medical microbiology from early work demonstrating that heredity is determined by DNA the growth of mammalian cells in tissue culture the nature of blood groups insights into immunity and the development of antibiotics and vaccines through recent discoveries on viruses bacteria parasites and host responses Microbiology was the cornerstone of Rockefeller s mission at our founding and it remains a vibrant field of study in our laboratories today says Tessier Lavigne Today s generation of Rockefeller microbiologists immunologists and cell biologists are building on their predecessors twelve decades of work driving discoveries that will lead to new treatments and cures for infectious disease We are enormously proud of Rockefeller s legacy in this field and on behalf of our scientific community I am greatly honored by this recognition from the ASM Previously designated Milestones in Microbiology sites include the Waksman Laboratory at Rutgers University Hopkins Marine Station in Monterey California the site of the University of Pennsylvania Laboratory of Hygiene Scripps Institution of Oceanography the Tulane University School of Public

    Original URL path: http://newswire.rockefeller.edu/2015/04/06/the-rockefeller-university-designated-a-milestones-in-microbiology-site-by-the-american-society-for-microbiology/ (2016-02-13)
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  • Research identifies a protein that helps determine the fate of RNA | Newswire
    turn down the activity of genes However Tavazoie says a lingering question remained What reads this chemical tag within the nucleus of cells Claudio Alarcón a research associate in my lab has identified one such reader protein Because of the fundamental nature of the processes involved this discovery has implications for cells normal function and for disease The tag called m6A is a methyl group attached to a particular part of an adenosine a component of RNA s sequence In previous work Alarcón and colleagues identified the m6A tag as an important regulator of the production of microRNAs The writer protein that places this tag was already known to mark RNA molecules that need to be spliced before they are translated into proteins Many genes contain sections that must be cut out and the RNA splicing process is crucial to the function and identity of a cell The recent experiments show that the newly discovered reader a protein known as HNRNPA2B1 recognizes m6A tags on RNA destined for two separate fates Trimming to become microRNAs or splicing for proper production into protein After recognizing m6A tags on microRNA precursors HNRNPA2B1 then recruits the cutting machinery responsible for further trimming and processing those RNA molecules Future work is required to understand how HNRNPA2B1 interacts with the proteins involved in the splicing of RNA The researchers suspected that the HNRNPA2B1 protein acts as a reader because they found it frequently binds to the same sites on the RNA molecule where the m6A tag attaches To determine what the alleged reader was doing there the team reduced its presence in cells In cells with reduced HNRNPA2B1 levels they found a shift in the expression of microRNAs overall with many microRNAs reduced They also looked at the effects on RNA destined for splicing Here

    Original URL path: http://newswire.rockefeller.edu/2015/08/27/research-identifies-a-protein-that-helps-determine-the-fate-of-rna/ (2016-02-13)
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  • Claudio Alarcón | Newswire
    More Tags Claudio Alarcón genetics and genomics Laboratory of Systems Cancer Biology m6A microRNA RNA splicing Sohail Tavazoie March 24 2015 Science News Chemical tag marks future microRNAs for processing study shows New research reveals how cells sort out the RNA molecules destined to become gene regulating microRNAs by tagging them Because microRNAs help control processes throughout the body this discovery has wide ranging implications for development health and disease

    Original URL path: http://newswire.rockefeller.edu/tag/claudio-alarcon/ (2016-02-13)
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  • Laboratory of Systems Cancer Biology | Newswire
    and disease More Tags Claudio Alarcón genetics and genomics Laboratory of Systems Cancer Biology m6A microRNA RNA splicing Sohail Tavazoie March 24 2015 Science News Chemical tag marks future microRNAs for processing study shows New research reveals how cells sort out the RNA molecules destined to become gene regulating microRNAs by tagging them Because microRNAs help control processes throughout the body this discovery has wide ranging implications for development health

    Original URL path: http://newswire.rockefeller.edu/tag/laboratory-of-systems-cancer-biology/ (2016-02-13)
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