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  • News and Announcements Archive - Nano@Wayne - Division of Research
    Clinton Metropark Authority and Macomb County and it aims to attract scientists educators and students from national and international institutions to conduct innovative research focusing on urban water systems and the environment HEART s training and research activites will impact more than 4 million people along the Huron to Erie corridor a binational body of water shared by the United States and Canada connecting the upper and lower Great Lakes who will receive recreational economical and ecological benefits from the project In addition HEART will inform watershed managers and policymakers from a variety of urban freshwater environments The project will launch real time beach water monitoring at the field station facilities at Lake St Clair Metropark and Belle Isle The project is led by a Wayne State University research team that includes Carol Miller professor of civil and environmental engineering in our College of Engineering and director of all HEART field stations and Judy Westrick director of WSU s Lumigen Instrumentation Center and principal investigator on the project that will launch the field station to develop real time beach water testing Together with the HEART collaborators they will support current and future collaborative research programs as well as provide educational opportunities to students at Wayne State Macomb Community College and many others State Representative Anthony Forlini and Dan Wyant director of the Department of Environmental Quality were instrumental in having 100 000 allocated in the Michigan Department of Environmental Quality budget to set up the lab The National Science Foundation assisted with a 25 000 planning grant to develop a strategic plan for the field stations Ribbon Cutting Photo L to R Rebecca Franchock Huron Clinton Metropark Authority controller Anthony Forlini State Representative Jon Allan director of the Office of the Great Lakes Stephen Lanier Wayne State University vice president

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14324 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    Such seizures which occur in more than 10 000 U S pediatric epilepsy patients every year can cause permanent brain damage or even death if allowed to persist Published in JAMA the study http jama jamanetwork com article aspx articleid 1861799 Lorazepam vs Diazepam for Pediatric Status Epilepticus A Randomized Clinical Trial was designed to test earlier assertions by many clinicians that lorazepam was more effective at controlling pediatric seizures The study authors wrote Potential advantages proposed in some studies of lorazepam include improved effectiveness in terminating convulsions longer duration of action compared with diazepam and lower incidence of respiratory depression Specific pediatric data comparing diazepam with lorazepam suggest that lorazepam might be superior but they are limited to reports from single institutions or retrospective studies with small sample sizes thus limiting generalizability Based on data collected over four years at 11 different U S pediatric emergency departments the new study found that treatment with lorazepam among pediatric patients with convulsive status epilepticus did not result in improved efficacy or safety compared with diazepam That determination led the study authors to conclude These findings do not support the preferential use of lorazepam for this condition Dr Mahajan a nationally recognized researcher in pediatric emergency medicine and a Wayne State University School of Medicine pediatrics professor recently appointed chair of the American Academy of Pediatrics Executive Committee of the Section on Emergency Medicine said the JAMA study provides a compelling example of how effective research in pediatric medicine based on treatment of patients right in the clinical setting can play a major role in improving outcomes Steven E Lipshultz M D chair of pediatrics at Wayne State University and chief of pediatrics at Children s Hospital of Michigan said this recent breakthrough will undoubtedly result in better care for pediatric patients

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14306 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    available in Census data including social environment To further examine the links between objective and perceived physical and social residential environment and preterm delivery among African American women a Wayne State University School of Medicine researcher has secured a three year 173 556 Ruth L Kirschstein National Research Service Award from the Eunice Kennedy Shriver National Institute of Child Health Human Development of the National Institutes of Health The research project Residential Environment and Preterm Delivery among African American Women will use data collected from 1 411 metropolitan Detroit area women enrolled in a study shortly after they gave birth to a single infant at Providence Hospital in Southfield Mich from 2009 to 2012 Shawnita Sealy Jefferson Ph D M P H postdoctoral fellow in the Department of Family Medicine and Public Health Sciences will use the grant to examine measurement of subjective neighborhood constructs including the methodological properties of subjective assessments In addition she will determine the associations between perceived social and physical residential environment and prevalence of preterm delivery as well as examine the associations between objective physical environment and PTD using multilevel modeling For this research Sealy Jefferson will work with her mentor Dawn Misra Ph D professor of family medicine and public health sciences in Wayne State s School of Medicine as well as Theresa Osypuk Sc D associate professor at University of Minnesota George Galster Ph D Clarence Hilberry Professor of Urban Affairs at Wayne State and Jason Booza Ph D assistant professor of family medicine and public health sciences at Wayne State Our research will extend the current knowledge of neighborhood effects on preterm delivery in several critical ways said Sealy Jefferson We will compare objective and subjective measures of residential environment determine how objective neighborhood measures influence perceptions of neighborhoods and conduct research

