archive-edu.com » EDU » S » STANFORD.EDU

Total: 204

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".

  • characteristic starlike surface structure astron is Greek for star They are nonenveloped viruses whose genome is composed of positive sense single stranded RNA Although they are very similar to the viruses of the family Picornaviridae and Caliciviridae they have many important features that distinguish themselves Astroviruses have been isolated from humans as well as many other animal species In most species the astroviruses cause gastroenteritis however in ducklings astrovirus infection

    Original URL path: http://virus.stanford.edu/astro/intro.html (2016-02-13)
    Open archived version from archive


  • in the literature did not display the characteristic astrovirus surface features Appleton and Higgins had reported an outbreak of mild diarrhea and vomiting among infants in a maternity ward a few months earlier They found a virus in feces samples from these infants that had been shed in large numbers and that were small round 29 to 30 nm in diameter and without defining features By electron microscopy they could tell that these viruses differed from the previously identified Norwalk virus and rotavirus because of their different size and morphology but they could not be identified as any other virus Years later specific immunological reagents became available and they were identified as astroviruses Subsequently viral particles that were of similar size and had characteristic starlike surface features were associated with gastroenteritis in a wide variety of young mammals and birds including lambs calves deer piglets kittens mice puppies and turkey poults In addition astroviruses were shown to case a rapidly fatal hepatitis in ducklings Astrovirus then appears to cause infection in a species specific manner In 1981 Lee and Kurtz reported the isolation of human astrovirus in human embryonic kidney HEK cells followed by serial passage of these viruses in

    Original URL path: http://virus.stanford.edu/astro/historicalnotes.html (2016-02-13)
    Open archived version from archive


  • in cell culture However serotypes 6 and 7 have recently been identified in the UK in 1989 and 1991 1992 respectively bringing the total number of human serotypes up to seven Astrovirus serotypes 6 and 7 are rare only one case of serotype 6 infection and only two cases of serotype 7 infection have been reported and are indistinguishable from serotypes 1 to 5 by electron microscopy cultivated in CaCo

    Original URL path: http://virus.stanford.edu/astro/classification&taxonomy.html (2016-02-13)
    Open archived version from archive


  • human astroviruses types 1 to 7 The different types of human astrovirus refer to their different serotypes Usually only the first five serotypes are recognized and considered because serotypes 6 and 7 are extremely rare only one case of serotype

    Original URL path: http://virus.stanford.edu/astro/humanviruses.html (2016-02-13)
    Open archived version from archive


  • rotavirus gastroenteritis After an incubation period of 1 4 days watery diarrhea lasts for another 1 4 days or more and is accompanied by abdominal discomfort vomiting and constitutional symptoms Immunity probably lasts for years and most adults are resistant to experimental infection Less severe responses develop following subsequent exposure to one of the other serotypes Viral Diarrhea Astrovirus infection is also a major cause of viral diarrhea As in

    Original URL path: http://virus.stanford.edu/astro/humandiseases.html (2016-02-13)
    Open archived version from archive


  • by person to person contacts but also by fomites and contaminated food and water The person to person fecal oral mode of transmission is most often seen in nosocomial day care center and family outbreaks Reports of transmission via contaminated

    Original URL path: http://virus.stanford.edu/astro/transmission.html (2016-02-13)
    Open archived version from archive


  • of the villus The astrovirus virion is regarded as a foreign particle by the host s immune system and a cell mediated response occurs If a person becomes infected with one serotype but has previously been infected with another serotype

    Original URL path: http://virus.stanford.edu/astro/immuneresponse.html (2016-02-13)
    Open archived version from archive


  • human astrovirus is somewhat likely to develop gastroenteritis or diarrhea from the infection This most beneficial treatment for a child with gastroenteritis or diarrhea is to administer oral rehydration therapy

    Original URL path: http://virus.stanford.edu/astro/management&therapy.html (2016-02-13)
    Open archived version from archive