archive-edu.com » EDU » W » WAYNE.EDU

Total: 427

Choose link from "Titles, links and description words view":

Or switch to "Titles and links view".
  • News and Announcements Archive - Nano@Wayne - Division of Research
    with genes that might contribute to this racial ethnic disparity in prostate cancer risk and progression They will look at MicroRNAs miRNAs small RNA molecules that play a role in both gene regulation and expression that are detectable in circulating blood as well as tissues as potential biomarkers for prostate cancer and tumor aggressiveness as well as prognosis Little is known about the role of miRNAs and their biogenesis in prostate cancer said Cathryn Bock Ph D associate professor of oncology at Wayne State University In addition less is understood about the possible race specific role of miRNAs in prostate cancer aggressiveness and outcomes Our research will look at polymorphisms in genes in the miRNA biogenesis pathway and plasma miRNA levels to see if they are potential indicators for prostate cancer aggressiveness or outcome and how these associations might link to race Bock and her collaborators will exam the association of inherited polymorphisms in genes in the miRNA biogenesis pathway as well as the association of plasma miRNA levels with prostate cancer aggressiveness and biochemical recurrence in 480 African American men and 320 European American men This project may show that certain miRNAs are potential targets for treatments with demethylating

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12893 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    that drives the development of rheumatoid arthritis Their studies revealed that inflammatory stimuli trigger cell surface toll like receptors of macrophages the white blood cells that subsequently activate the Unfolded Protein Response transducer IRE1a to promote arthritis syndrome in the tissues around the joints Their work identified a specific IRE1a inhibitor that can efficiently prevent arthritis in animal models The study Toll like receptor mediated IRE1a activation as a therapeutic target for inflammatory arthritis was published in the prestigious scientific journal EMBO Zhang served as a corresponding author The study can be read at http www nature com emboj journal v32 n18 full emboj2013183a html This is a notable work in the understanding of the stress mechanism for the development of rheumatoid arthritis Zhang said For the first time we revealed the molecular targets of Unfolded Protein Response and Toll like Receptor signaling and their interaction mechanism in the progression of inflammatory arthritis Our study not only identified previously unknown molecular targets but also pointed out a specific inhibitor that can efficiently suppress arthritis Dr Zhang said the next step toward the development of therapeutics may be testing the effects of specific inhibitors of Unfolded Protein Response in curing inflammatory arthritis with animal models and clinical trials Rheumatoid arthritis is an autoimmune disease that causes a chronic systemic inflammatory disorder that can affect many tissues and organs but principally flexible joints Rheumatoid arthritis is one of the most common rheumatic diseases affecting approximately 1 3 million people in the United States The disease is three times more common in women than in men and afflicts people of all races The disease can begin at any age but it often occurs in adults between the ages of 40 and 60 The cause is unknown The disease is a costly one for

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12888 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    physics to theorists Peter Higgs and Francois Englert to recognize their work developing the theory of what is now known as the Higgs field which gives elementary particles mass Scientists estimate that visible matter makes up no more than four percent of the total mass of the universe and the long sought Higgs boson particle could be a bridge to understanding the 96 percent that remains obscured A team of Wayne State University researchers led by Paul Karchin Ph D and Robert Harr Ph D professors of physics are members of the CMS experiment who played a significant role in the experimental aspects of the discovery Alexey Petrov Ph D professor of physics and Gil Paz Ph D assistant professor of physics are particle theorists who studied theoretical aspects related to properties of standard and non standard Higgs bosons The Higgs boson at CERN was the culmination of decades of effort by scientists around the world The Wayne State team helped ensure the 24 7 operation of the experiment and analyzing data at the CERN laboratory in Geneva the Fermi National Accelerator Laboratory in Illinois and on Wayne State s campus The four Wayne State researchers are available for comments

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12588 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    proposals not be submitted until the government reopens Both agencies have indicated that they will adjust any proposal deadline dates as necessary Sponsored Program Administration SPA recommends that faculty heed the advice of the agencies and hold off on proposal submission If a faculty member is insistent on submitting SPA will do so but it is at the faculty member s own risk In the meantime proposals may continue to

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12579 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    provide guidance to the research community regarding specific shutdown procedures for the National Science Foundation NSF and the National Institutes of Health NIH NSF Guidance http spa wayne edu docs shutdown 2013 external guidance nsf pdf NIH Guidance http grants nih gov grants guide notice files NOT OD 13 126 html Additionally the Office of Management and Budget has posted agency contingency plans for most agencies at the following link