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14270 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    create advanced materials with high yield strength fracture toughness and ductility Their efforts have led to the development of a portfolio of bainitic steels and austempered ductile irons exhibiting an excellent combination of mechanical currently only available in the form of highly alloyed and costly exotic steels Putatunda s research was initially funded by a grant from the National Science Foundation award number 0854962 and more recently received funding from the New Economy Initiative s NEI Technology Development Incubator Program aimed at accelerating feasibility studies necessary for licensing industry partnerships and start up opportunities The NEI funding opened the door to a license agreement and the birth of Detroit Materials Inc The company was founded by Pedro Guillen in his role as entrepreneur in residence for the Detroit Technology Exchange with direct financial and administrative support from Detroit Innovate a new venture fund based in southeast Michigan Guillen Chief Executive Officer of Detroit Materials specializes in corporate innovation strategy and new technology commercialization He has over 15 years of product development and innovation experience in automotive defense off highway and clean energy markets He has led engineering teams developing proof of concept technologies and demonstrator vehicles for the Department of Defense as well as founded two successful start ups I am excited about the launch of Detroit Materials and the many opportunities that this new company will have to advance industries utilizing high strength steel said Hilary Ratner Ph D vice president for research at Wayne State University We have begun to reap the benefits of the changes that we ve put in place in technology commercialization over the last several years and the translation of Dr Putatunda s research into the marketplace is just one example of the great things happening at Wayne State University About Wayne State University

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14245 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    effects and the ability to taste water had the most significant impact flies that could not taste water lived up to 43 longer than other flies The findings suggest that in fruit flies the loss of taste may cause physiological changes to help the body adapt to the perception that it s not getting adequate nutrients In the case of flies whose loss of water taste led to a longer life authors say the animals may attempt to compensate for a perceived water shortage by storing greater amounts of fat and subsequently using these fat stores to produce water internally Further studies are planned to better explore how and why bitter and sweet tastes affect aging This brings us further understanding about how sensory perception affects health It turns out that taste buds are doing more than we think says senior author of the University of Michigan led study Scott Pletcher Ph D associate professor in the Department of Molecular and Integrative Physiology and research associate professor at the Institute of Gerontology We know they re able to help us avoid or be attracted to certain foods but in fruit flies it appears that taste may also have a very profound effect on the physiological state and healthy aging Pletcher conducted the study with lead author Michael Waterson a Ph D graduate student in U M s Cellular and Molecular Biology Program Our world is shaped by our sensory abilities that help us navigate our surroundings and by dissecting how this affects aging we can lay the groundwork for new ideas to improve our health says senior author of the other study Joy Alcedo Ph D assistant professor in the Department of Biological Sciences at Wayne State University formerly of the Friedrich Miescher Institute for Biomedical Research in Switzerland Alcedo

