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  • News and Announcements Archive - Nano@Wayne - Division of Research
    the realistic goal of achieving remyelination Dr Khan said This is a paradigm shift and the start of the next generation of therapies to treat multiple sclerosis that will change its focus to repair rather than inflammation The brain can largely be divided into gray and white areas Neurons are located in the gray area and the white parts are where neurons send their axons similar to electrical cables carrying messages to communicate with other neurons and bring messages from the brain to muscles The white parts of the brain are white because a cell type called oligodendrocytes makes a cholesterol rich membrane called myelin that coats the axons The myelin s function is to insulate the axons similar to the plastic sheath coating electrical cables In addition the myelin speeds communication along axons and makes that communication more reliable In patients with MS their immune system attacks the myelin sheathing The subsequent degradation leads to the messages from the brain to other parts of the body leaking and derailing from their intended target Restoring the myelin sheathing is the goal of Dr Khan s new study The Wayne State University Multiple Sclerosis Center in collaboration with Vaccinex a privately held biotechnology company headquartered in Rochester N Y initiated this early stage dose defining study If successful this will lead to large scale studies with this molecule targeting remyelination in the brain as a primary focus detected by advanced imaging techniques such as magnetization transfer ratio Dr Khan said The real challenge will be to reverse or reduce conduction blocks in the demyelinated nerve that may translate into neurologic improvement If we could achieve that with this approach it opens the door for hundreds of thousands of multiple sclerosis patients for whom no therapy is currently effective This may also

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12440 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    NSF over the next two years to study the current classroom practices associated with STEM courses in four disciplines biology chemistry physics and mathematics The end result will be to improve WSU s graduation rates of STEM undergraduate students support student persistence within STEM majors increase the number of STEM degree recipients and make WSU graduates more effective in the 21st century workplace Nationally students who persist or continue with their STEM programs hovers around 20 to 25 percent with the greatest losses during the first two years of college said Andrew Feig Ph D associate professor of chemistry in WSU s College of Liberal Arts and Sciences and principal investigator of the grant With the help of this grant from NSF we hope to break that pattern and raise the number of students who graduate with degrees in STEM related programs at Wayne State A major focus of the program will be to enhance the classroom and laboratory experiences of Wayne State students through enhancing the teaching skills of faculty The program will create faculty development workshops to facilitate the transition from lecture based to evidence based instructional methods ultimately expanding the use of methods like peer led team learning on campus said Mathew Ouellett associate provost and director of the Office for Teaching and Learning at Wayne State and co principal investigator on the project In addition we will implement improved tracking of our students to understand where the problems in our curricula are that lead to attrition from STEM majors and poor graduation rates The transformational outcomes of this program will not only benefit Wayne State s faculty and students but universities across the United States Wayne State prides itself in being a university of access and one that is highly research intensive said Feig It has

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12415 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    skeletal muscle contractions and heartbeats and enable cells to divide Current clinical trials of several drugs based on Spudich s understanding of exactly how muscles contract offer hope for people prone to heart failure amyotrophic lateral sclerosis and perhaps even the frailties of old age The event will take place in the Marvin I Danto Engineering Development Center EDC Auditorium located at 5050 Anthony Wayne Drive Room 1507 from 1 to 3 30 p m A poster session will kick off the event in the EDC lobby and activity center areas at 1 p m followed by an introduction and presentation of the Zewail Medal at 2 p m in the EDC auditorium and concluding with Dr Spudich s lecture at 2 30 p m The event is free and open to the public but registration is required by calling 313 577 5600 Spudich is the recipient of many prestigious awards including the Guggenheim Fellowship the American Heart Association Basic Research Prize the Alexander von Humboldt Research Award the Biophysical Society Lifetime Research Career Award the Lewis S Rosenstiel Award for Outstanding Research Achievement in the Field of Basic Medical Studies the American Chemical Society s Award for the Investigator

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12350 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    chief of the otolaryngology section in the surgery department at the John D Dingell VA Medical Center said the less than optimal result from UPPP is not surprising In patients with OSAHS obstruction of air flow can occur at multiple levels of the throat UPPP only addresses blockage at the soft palate level In order to be maximally effective the surgeon must evaluate each patient individually to identify the exact site or sites of airway obstruction and then direct the surgical treatments to address those obstructions Lin said Obstruction at the back of the tongue BOT can play a significant role in sleep apnea Traditionally surgical treatment of BOT blockage has been challenging because it s hard for doctors to see and operate in that region Using a robotic device called the da Vinci Surgical System Lin can now gain improved access to the BOT region to safely and precisely remove the excessive tissue causing airway obstruction In this study he reported on the outcome of 12 patients nine women and three men who underwent BOT resection via TORS They were selected for analysis because they underwent removal of excessive BOT tissue and nothing else Two prior studies one from Europe and another from the United States also looked at treatment outcome following TORS assisted BOT surgery in sleep apnea patients However in those studies the BOT surgery was done in conjunction with other upper airway surgeries making it difficult to assess the effectiveness of the BOT procedure alone Because all patients in Lin s study underwent only BOT surgery it is the first to look at the effectiveness of only the TORS assisted BOT resection Despite undergoing only the BOT procedure our patients surgical outcomes appeared similar to those who underwent BOT in addition to other upper airway surgeries