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12536 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    best training in the latest techniques particularly the integration of medical physics which is now a required aspect in the clinical practice of radiotherapy With the help of a five year 1 57 million grant from the National Cancer Institute of the National Institutes of Health researchers at Wayne State University aim to develop an innovative and advanced education program integrating radiobiology with radiation physics for all oncologists The project Integrated Course in Biology and Physics of Radiation Oncology led by Michael Joiner Ph D professor of radiation oncology in Wayne State s School of Medicine and Monica Tracey Ph D associate professor of instructional technology in Wayne State s College of Education will provide state of the art training in modern high quality image guided radiotherapy ultimately increasing productive research in the field and assuring the future availability of highly qualified teachers The end result will be improved cancer patient care and cure in the United States The program will offer participants a great opportunity to increase their knowledge on the planning and delivery of radiation therapy ultimately improving cancer treatment for patients across the United States said Tracey Researchers and clinicians from any discipline wishing to undertake research in radiation oncology new researchers wishing to enter the field and existing professionals and researchers wishing to refresh and advance their knowledge of state of the art advances will receive significant benefits from this program In addition to a six day workshop lecture and exercise based course the program will train three individuals each year to gain additional knowledge and learn to build their own training programs for their respective institutions This new grant from NCI will enable many exciting and new collaborations across Wayne State s campus between the School of Medicine and the College of Education said Joiner

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12484 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    leadership may not be as important for the success of educational organizations as having a comprehensive understanding of constituents knowledge and expectations of leadership and the leadership roles they play Owens said This study makes a unique contribution to the field by using empirical data to describe concepts and relationships that define participation in educational leadership from the perspective of the led Owens questioned 20 students in a western U S university s Upward Bound program which prepares high school students from low income families and families in which neither parent holds a bachelor s degree to attend college about how they participate in program leadership practices and what that participation implies for themselves and for leaders The results titled The Feeling s Mutual Student Participation in Leadership as a Cooperative Effort were published recently in The Review of Higher Education Participants saw themselves in a take then give interaction Owens said meaning that over time their participation changed from primarily receiving behaviors to a mix of giving and taking leadership practices As they went through the program students said they felt a sense of belonging and that the program could provide help for them he said At that point they made a shift in their sense of confidence and then helped mentor younger students and moved the program along They went from thinking What s in it for me to How can we make this program even stronger and better able to carry out its mission Taking behaviors included signing up receiving support and taking advantage and demonstrated students emerging confidence that the program would be willing and able to deliver what it promised While students reported resisting program staff at times Owens said such resistance constitutes a leadership behavior and can help an organization clarify its goals and

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12452 (2016-02-13)
    Open archived version from archive

  • News and Announcements Archive - Nano@Wayne - Division of Research
    Branch AJOG is the oldest journal in obstetrics and gynecology first published in 1869 The AJOG has published almost 50 percent of the citation classics in the discipline of obstetrics and gynecology in the last 50 years as well as many groundbreaking discoveries that have changed the practice of medicine and the lives of women and their families Examples include The method currently used for the detection of early pregnancy pregnancy test used worldwide The description of the vaginal pap smear by Papanicolaou in 1941 the basis for the Pap test to screen for cervical cancer Polycystic ovarian disease which affects five percent to 10 percent of women of reproductive age The first description of the labor curve which is utilized to assess progress in labor The importance of progesterone in pregnancy maintenance The non stress test used daily in the evaluation of fetal well being The biophysical profile used to assess fetal health The estimation of fetal weight using ultrasound and implemented worldwide to monitor fetal growth Much of the work conducted by the Perinatology Research Branch of NICHD in Detroit has been published on the pages of the AJOG Among the discoveries are methods for prenatal diagnosis of congenital anomalies the evidence that progesterone could reduce the rate of preterm birth and neonatal complications in women with a short cervix by 45 percent and the importance of intra amniotic infection as a cause of preterm labor and delivery Dr Romero is one of the world s foremost authorities in the study of pregnancy and its complications At the Perinatology Research Branch of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Dr Romero leads a research team that has made seminal discoveries related to premature birth and congenital anomalies the two leading causes of infant

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12451 (2016-02-13)
    Open archived version from archive