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14211 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    technology commercialization arena Shallman will lead Wayne State s licensing efforts to help identify evaluate develop and execute potential new innovations For the past six years he was director of commercialization at William Beaumont Health System and prior to that was the life sciences sector development manager at the Michigan Economic Development Corporation where he managed life sciences initiatives for the State of Michigan s Technology Tri Corridor Investment program and worked across the state to develop startup and attraction programs in the life sciences Massey s combined 28 years of biomedical research and business experience in the academic pharmaceutical and biotech arenas will benefit Wayne State University s efforts to identify start up opportunities and facilitate efforts of WSU entrepreneurs to create companies that will license and develop WSU technology He will play an important role in interacting with other academic institutions regional and state economic development agencies and the venture community Before joining Wayne State he was managing director of MicroDose Life Sciences and its associated venture capital fund LifeLine Ventures Prior to MicroDose Massey was an assistant professor of anesthesiology and pharmacology at the University of Michigan before joining Pfizer where he was responsible for the scientific and operational aspects of several drug development programs We are excited to have John and Ken join our technology commercialization team said Hilary Ratner vice president for research at Wayne State Together they bring new synergy and skills to our technology commercialization team that will speed and expand our ability to translate important university scientific and technological expertise into the marketplace and contribute even more to the regional economic ecosystem Shallman received his B A in business administration from Grand Valley State University Massey received a B S in biology and chemistry from Eastern Michigan University and his Ph D

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14181 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    exerts a novel inhibitory activity on hyperglycemia and could be developed and used to aid in diabetes management Recently funded by the National Center for Complementary and Alternative Medicine of the National Institutes of Health this 2 1 million transitional study will provide insights into the novel inhibitory action of GSE on postprandial hyperglycemia and will also provide preclinical data in support of the biological effectiveness and safety of GSE and its components in potential prevention and treatment of type 2 diabetes It is hopeful that our research may eventually lead to the successful development of a safe targeted nutritional intervention to support diabetes prevention and treatment said Kequan Zhou Ph D assistant professor of food and nutrition science in the College of Liberal Arts and Sciences and lead investigator on the grant Our study will provide important pre clinical data regarding the anti diabetic mechanisms biological efficacy and safety of GSE that should facilitate eventual translation into future clinical studies to assess GSE and its components as a safe low cost and evidence based nutritional intervention for diabetes Type 2 diabetes is the most common form of diabetes With type 2 diabetes the body does not produce enough insulin or the cells ignore the insulin In addition some groups have a higher risk for developing type 2 diabetes including African Americans Latinos Native Americans Asian Americans Pacific Islanders and the elderly Type 2 diabetes is one of the major chronic diseases of modern societies said Gloria Heppner Ph D associate vice president for research at Wayne State University It threatens the health of a variety of populations with growing numbers of young people being diagnosed with the disease every day Dr Zhou s study offers great hope for a potential treatment that is natural and without harmful side effects

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14136 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    develop recurrent UTIs UTIs can be a significant health problem for kids because of the medical complications that often accompany them Such recurring infections can also cause significant discomfort for affected children along with frequent visits to emergency rooms which add to the already soaring cost of medical care More than 3 percent of all American children develop UTIs each year and their infections account for more than 1 million visits to pediatricians annually according to the U S Department of Health and Human Services This health problem affects tens of millions of kids each year and up until now there has been no study like this to show convincingly that treating children who have both UTIs and VUR with long term low dose antibiotics reduces their risk of infections significantly said Mattoo There has been a great deal of debate on that question during the past ten to fifteen years but this new study should end that debate The data in the study are compellingly clear and will help clinicians achieve appropriate management and counseling of children after their first urinary tract infection Mattoo is an internationally recognized researcher in the field of pediatric kidney disease He pointed out that the prospective randomized placebo controlled study Antimicrobial Prophylaxis for Children with Vesicoureteral Reflux looked at 607 children with vesicoureteral reflux diagnosed after UTI between 2007 and 2011 The study found that the children who received long term antibiotics developed 50 fewer UTIs than the children in the control group who did not receive the antibiotic therapy I think the implications of the study send a very hopeful message to all of us who have struggled so hard in recent years to determine just how effective antibiotic prophylaxis is in protecting children with VUR from recurrent urinary tract infections and

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=14119 (2016-02-13)
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