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12271 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    edge interdisciplinary research and mentor junior researchers He will take a temporary leave from Wayne State and begin his new role in Arlington Va starting this fall On behalf of the College of Engineering I congratulate Weisong on this prestigious honor said Wayne State College of Engineering Dean Farshad Fotouhi This is a wonderful opportunity for him to use his academic experience and expertise to help shape a renowned NSF program His time at NSF will also benefit our college and university as the knowledge and experience he gains as a result of program participation at such a high level will be helpful upon his return Added Shi I look forward to gaining experience in the development coordination and management of large and complex Federal programs especially those crosscutting programs such as Science Engineering and Education for Sustainability Smart and Connected Health Big Data and more This experience will in turn help me better understand and identify research problems from a much broader perspective especially the social behavioral and economic impact of our current research At Wayne State Shi directs the Wayne State Mobile and Internet SysTems Laboratory and co directs the university s Laboratory of Sustainable Computing and the Wireless Health Initiative investigating performance trust power and energy efficiency issues of networked computer systems and applications He also serves as the graduate program officer of the computer science department Shi s research has been supported by a variety of governmental and industrial organizations including the NSF Department of Veteran Affairs Air Force Research Laboratory Gates Foundation Swedish Research Council and Michigan Life Science Corridor He has authored a book and published more than 120 publications which have been widely cited more than 2 600 times according to Google Scholar He has chaired several conferences and workshops and served on

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12256 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    provides users the ability to reduce emissions by changing the timing of their electricity use No matter where you are or what time of day this technology will be able to tell you the marginal emissions associated with electricity use for car battery recharging dishwasher use clothes dryer cycling and other common activities Miller said That s important for consumers to know because energy use and damaging emissions are not directly related Without the information regarding real time emissions you might make decisions to reduce energy use at certain times in hopes of reducing polluting emissions while actually shifting your use to a time where the emissions are more detrimental to the environment In previous work with the fund Miller s team developed a fully functional alpha version of LEEM and deployed it in two distinct software products Home Emissions Read Out HERO and Pollutant Emission and Pump Station Optimization PEPSO HERO is a smart phone and web application that turns individual users into active participants in emissions optimization by giving them real time emissions estimations that allow them to selectively time their own electricity use PEPSO is a software program designed to optimize pump operations at water utilities by using an existing U S Environmental Protection Agency hydraulic model in combination with a team designed optimization algorithm that incorporates LEEM Miller s previous project involved designing algorithms that automatically direct pumps to operate at times when the electric power grid is supplied by the cleanest available sources of energy and avoid times when it is supplied by more polluting sources The software was pilot tested using the DWSD water distribution system The current project will explore the potential for embedding LEEM technology into smart appliances and building systems integrating it into the electric vehicle market and working with regulators

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12245 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    cultural exchange program Titled Undergraduate Science Education 2013 the program is funded by an Undergraduate Science Education grant from the Howard Hughes Medical Institute and is designed to expose young scientists to Latin culture through interaction with local undergraduates interested in ecology In return visiting young scientists will host a workshop on urban ecology for UPR M students mainly undergraduates to familiarize them with American culture science and urban environmental issues Doctoral degree student Carly Nowicki of Howell Mich and postdoctoral fellow Abigail Fusaro of Ann Arbor Mich will be the first WSU participants UPR M students are 99 percent Hispanic the largest underrepresented minority URM group in the United States Program officials said better understanding of cultural differences may help institutions retain competent URM students By influencing visiting junior scientists early in their professional careers officials hope to increase awareness and familiarize them with the social and cultural surroundings of Hispanic students hopefully leading to an easier adaptation process for URM students Donna Kashian Wayne State assistant professor of biological sciences serves as adviser to the WSU students who will visit UPR M My ultimate goal is to recruit some great Puerto Rican students here to WSU and provide

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12225 (2016-02-13)
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  • News and Announcements Archive - Nano@Wayne - Division of Research
    researchers at Wayne State University are developing an undergraduate certificate program geared toward training the next generation of nanoengineers The 200 000 Nanotechnology Undergraduate Education NUE grant NUE Development of an undergraduate certificate program in nanoengineering for training the workforce of tomorrow funded by the National Science Foundation will prepare students for flexible employment opportunities and provide them with the necessary experience in cutting edge technologies said Guangzhao Mao Ph D professor of chemical engineering in Wayne State s College of Engineering This new certificate program will help prepare students to gain experience in the field of nanoengineering ultimately training them on emerging technologies said Mao The program will aid in meeting the growing demands of Michigan s manufacturing economy and also other high tech industries that are settling in the state Students in the program will gain hands on knowledge of the field through laboratory and research components enabling them to move from familiar subjects to less familiar research oriented subjects Mao s collaborators in developing the program include Mark Ming Cheng Cheng Ph D assistant professor of electrical and computer engineering Sandro da Rocha Ph D associate professor of chemical engineering Erand Nikolla Ph D assistant professor of chemical engineering and Yong Xu Ph D professor of electrical and computer engineering Nanotechnology has great potential to change our economy and improve our standard of living just as advances in information technology have revolutionized our lives and the economy over the past two decades said Hilary Ratner vice president for research at Wayne State University This grant will provide our students with the opportunity to play an important role in another revolutionary technology by expanding their knowledge and skills beyond their traditional disciplinary training In particular degreed engineers can take advantage of the program for additional training enabling them

    Original URL path: http://research.wayne.edu/nano/news_archive.php?id=12216 (2016-02-13)
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